DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GluRIIB and Ir7g

DIOPT Version :9

Sequence 1:	NP_523485.3	Gene:	GluRIIB / 33789	FlyBaseID:	FBgn0020429	Length:	913	Species:	Drosophila melanogaster
Sequence 2:	NP_001368933.1	Gene:	Ir7g / 31694	FlyBaseID:	FBgn0029968	Length:	607	Species:	Drosophila melanogaster

Alignment Length:	445	Identity:	95/445 - (21%)
Similarity:	153/445 - (34%)	Gaps:	123/445 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   447 EGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGSYDANTDEWDGIIRQLIDNNAQIGICDLT 511
            ||.....|....|:..|::...|...|..::|..     .|...|..  :||:....|..|..|.
  Fly   229 EGQRELRGLEGRLLQELSRRMNFSIQFSGLQDQL-----KNRTTWTE--KQLLQKLVQERIAHLA 286

  Fly   512 ITQARRSV---VDFTVPFMQ-----LGISILSYKEPPPKADIYAFLNPYNAEVWLFVMIAMM-IT 567
            |...|:.:   .:.|..|..     :|..:|: .......:|::|  |:.|..|:.::.:.: |:
  Fly   287 IGYVRKRIQYATNLTPVFPHYSNRVVGCLLLN-AHNLTSLEIWSF--PFQALTWICLVFSFLSIS 348

  Fly   568 AFALIFTGRIDQYEWDQPVENVNREMERQNIWHLSNA---LWLVLG-SMLNQGCDLLPRGLP-MR 627
            ..||:                           |...|   |.|||. ...:.|..:.|...| ::
  Fly   349 CLALL---------------------------HXRGAGDRLALVLAVYAASLGLPIDPPERPSLQ 386

  Fly   628 LLTAFWWIFALLISQTYIAKLAAFITSSKIAGDI-GSLHDLVDQNKVQFGTIRGGATSVYFSESN 691
            ||.|.|.||.|::...|.| |..||....:...: |:|.||...:   :..:.|..|      ..
  Fly   387 LLFASWLIFGLIVRSMYSA-LLFFILRYHLHQRLPGNLQDLTHGD---YAAVMGRTT------LQ 441

  Fly   692 DTDNRMAWNKMLSFKPDAFTKNNEEGV----DRVKLSKGT------YAFLMETTNLQYYVQRNCE 746
            |.....:...:|..|....|...||.|    ||..|.:|.      :..:.:...|        .
  Fly   442 DLREVPSLQDLLGLKSVIVTSEREEEVLRTLDRCTLREGAGSHPLFFGLISQDALL--------H 498

  Fly   747 LTQIGESFG------------------EKHYGIAVPLNADFRSNLSVGILR------LSERGELF 787
            |||.|...|                  :||..:|..|:....|..|||::.      .|||
  Fly   499 LTQRGHRAGAYHIIPQDVLEQQLAIYLQKHSHLASHLDHLVMSIRSVGLVHHWAGQMASER---- 559

  Fly   788 KLRNKWFNSNESTCDSNVPTIDDGQFDMDSVGGLFVVLIVGV-VVGLVIGVAEFL 841
                 :|.|.....:..:     .|.|:.:|    .:|..|: ::.||:.:.|.|
  Fly   560 -----YFRSRFLYREKRI-----RQPDLWAV----YILTAGLYLLSLVVFICELL 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377
		ANF_receptor	41..378	CDD:279440
		PBP2_iGluR_Kainate	422..795	CDD:270432	84/396 (21%)
		Lig_chan	555..822	CDD:278489	64/307 (21%)
Ir7g	NP_001368933.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462638
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840