Protein Alignment GluRIIB and grid1

DIOPT Version :9

• Sequence 1: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Sequence 2: NP_001096470.1
• Gene: grid1 / 100125089
• XenbaseID: XB-GENE-990290
• Length: 1009
• Species: Xenopus tropicalis
• Alignment Length: 992
• Identity: 221/992 - (22%)
• Similarity: 409/992 - (41%)
• Gaps: 178/992 - (17%)

  Fly    24 VIKIGAIFFDTEMKLADAFSAALEEVNAINPALKLDAIK---RYVTVDDSIVLQDISCDLIGSGV 85
            :|.|||||.:..:|..:.|..|:.:::..:..|:.:.|.   :::..::.......:|||:..|:
 Frog    23 IIHIGAIFEENAVKDDEVFQLAVSDLSLNDDILQSEKITYSIKFIEANNPFQAVQEACDLMTQGI 87

  Fly    86 AAIFGPSSKTNSDIVEVLCNMTGIPHL--------------QFDWHPQQSNRERMNHQLTVNVAP 136
            .|:...:...:::.::.|.:...|||:              ||:..|:       ..:.|:...|
 Frog    88 LALVTSTGCASANALQSLTDAMHIPHIFVQRNSGGSPRTVCQFNPSPE-------GEEYTLAARP 145

  Fly   137 MELFLSAAFSDILASKTFD--WKSFTIAYERSSHLIRLQHILAWKQLHKAG--IKMQEFERGDD- 196
                 ....:|::.....:  |:.|.:.|:....:..||..|  .|..:.|  :.:|:.:|...
 Frog   146 -----PVRLNDVMLKLVTELRWQKFIVFYDSDYDIRGLQGFL--DQASRLGLDVSLQKVDRNISR 203

  Fly   197 -YRILW-----KRINNARE---KFVLLDCPSDILVDVINASIGYNMTGSFNHLFLTNLDTHLSGI 252
             :..|:     :.:|..|:   :.:||..|.. ....|:.::..|:....:|....|.:.:.:.|
 Frog   204 VFATLFTSMKTEELNRYRDTLRRAILLLSPRG-AQSFISEAVETNLASKDSHWVYVNEEINDAEI 267

  Fly   253 -DGFYSRDFTVAVAAVRIRTYVPPPVHDEIDVFDNSV-----DTRFSSL--------------GS 297
             :..:|....:.|    ||...|       .:.||::     :.|.:||              .:
 Frog   268 VELVHSALGRITV----IRQIFP-------SLKDNNIRCVRNNHRIASLPCDPQEGYLQMLQVSN 321

  Fly   298 QLVYDSIVLFYNAL-LEISQRPGFYIPNFSCGRGF---WQPGPRLVEQMK--QITPKMVKPPFKT 356
            ..:|||:::..||. .::..|....:.:.:|.|..   |..|..:::.:|  :||.......||.
 Frog   322 LYLYDSVLMLANAFHRKLEDRKWHSMASLNCMRKSTKPWNGGRSMLDTIKKGRITGLTGIMEFKE 386

  Fly   357 Q------RLQINADGQREDFNLEVYNPIIDRVTHIWN--KEFQLVDFEKLRENSTQALKQKRLQN 413
            .      :.:|......|.|..:|      |....|:  |.|.....||...|..|.|..|.:..
 Frog   387 AGANPHVQFEILGTSYSETFGKDV------RRLATWDSMKGFNGSLQEKPLNNDLQGLTLKVVTV 445

  Fly   414 KEDFSQKPIRYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRD 478
            .|:    |........:|:|                :|::|::::::..|:....|.:......|
 Frog   446 LEE----PFVMVAENILGQP----------------KRYKGFSIEILDELSNRLGFKYEIYQAPD 490

  Fly   479 NKYGSYDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPKA 543
            .||| :..:...|:|:|.:||:..|.|.|..:|||..|.:|||||..::...:.|| .|:|..:.
 Frog   491 GKYG-HQLSNGSWNGMIGELINKRADIAISAITITPERENVVDFTKRYLDYSVGIL-IKKPEERI 553

  Fly   544 DIYAFLNPYNAEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVENVNREMERQNIWH-LSNALWL 607
            :|::...|::..||..:...:.:....:....||      |.|...|.....|:... |.:|:|:
 Frog   554 NIFSLFAPFDFAVWACIAAVIPVVGVLIFVLNRI------QAVRAQNSSQTSQSTSSTLHSAIWI 612

  Fly   608 VLGSMLNQGCDLLPRGLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNK 672
            |.|:.:.||.:.....:.||::...||:|.|::..:|.|.||||:|.|::...|.:..||..|..
 Frog   613 VYGAFVQQGGESAANSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLAKQVD 677

  Fly   673 VQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNN---------EEGVDRVKLSKGTY 728
            :.:||::..:...|| :|..| |.:..::..:.......|||         .||:.:.|  :|.|
 Frog   678 LPYGTVKDSSVYEYF-KSKGT-NTLVQDRTFAELWRTIGKNNGSDNCVSSPSEGIRKAK--RGNY 738

  Fly   729 AFLMETTNLQY--YVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRN 791
            |||.:.|.::|  .....|.:...|.:...|.||||:...:.:|...|..||...:.|.|..|:.
 Frog   739 AFLWDVTVVEYAALTDDECSVAVTGNTISSKGYGIALQHGSPYRDIFSQRILEFQDSGRLDVLKE 803

  Fly   792 KWFNSNESTCD--SNVPTIDDGQ-FDMDSVGGLFVVLIVGVVVGLVIGVAEFLWHVQRI---SVK 850
            ||: .....||  |:....:||: ..:.|..|:|.:|.:|:::..::...|..|:..|.   |.|
 Frog   804 KWW-PRTGRCDLNSHNNAQNDGKALKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCRQDSPK 867

  Fly   851 EK---------------IPPMLALKAEFYFVIRFWL---------TRKPLHTYRQSRDSTS---- 887
            |.               |...:|.|......|....         |.:||..|:.::.|.:
 Frog   868 EDKEVNLEQVHRRLNSLIDEDMAHKQISTASIEISALEIGGMPSQTLEPLREYQSTQLSVTTFLP 932

  Fly   888 --TGYSSLEQITSASSA 902
              ||:|....:||..|:
 Frog   933 EQTGHSGGRTLTSIPSS 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	79/431 (18%)
		ANF_receptor	41..378	CDD:279440	69/399 (17%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	102/384 (27%)
		Lig_chan	555..822	CDD:278489	76/281 (27%)
grid1	NP_001096470.1	PBP1_iGluR_delta_1	25..424	CDD:107387	79/430 (18%)
		ANF_receptor	39..400	CDD:279440	66/386 (17%)
		PBP2_iGluR_delta_1	437..807	CDD:270448	106/402 (26%)
		Lig_chan	565..842	CDD:278489	78/287 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000