DRSC/TRiP Functional Genomics Resources

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Protein Alignment GluRIIB and C08B6.5

DIOPT Version :9

Sequence 1:NP_523485.3 Gene:GluRIIB / 33789 FlyBaseID:FBgn0020429 Length:913 Species:Drosophila melanogaster
Sequence 2:NP_505601.1 Gene:C08B6.5 / 182390 WormBaseID:WBGene00007426 Length:423 Species:Caenorhabditis elegans


Alignment Length:442 Identity:88/442 - (19%)
Similarity:163/442 - (36%) Gaps:92/442 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   454 GYAVDLIYMLAQECKFDF-------NFEPVRDNKYGSYDANTDEWDGIIRQLIDNNAQIGICDLT 511
            |..:::|.|:.|...:.:       .|..|.|......|.|   :.||:..|..:...:....:.
 Worm    10 GAEIEIISMVMQILDWQWEVIDTEKEFNVVNDFGNPQPDGN---FSGIMGLLAQDKIDMSGLSMR 71

  Fly   512 ITQARRSVVDFTVP---FMQLGISILSYKEPPPKADIYAFL-NPYNAEVWLFVMIAMMITAFALI 572
            ||.||.....||.|   |.|:.|.     :.|.:.|...|: .|:..::|| :::|.::.|..:.
 Worm    72 ITPARMEFAHFTFPIRYFQQVYII-----KRPAENDFRNFVFAPFTTDMWL-LLLATIMGASTMR 130

  Fly   573 FTGRIDQYEWDQPVENVNREMERQNIWHLSNALWLVLGSMLNQGCDLLPRGLPMRLLTAFWWIFA 637
            |...:   .||      :|...:.||:  ::::....|.||.|... .|..:...||..|..:..
 Worm   131 FACAL---YWD------SRVGSKFNIY--TSSVLETFGLMLKQRVQ-DPTAVSTMLLEGFLIVAM 183

  Fly   638 LLISQTYIAKLAAFIT---SSKIAGDIGSLHDLVDQNK-VQFGTIRGGATSVYFS---ESNDTDN 695
            :.|:|.|...:.:.:|   ||:|.    .||    ||: ::....:....:.||:   |.:...|
 Worm   184 MSIAQYYQTSMNSRLTAPPSSRIP----FLH----QNQLIELLLDKETYLTYYFNLTLEGSTEKN 240

  Fly   696 RMAWNKMLSFKPDAFTKNNEEGVDRVK-LSKGTYAFLMETTNLQYYVQRNCELTQIGESFGEKHY 759
            .....:.|:..|.......   .|.:| :.||..          :|...:.|......|..:|..
 Worm   241 EYNIKRALAMNPIVVRARE---ADLIKEIQKGGV----------FYSTYDIEFLPQAVSVWDKRQ 292

  Fly   760 GIAVPLNADFRSNLSVGIL-------RLSERGELFKLRNK----------------WFNSNESTC 801
            |:.|..:..       |||       .:|.| :|.::.||                .:.:.:...
 Worm   293 GLTVIRDTS-------GILSYVAFGFSISNR-KLCQMFNKALLKILPGIASITLGPGYGTKKQPE 349

  Fly   802 DSNVPTIDDGQFDMDSVGGLFVVLIVGVVVGLVIGVAEFLWHVQRISVKEKI 853
            |..|............:..||.:.::|..:.|...:.|.::...|:..::|:
 Worm   350 DITVQVKKTRLSLKKHLEQLFYIYLIGCGIALAFFIIEKVFFRMRVLKRQKV 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GluRIIBNP_523485.3 PBP1_iGluR_Kainate 26..393 CDD:107377
ANF_receptor 41..378 CDD:279440
PBP2_iGluR_Kainate 422..795 CDD:270432 79/382 (21%)
Lig_chan 555..822 CDD:278489 55/297 (19%)
C08B6.5NP_505601.1 Periplasmic_Binding_Protein_Type_2 13..>116 CDD:304360 25/110 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1052
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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