Protein Alignment GluRIIB and Ir21a

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001097043.1
• Gene: Ir21a / 33157
• FlyBaseID: FBgn0031209
• Length: 842
• Species: Drosophila melanogaster
• Alignment Length: 823
• Identity: 169/823 - (20%)
• Similarity: 284/823 - (34%)
• Gaps: 211/823 - (25%)

  Fly   147 DILASKTFDWKSFTIAYERSSHLIRLQHILAWKQLHKAG--IKMQEFERGDDYRI---LWKRINN 206
            ::|||| |...|:.  :|:::.|:.|.:.:|.:.|:|..  |....|....|..|   |:|.|
  Fly    78 ELLASK-FHVNSYN--FEQTNSLVGLVNKIAQEYLNKCPPVIYYDSFVEKSDGLILENLFKTI-- 137

  Fly   207 AREKFVLLDCPSDILVDVINASIGYNMTGSFNHLFLTNLDTHLSGIDGFYSRDFTVAVAAVRIRT 271
                      |.......|||.  |.   :.|..|.:::|.:......|.|       ..:..|.
  Fly   138 ----------PITFYHGEINAD--YE---AKNKRFTSHIDCNCKSYILFLS-------DPLMTRK 180

  Fly   272 YVPPPVHDEIDVFDNSVDTRFSSLGSQLVYDSIVLFYNALLEISQRPGFYIPNFSCGRGFWQPGP 336
            .:.|.....:.:...|...|.....|..:..:||    .||.|.:
  Fly   181 ILGPQTESRVVLVSRSTQWRLRDFLSSELSSNIV----NLLVIGE-------------------- 221

  Fly   337 RLVEQMKQITPKMVKPPFKTQRLQINADGQREDFNLEVYNPIIDRVTHIWNKEFQLVDFEKLREN 401
                  ..:...|.:.|:.....::.|||      |....|:   |...|.|
  Fly   222 ------SLMADPMRERPYVLYTHKLYADG------LGSNTPV---VLTSWIK------------- 258

  Fly   402 STQALKQKRLQ---NKEDFSQKPIRYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYML 463
              .||.:..:.   :|..|.....|:.::. ..:|.|.:|.........|..|::|....|:.|:
  Fly   259 --GALSRPHINLFPSKFQFGFAGHRFQISA-ANQPPFIFRIRTLDSSGMGQLRWDGVEFRLLTMI 320

  Fly   464 AQECKF--DFNFEPVRDNKYGSYDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPF 526
            ::...|  |....|.|.|..|..|.       |..|:|:....||:..:.|||.|  ::|..
  Fly   321 SKRLNFSIDITETPTRSNTRGVVDT-------IQEQIIERTVDIGMSGIYITQER--LMDSA--- 373

  Fly   527 MQLG--------ISILSYKEPPPKADIYAFLNPYNAEVWLFVMIAMMITAFALIFTGRID----Q 579
            |.:|        |::.|...|..:    |.:.|:...||:.::...:...|.::||.|:.    .
  Fly   374 MSVGHSPDCAAFITLASKALPKYR----AIMGPFQWPVWVALICVYLGGIFPIVFTDRLTLSHLM 434

  Fly   580 YEWDQPVENVNREMERQNIWHLSNALWLVLGSMLN------QGCDLLPRGLPMRLLTAFWWIFAL 638
            ..|.: |||:               .|.|.|...|      :......|....|||...:|:|.:
  Fly   435 GNWGE-VENM---------------FWYVFGMFTNAFSFTGKYSWSNTRKNSTRLLIGAYWLFTI 483

  Fly   639 LISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKML 703
            :|:..|...:.||:|.......:.|:.||:.. ..:.||:..|....:|..|........:.||
  Fly   484 IITSCYTGSIIAFVTLPAFPDTVDSVLDLLGL-FFRVGTLNNGGWETWFQNSTHIPTSRLYKKM- 546

  Fly   704 SFKPDAFTKNNEEGVDRVKLS-KGTYAFLMETTNLQYYVQRNCELTQIG---------ESFGEKH 758
                 .|..:.:||:..|..| ...||||.....|:|.||.|.....|.         |.|....
  Fly   547 -----EFVGSVDEGIGNVTQSFFWNYAFLGSKAQLEYLVQSNFSDENISRRSALHLSEECFALFQ 606

  Fly   759 YGIAVPLNADFRSNLSVGILRLSERGELFKLRNK--WFNSNES-------TCDSNVPTI--DDGQ 812
            .|...|..:.::..:...||...:.|.:.|:.|:  |.....|       :..:::..|  ::.|
  Fly   607 IGFLFPRESVYKIKIDSMILLAQQSGLIAKINNEVSWVMQRSSSGRLLQASSSNSLREIIQEERQ 671

  Fly   813 FDMDSVGGLFVVLIVGVVVGLVIGVAEFLWHVQRISVKEKIPPMLALKAEFYFVIRFWLTRKPLH 877
            .......|:|:::.:|..:|....|:|.:..:                           |.|...
  Fly   672 LTTADTEGMFLLMALGYFLGATALVSEIVGGI---------------------------TNKCRQ 709

  Fly   878 TYRQSRDSTSTGYSS----------LEQITSASSAKKKKKTRR 910
            ..::||.|.::.:||          .||:    |..|:|..||
  Fly   710 IIKRSRKSAASSWSSASSGSMLRTNAEQL----SHDKRKANRR 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	49/250 (20%)
		ANF_receptor	41..378	CDD:279440	45/235 (19%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	93/404 (23%)
		Lig_chan	555..822	CDD:278489	64/297 (22%)
Ir21a	NP_001097043.1	Periplasmic_Binding_Protein_Type_2	289..583	CDD:304360	80/332 (24%)
		Lig_chan	407..662	CDD:278489	61/277 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910