Protein Alignment GluRIIA and Ir75b

DIOPT Version :9

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 130/636 - (20%)
• Similarity: 237/636 - (37%)
• Gaps: 173/636 - (27%)

  Fly   314 VVLFASSARNVIAAMQPFHPP---NRHCGSSSPWMLGAFI---------VNEM------------ 354
            :.|.|.| :|:....||.|..   |....:.:...||.|:         |.:|
  Fly    31 LALLAQS-KNIFTQFQPLHSDIQLNDDFLNHNILKLGVFLDINCDKSGTVLDMASAKRFFSHRYH 94

  Fly   355 -----KTISEDDVEPHFK------------------TENMKL-DEY--GQRIHFNLEIYKPTVNE 393
                 ::::...:|.|||                  ::|..| |.|  |:::...|.|
  Fly    95 WLIYDRSMNFSVLESHFKEAQIFVDADVTYVTHDPFSKNFLLYDVYNKGRQLGGELNI------- 152

  Fly   394 PMMVWTPDNGIKKRLLNLELE---SAGTTQDFSEQRKVYT--------VVTHYEEPY-FMMKE-- 444
                 |.|..|.....|..:|   |...|:...:.||.:|        |||..  |. ..:||
  Fly   153 -----TADREIFCNKTNCRVERYLSELYTRSALQHRKSFTGLTMRATAVVTAL--PLNVSIKEIF 210

  Fly   445 DHENFRGREKYEGYA---VDLISKLSELMEFDYEFMI----VNGNGKYNPETKQWDGIIRKLIDH 502
            |..|.:.|.:.:.||   ......|.::::..::::.    .:||..        .|:|..||..
  Fly   211 DFMNSKYRIQLDTYARLGYQARQPLRDMLDCKFKYIFRDRWSDGNAT--------GGMIGDLILD 267

  Fly   503 HAQIGVCDLTITQMRRSVVDFTVPFMQLGI--SILHYKSPPEPK---NQFAFLEPFAVEVW---- 558
            .|.:.:... |....|::  |..|..:..:  .|..:::|....   :...||:||:..||
  Fly   268 KADLAIAPF-IYSFDRAL--FLQPITKFSVFREICMFRNPRSVSAGLSATEFLQPFSGGVWLTFA 329

  Fly   559 IYMIFAQLIMTLAFVFIARLSYREWLPPNPAIQDPDELENIWNVNNSTWLMVGSIMQQGCDILPR 623
            :.::.|..::.:.|:...|   ::|.|               ::..|..|..|:...||..:.||
  Fly   330 LLLLLAGCLLWVTFILERR---KQWKP---------------SLLTSCLLSFGAGCIQGAWLTPR 376

  Fly   624 GPHMRILTGMWWFFALM-----MLSTYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGS 683
            .     :.|...|||||     |.:.||:.:.:.|.....:|:|::||.|.:.: :..|......
  Fly   377 S-----MGGRMAFFALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLADSN-LDVGIEPTVY 435

  Fly   684 TSLFFSESNDTDYQRAWNQM---KDFNPSAFTSTNKEGVARVRKEKG---------GYAFLMETT 736
            |.::...|.:.|.:..:.:.   ...:|.......:.||..||.::|         ||.|:.: .
  Fly   436 TRIYVETSEEPDVRDLYRKKVLGSKRSPDKIWIPTEAGVLSVRDQEGFVYITGVATGYEFVRK-H 499

  Fly   737 SLTYNIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWK----- 796
            .|.:.|   |:|.:|..: ...|....:...|.|...:.:|.|::.|.|...|.:..|.:
  Fly   500 FLAHQI---CELNEIPLR-DASHTHTVLAKRSPYAELIKLSELRMLETGVHFKHERSWMETKLHC 560

  Fly   797 ---NHNVTCDSYHEVDGDELSIIELGGVFLVLAGGVLIGV-ILGIFEFLWN 843
               ||.|.           :.:.....:|::|.|.:::.: |||: |.:|:
  Fly   561 YQHNHTVA-----------VGLEYAAPLFIILLGAIILCMGILGL-EVIWH 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..404	CDD:107377	26/139 (19%)
		ANF_receptor	46..386	CDD:279440	23/121 (19%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	88/413 (21%)
		Lig_chan	556..828	CDD:278489	61/300 (20%)
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	72/339 (21%)
		Lig_chan	343..585	CDD:278489	59/281 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462587
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740