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Protein Alignment GluRIIB and Grik1

DIOPT Version :9

Sequence 1:	NP_523485.3	Gene:	GluRIIB / 33789	FlyBaseID:	FBgn0020429	Length:	913	Species:	Drosophila melanogaster
Sequence 2:	NP_001104587.1	Gene:	Grik1 / 29559	RGDID:	2732	Length:	949	Species:	Rattus norvegicus

Alignment Length:	951	Identity:	269/951 - (28%)
Similarity:	466/951 - (49%)	Gaps:	127/951 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 VIKIGAIFFDTEMKLAD----AFSAALEEVN-----AINPALKLDAIKRYVTVDDSIVLQDISCD 79
            |::||.||...|.:..:    ||..|:..:|     ..|..|..| |:| :.:.||......:||
  Rat    36 VLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYD-IQR-INLFDSFEASRRACD 98

  Fly    80 LIGSGVAAIFGPSSKTNSDIVEVLCNMTGIPHLQFDW-HPQQSNRERMNHQLTVNVAPMELFLSA 143
            .:..||||:||||..::...|:.:||...:||:|..| ||...:|:    ...:|:.|....:|.
  Rat    99 QLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDSRD----LFYINLYPDYAAISR 159

  Fly   144 AFSDILASKTFDWKSFTIAYERSSHLIRLQHILAWKQLHKAGIKMQEFERGD-DYRILWKRINNA 207
            |..|::.  .::||:.|:.||.|:.|||||.::.....:...||:::....: |.:.|.|.:..:
  Rat   160 AVLDLVL--YYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPPANKDAKPLLKEMKKS 222

  Fly   208 REKFVLLDCPSDILVDVINASIGYNMTGSFNHLFLTNLDTHLSGIDGFYSRDFTVAVAAVRI--- 269
            :|.:|:.||..:...:::...:...|...:.|.|.|.||  |..:|....|...|.:...|:
  Rat   223 KEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLD--LFALDLELYRYSGVNMTGFRLLNI 285

  Fly   270 ---------------RTYVPPPVHDEIDVFDNSVDTRFSSLGSQLVYDSIVLFYNALLEISQRPG 319
                           |...||  ..|..:.|..:.|.     :.|:||::.:...|....||
  Rat   286 DNPHVSSIIEKWSMERLQAPP--RPETGLLDGMMTTE-----AALMYDAVYMVAIASHRASQ--- 340

  Fly   320 FYIPNFSCGRGF-WQPGPRLVEQMKQITPKMVKPPFKTQRLQIN-ADGQREDFNLEVYN------ 376
            ..:.:..|.|.. |:.|||.:..:|:     .:....|.|:..| .||.|:||:|::.:
  Rat   341 LTVSSLQCHRHKPWRLGPRFMNLIKE-----ARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGT 400

  Fly   377 -----PIIDRVTHIW--------NKEFQLVDFEKLRENS-TQALKQKRLQNKEDFSQKPIRYTVA 427
                 .:...:..:|        |....:.|..:.|.|: |.:|..:.|             .|.
  Rat   401 EKASGEVSKHLYKVWKKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTL-------------IVT 452

  Fly   428 TRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGSYDANTDEWD 492
            |.:.:||..:|:..:.::  ||:|||||.:||:..|:....|.::.:.|.|.|||:.: :..||:
  Rat   453 TILEEPYVMYRKSDKPLY--GNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQN-DKGEWN 514

  Fly   493 GIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPKADIYAFLNPYNAEVW 557
            |::::|||:.|.:.:..||||..|..|:||:.|||.||||||..|.......:::||||.:.::|
  Rat   515 GMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIW 579

  Fly   558 LFVMIAMMITAFALIFTGRIDQYEWDQPVE-NVNREMERQNIWHLSNALWLVLGSMLNQGCDLLP 621
            ::|::|.:..:..|....|...|||..|.. |.:.::...| :.|.|:.|..:|:::.||.:|:|
  Rat   580 MYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENN-FTLLNSFWFGVGALMQQGSELMP 643

  Fly   622 RGLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNKVQFGTIRGGATSVY 686
            :.|..|::...||.|.|:|..:|.|.||||:|..::...|.|..||..|.|:::|.:|.|:|..:
  Rat   644 KALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTF 708

  Fly   687 FSESNDTDNRMAWNKMLSFKPDAFTKNNEEGVDRVKLSKGTYAFLMETTNLQYYVQRNCELTQIG 751
            |.:|..:.....|..|.|.:..|..||::||:.||..:  .||.|||:|:::|..||||.|||||
  Rat   709 FKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTT--DYALLMESTSIEYVTQRNCNLTQIG 771

  Fly   752 ESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSNESTCDSNVPTIDDGQ---F 813
            .....|.||:..|:.:.:|..:::.||:|.|.|:|..::.||:..|      ..|..|..:   .
  Rat   772 GLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGN------GCPEEDSKEASAL 830

  Fly   814 DMDSVGGLFVVLIVGVVVGLVIGVAEFLWHVQR---ISVKEKIPPMLALKAEFYFVIRFWLTRKP 875
            .::::||:|:||..|:|:.:.:.:.|||:..::   :..|.|     :.:..|||       |..
  Rat   831 GVENIGGIFIVLAAGLVLSVFVAIGEFLYKSRKNNDVEQKGK-----SSRLRFYF-------RNK 883

  Fly   876 LHTYRQSRDSTST----GYSSLEQ---ITSASSAKKKKKTR 909
            :..:...::|...    .::::.:   |:..:..|.|||:|
  Rat   884 VRFHGSKKESLGVEKCLSFNAIMEELGISLKNQKKLKKKSR 924

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.