Protein Alignment GluRIIB and grik5

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: XP_002936446.1
• Gene: grik5 / 100497490
• XenbaseID: XB-GENE-953974
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 950
• Identity: 250/950 - (26%)
• Similarity: 439/950 - (46%)
• Gaps: 115/950 - (12%)

  Fly     7 LVLLALAIASGANEDTLVIKIGAIFFDTEM-----KLADAFSAALEEVNAINPA----------L 56
            |:||.|:..|........:::.||..|..:     :|  |.:.|.|.:|:....          .
 Frog    10 LLLLLLSFTSPGVSLLSSLRVAAILDDQTVCGRGERL--ALALAREHINSHTQGSASGRVEVEIF 72

  Fly    57 KLDAIKRYVTVDDSIVLQDISCDLIGSGVAAIFGPS-SKTNSDIVEVLCNMTGIPHLQFDWHPQQ 120
            :|....:|.|.       |..|.::..||.::.||| |..::..|..:|....|||::..  |::
 Frog    73 ELQKDSQYETT-------DTMCQILPKGVVSVLGPSTSPASASTVSHICGEKEIPHIKVG--PEE 128

  Fly   121 SNRERMNHQLTVNVAPMELFLSAAFSDILASKTFDWKSFTIAYERSSHLIRLQHILAWKQLHKAG 185
            :.:.:.....:|::.|....:|.|.|.||  |:|...|.::...::..|:||:.::....:.|..
 Frog   129 APKLQYLRFASVSLYPSNEDISLAVSHIL--KSFHNPSTSLICAKAECLLRLEELVRQFLISKDT 191

  Fly   186 IKMQEFERGDDYRILWKRINNAREKFVLLDCPSDILVDVINASIGYNMTGSFNHLFLTNLDTHLS 250
            :.::..:..:|...|.|.|.:.:...:::|..:.:...::..:....||.:.....||.:|..|.
 Frog   192 LSVRMLDESNDPTPLLKEIRDDKVSTIIIDANATVSHLILKKASELGMTSAHYKYILTTMDFPLL 256

  Fly   251 GIDGFYSRDFTVAVAAV-----------------------RIRTYVPPPVHDEIDVFDNSVDTRF 292
            .::|..|....:...::                       .:.||:.|
 Frog   257 SLEGIVSDQSNILGFSMYNSSHPFYLEFLRSLNMSWRENCELSTYLGP----------------- 304

  Fly   293 SSLGSQLVYDSIVLFYNALLEISQRPGFYIPNFSCGRG-FWQPGPRLVEQMKQITPKMVKPPFKT 356
             :|.:.|::|::.:..:|:.|:::.....:...||... .||.|..|:..:     :||:....|
 Frog   305 -ALSAALMFDAVHVVVSAVRELNRSQEIGVKQLSCSTSQIWQHGTSLMNYL-----RMVEYDGLT 363

  Fly   357 QRLQINADGQREDFNLEVYNPIID--RVTHIWNKEFQLVDFEKLRENSTQALKQKRLQNKEDFSQ 419
            .|::.|:.|||.::.|.:.....|  |...:|.....|.    :...|......:.|:||
 Frog   364 GRVEFNSKGQRTNYTLRILEKAGDGHREIGVWYSNRTLA----MNATSLDLSTSETLENK----- 419

  Fly   420 KPIRYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGSY 484
               ...|.|.:..||...:.....:  .||:::||:..:::..||...:|::..:.|.|..||:.
 Frog   420 ---TLVVTTILENPYMMRKSNYRSL--SGNDQYEGFCAEMLMELAALLRFNYKIKLVEDGLYGAP 479

  Fly   485 DANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPKADIYAFL 549
            :.| ..|.|::.:||:..|.:.:...|||..|..|:||:.|||.||||||...:...|...::||
 Frog   480 EPN-GSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVQMGRKPGYFSFL 543

  Fly   550 NPYNAEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVENVNREMER--QNIWHLSNALWLVLGSM 612
            :|::..||||:::|.:..:..|....|:..|||..| ....||...  :|.:.|.|:||..:|..
 Frog   544 DPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNP-HPCLRERHHILENQYTLGNSLWFPVGGF 607

  Fly   613 LNQGCDLLPRGLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNKVQFGT 677
            :.||.:::||.|..|.::..||.|.|:|..:|.|.||||:|..::...|.|..||.||..:::||
 Frog   608 MQQGSEVMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESADDLADQTNIEYGT 672

  Fly   678 IRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGVDRVKLSKGTYAFLMETTNLQYYVQ 742
            |.||:|..:|..|.....:..||.|.|.:|..|.|:.|||:.||..|:  ||||:|:|..:|:.:
 Frog   673 IHGGSTMTFFQNSRYQTYQRMWNYMNSKQPSVFVKSTEEGIARVLNSR--YAFLLESTMNEYHRR 735

  Fly   743 RNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSNESTCDSNVPT 807
            .||.|||||.....|.|||.:||.:.:|..:::.||:|.|...|..|:.||:...:  |    |.
 Frog   736 LNCNLTQIGGLLDTKGYGIGMPLGSPYRDEITLAILQLQENNRLEILKRKWWEGGK--C----PK 794

  Fly   808 IDDGQ---FDMDSVGGLFVVLIVGVVVGLVIGVAEFLWHVQRISVKEKIPPMLALKAEFYFVIRF 869
            .:|.:   ..|:::||:|||||.|:::.:.:.:.||:|..:|....|:|.....:.:|....:..
 Frog   795 EEDHRAKGLGMENIGGIFVVLICGLIIAVFVAIMEFVWSTRRSVDNEEISVCQEMLSELRSAVSC 859

  Fly   870 WLTRKPLHTYRQSRDSTSTGYSSLEQITSASSAKKKKKTR 909
            ..|.:..|..|..|        .|...|..|.::..:.||
 Frog   860 KKTSRSRHRRRPPR--------HLHGRTLLSLSRPPRSTR 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	78/408 (19%)
		ANF_receptor	41..378	CDD:279440	71/371 (19%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	134/374 (36%)
		Lig_chan	555..822	CDD:278489	99/271 (37%)
grik5	XP_002936446.1	PBP1_iGluR_Kainate_KA1_2	27..405	CDD:380616	79/417 (19%)
		Periplasmic_Binding_Protein_Type_2	418..788	CDD:389745	136/383 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D60688at33208
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920