Protein Alignment GluRIIB and grik3

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: XP_031752773.1
• Gene: grik3 / 100498426
• XenbaseID: XB-GENE-6050069
• Length: 919
• Species: Xenopus tropicalis
• Alignment Length: 907
• Identity: 268/907 - (29%)
• Similarity: 449/907 - (49%)
• Gaps: 87/907 - (9%)

  Fly    24 VIKIGAIFFDTE---------MKLADAFSAALEEVNAI---NPALKLDAIKRYVTVDDSIVLQDI 76
            ||:||.||...|         .:.|..|||::...|..   |..|..| |:| :.:.||......
 Frog    35 VIRIGGIFEHLEGPTGQLVSAEEQAFRFSASIINRNRTLLPNTTLTYD-IQR-INLYDSFEANRK 97

  Fly    77 SCDLIGSGVAAIFGPSSKTNSDIVEVLCNMTGIPHLQFDW-HPQQSNRERMNHQLTVNVAPMELF 140
            :||.:..||.||||||..::|:.|:.:||...:||:|..| |....||:    ...||:.|....
 Frog    98 ACDQLALGVVAIFGPSHSSSSNAVQSICNALEVPHIQVRWKHHPLDNRD----SFYVNLYPDYAS 158

  Fly   141 LSAAFSDILASKTFDWKSFTIAYERSSHLIRLQHILAWKQLHKAGIKMQEF-ERGDDYRILWKRI 204
            ||.|..|::  :...|:|.|:.|:.|:.|||||.::.....:...:|:::. ...:|.|.|.|.:
 Frog   159 LSHAILDLV--QFLKWRSATVVYDDSTGLIRLQELIMAPARYNIRLKIRQLPPESEDARPLLKEM 221

  Fly   205 NNAREKFVLLDCPSDILVDVINASIGYNMTGSFNHLFLTNLDTHLSGIDGF-YSRDFTVAVAAVR 268
            ...||..::.||...:...::..::...|...:.|...|.||.:...::.: ||   .|.:...|
 Frog   222 KRGREFRIIFDCSHTMAAQILRQAMAMGMMTEYYHYIFTTLDLYALDLEPYRYS---GVNLTGFR 283

  Fly   269 IRTYVPPPVHDEIDVFD----NSVDTRFSSLGSQLVYDSIVLFYNALLEIS---QR-PGFYIPNF 325
            |.....|.|...:|.:.    .:.....|.|...::.....|.|:|:..:|   || |...:.:.
 Frog   284 ILNVDNPYVSSIVDKWSMERHQATPKPESGLLDGIMTTDAALTYDAVHIVSVCYQRAPQMTVNSL 348

  Fly   326 SCGR-GFWQPGPRLVEQMKQITPKMVKPPFKTQRLQIN-ADGQREDFNLEVYNPIIDRVTHI--W 386
            .|.| ..|:.|.|.:..:|:...:.:     |.|:..| ..|.|.||:|::.:...|.:..:  |
 Frog   349 QCHRHKAWRFGSRFMNFIKEAQWEGL-----TGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGTW 408

  Fly   387 NKEFQLVDFEKLRENSTQALKQKRLQNKEDFSQKPIRYTVATRVGKPYFSWREEPEGVHYEGNER 451
            |....|        |.|:..:.:.....|..:.:.:  .|.|.:.:||..::.....:.  |.:|
 Frog   409 NPSDGL--------NITETARGRGPNISESLTNRTL--IVTTVLEEPYVMFKRSDTPLF--GKDR 461

  Fly   452 FEGYAVDLIYMLAQECKFDFNFEPVRDNKYGSYDANTDEWDGIIRQLIDNNAQIGICDLTITQAR 516
            |||:.:||:..:|:...||::...|.|.||||.| ...:|:|::::|||:.|.:.:..||||..|
 Frog   462 FEGFCIDLLKKIAEILGFDYDIRLVEDAKYGSQD-EKGQWNGLVKELIDHKADLAVAPLTITHVR 525

  Fly   517 RSVVDFTVPFMQLGISILSYKEPPPKADIYAFLNPYNAEVWLFVMIAMMITAFALIFTGRIDQYE 581
            ..|:||:.|||.||||||..|.......:::||||.:.::|:::::|.:..:..|....|...||
 Frog   526 EKVIDFSKPFMTLGISILYRKANGTAPSVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYE 590

  Fly   582 W-DQPVENVNREMERQNIWHLSNALWLVLGSMLNQGCDLLPRGLPMRLLTAFWWIFALLISQTYI 645
            | |....|...::...| :.|.|:.|..:|:::.||.:|:|:.|..|::...||.|.|:|..:|.
 Frog   591 WYDAHPCNPGTDVVENN-FTLLNSFWFAVGALMQQGSELMPKALSTRIIGGIWWFFTLIIISSYT 654

  Fly   646 AKLAAFITSSKIAGDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAF 710
            |.||||:|..::...|.|..||..|.|:::|.:..|||..:|.:|:.:.....| ..:|.:|.|.
 Frog   655 ANLAAFLTVERMESAIDSADDLAKQTKIEYGAVVDGATMNFFKKSHISTFEKMW-AFMSSRPSAL 718

  Fly   711 TKNNEEGVDRVKLSKGTYAFLMETTNLQYYVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSV 775
            .|:||||:.|| || ..||.|||:|.::|..||||.|||||.....|.|||..|:.:.:|..:|:
 Frog   719 VKSNEEGIQRV-LS-ADYALLMESTAIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDRISI 781

  Fly   776 GILRLSERGELFKLRNKWFNSNESTCDSNVPTIDDGQFDMDSVGGLFVVLIVGVVVGLVIGVAEF 840
            .||:|.|..|:.|::.:|:.|.....:.|.   :.....:.::||:|:||..|:::.:|:.:|||
 Frog   782 AILQLQEADEIHKMKERWWRSGGCPEEKNK---EASALGIQNMGGIFIVLAGGLILSVVVAMAEF 843

  Fly   841 LWHVQRISVKEKIPPMLALKAEFYFVIRFWLT------RKP-------------LHTYRQSR 883
            ::.:::.:.:|:......:..|    ||..||      .||             :||:...|
 Frog   844 VYKLRKTAEREQRSFCSTMADE----IRLSLTCQRRVKHKPQPPVMVKSDAVINMHTFNDRR 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	103/393 (26%)
		ANF_receptor	41..378	CDD:279440	94/352 (27%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	136/373 (36%)
		Lig_chan	555..822	CDD:278489	91/267 (34%)
grik3	XP_031752773.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D60688at33208
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920