Protein Alignment GluRIIB and glr-8

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 116/530 - (21%)
• Similarity: 196/530 - (36%)
• Gaps: 111/530 - (20%)

  Fly   400 ENSTQALKQKRLQNK--EDFSQK---PIRYTVATRVGKPY-------FSWRE------------- 439
            ||:|......|..|.  |..::|   |.:.::.:..|..|       ||..|
 Worm     7 ENTTADPNSIRTLNNILESINEKVAHPPQTSLTSDYGDAYTLSNEKHFSLSEMKGRTLKMVVPAI 71

  Fly   440 EPEGVHY----EGNERFEGYAVDLIYMLAQEC--KFDFNFE--PVRDNKYGSYDANTDEWDGIIR 496
            ||..|:|    :.....:||...::..:.:|.  :.:..:|  |...:.:|.|  ....|.|...
 Worm    72 EPPYVNYVNFSDAAVTDKGYGPGVVMEILKEIGKRLNLTYEILPALGSTWGEY--LNGSWTGAFG 134

  Fly   497 QLIDNNAQIGICDLTITQARRSVV-DFTVPFM--QLGISILSYKEPPPKAD---IYAFLNPYNAE 555
            ||:.....: :....|.:..|||: |.|.||.  ..||.|.|    |.|.:   :.....|::.|
 Worm   135 QLVRGEVDL-LAGGAIMEYDRSVIADLTYPFQFEPTGIMIRS----PEKYEDDTLLIVTEPFSWE 194

  Fly   556 VWLFVMIAMMITAFALIFTGRIDQYEWDQPVENVNREMERQNIWHLSNALWLVLGSMLNQGCDLL 620
            ||       :|||..::.:|.|...     :.|:.|::..:.......::|:.....:.||....
 Worm   195 VW-------VITAAVILISGVIFLV-----MTNIIRKVYEEMTVTPFESIWVFFSIFVQQGLPEQ 247

  Fly   621 PRGLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNKVQFGTI------- 678
            ||....|:|.|.||:.::.:|.|:...|.|...              ||:..|.|..|
 Worm   248 PRSWSCRVLVALWWLASITLSATFTGSLVALFA--------------VDKTNVPFQNIDQLVRLV 298

  Fly   679 RGGATSVYFSESNDTDNRM-----------AWNKMLSFKPDAFTKNNEEGVDRVKLSKGTYAFLM 732
            :.|...:...|::.|...|           .|::|:......:......||..|:.:.| ||.|.
 Worm   299 KQGKFEIVMDENSFTRTEMIARSKLPVYRDLWHEMIVNHKVKYVNGIARGVAFVRANPG-YALLG 362

  Fly   733 ETTNLQYYVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSN 797
            ....|.:|...:|::....:.....:..|.:..|:.:....|..|..:.|||    ...||....
 Worm   363 PMATLNFYAYSDCKVILFNDGILPVYLSIPLVKNSIYSPYFSTKIREMVERG----FTQKWIADY 423

  Fly   798 ES--------TCDSNVPTIDDGQF-DMDSVGGLFVVLIVGVVVGLVIGVAEFLWHVQRISVKE-- 851
            .|        .|:|.  ||....: |:....|.|.|.:.|..:||.:.|.||::...|..:.:
 Worm   424 RSYVAMQKINECNST--TIGPKSYLDLKRAQGAFWVFLGGAGLGLALFVGEFIFKFFREKMTKHT 486

  Fly   852 ---KIPPMLA 858
               .:||.:|
 Worm   487 KTTTVPPEVA 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377
		ANF_receptor	41..378	CDD:279440
		PBP2_iGluR_Kainate	422..795	CDD:270432	89/424 (21%)
		Lig_chan	555..822	CDD:278489	61/293 (21%)
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	84/399 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770