Protein Alignment GluRIIA and GLR3.3

DIOPT Version :9

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001322169.1
• Gene: GLR3.3 / 840859
• AraportID: AT1G42540
• Length: 933
• Species: Arabidopsis thaliana
• Alignment Length: 1062
• Identity: 212/1062 - (19%)
• Similarity: 375/1062 - (35%)
• Gaps: 334/1062 - (31%)

  Fly     8 IYAFIIIIGFLEGIIALGGDDRNEIT-VGAIFYENE---KEIELSFDQAFREVNN-------MKF 61
            ::.|..:.....|:......::.::. :|:||..:.   |..:::.|:|.::||:       .||
plant     4 LWTFFFLSFLCSGLFRRTHSEKPKVVKIGSIFSFDSVIGKVAKIAIDEAVKDVNSNPDILSGTKF 68

  Fly    62 SELRFVTIKRYMPTNDSFLLQQI-TCELISNGVAAIFGPSSKAASDIVAQIANATGIPHIEYDLK 125
            |    |:::.   :|.|..:..: ....:...:..|.||.....:.:::.:||...:|.:.:.:
plant    69 S----VSMQN---SNCSGFMGMVEALRFMEKDIVGIIGPQCSVVAHMISHMANELRVPLLSFAV- 125

  Fly   126 LEATRQEQLNHQMSINVAPSLSVLSRAYF--------------EIIKSNYEWRTFTLIYETPE-- 174
                            ..|.:|.|...||              ..|...|.|:....::...:
plant   126 ----------------TDPVMSPLQFPYFIRTTQSDLYQMDAIASIVDFYGWKEVIAVFVDDDFG 174

  Fly   175 --GLARLQDLMNIQALNSDYVKLRNLADYADDYRILWK---ETDETFHEQRI------ILDCEPK 228
              |:|.|.|.:..:.|                 ||.:|   ..|...::..|      |:..:|:
plant   175 RNGVAALNDKLASRRL-----------------RITYKAGLHPDTAVNKNEIMNMLIKIMLLQPR 222

  Fly   229 TL-----KEL-LKVSIDFKLQGPFRN--------WFLTHLDTHNSGLRDIYNEDFKANITSVRLK 279
            .:     .|| ..|..:.|..|...|        |..|:||:             .:.:.:.||:
plant   223 IVVIHVYSELGFAVFKEAKYLGMMGNGYVWIATDWLSTNLDS-------------SSPLPAERLE 274

  Fly   280 VVDA----------NPFER---KKTRLTKVDQILGNQTML---PILIYDAVVLFASSARNVIAAM 328
            .:..          :.|:|   |:.|     ::.|....|   .:..||:|:|.|       ..:
plant   275 TIQGVLVLRPHTPDSDFKREFFKRWR-----KMSGASLALNTYGLYAYDSVMLLA-------RGL 327

  Fly   329 QPFHPPNRHCGSSSPWMLGAF-----IVNEMKTISEDDVEPHFKTENMKLDEYGQRI-------- 380
            ..|.....:...|:..||...     :..|..|:.:..       |.:..|..|.|:
plant   328 DKFFKDGGNISFSNHSMLNTLGKSGNLNLEAMTVFDGG-------EALLKDILGTRMVGLTGQLQ 385

  Fly   381 ------------------------------HFNLEIYKP----TVNEPMM---------VWTPDN 402
                                          |..|....|    |..:|.|         :|..:.
plant   386 FTPDRSRTRPAYDIINVAGTGVRQIGYWSNHSGLSTVLPELLYTKEKPNMSTSPKLKHVIWPGET 450

  Fly   403 GIKKRLLNLELESAGTTQDFSEQRKVYTVVTHYEEPYFMMKEDHENFRGREK-YEGYAVDLISKL 466
            ..|.|         |..  ||...|...:.......|   ||.....||.|. ::|:.:|:.:..
plant   451 FTKPR---------GWV--FSNNGKELKIGVPLRVSY---KEFVSQIRGTENMFKGFCIDVFTAA 501

  Fly   467 SELMEFDYEF-MIVNGNGKYNPE---------TKQWDGIIRKLIDHHAQIGVCDLTITQMRRSVV 521
            ..|:.:.... .|..||||.||.         |..:||:            |.|:.|...|..:|
plant   502 VNLLPYAVPVKFIPYGNGKENPSYTHMVEMITTGNFDGV------------VGDVAIVTNRTKIV 554

  Fly   522 DFTVPFMQLGISILHYKSPPEPKNQ--FAFLEPFAVEVWIYMIFAQLIMTLAFVFIARLSYREWL 584
            |||.|:...|:.::   :|.:..|.  :|||.||...:|       .:....|:|:..:   .|:
plant   555 DFTQPYAASGLVVV---APFKKLNSGAWAFLRPFNRLMW-------AVTGCCFLFVGIV---VWI 606

  Fly   585 ---PPNPAIQDPDELENI---WNVNNSTWLMV---GSIMQQGCDILPRGPHMRILTGMWWFFALM 640
               ..|...:.|.:.:.:   | .:.||....   .::...|          |::..:|.|..|:
plant   607 LEHRTNDEFRGPPKRQCVTILW-FSFSTMFFAHRENTVSTLG----------RLVLIIWLFVVLI 660

  Fly   641 MLSTYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGSTSLFFSESNDTDYQRAWNQMKD 705
            :.|:|||:|.:.||..:..|.||.::.|.|:|. ..|...|.     |:||    |.|  |::..
plant   661 INSSYTASLTSILTVQQLSSPIKGIESLRERDD-PIGYQVGS-----FAES----YLR--NELNI 713

  Fly   706 F--------NPSAFTSTNKEGVARVRKEKGGYAFLM-ETTSLTYNIERNCDLTQIGEQIGEKHYG 761
            .        .|.|:....|:|     ..|||.|.:: |...:...:..||....:|::..:..:|
plant   714 SESRLVPLGTPEAYAKALKDG-----PSKGGVAAIVDERPYVELFLSSNCAYRIVGQEFTKSGWG 773

  Fly   762 LAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWKNHNVTCDSYHEVDGDELSIIELGGVFLVLA 826
            .|.|..|....:||.:||:|:|.|:||::.:||...:..|.:: .|::.|.|.:....|:||:..
plant   774 FAFPRDSPLAIDLSTAILELAENGDLQRIHDKWLMKNACTLEN-AELESDRLHLKSFWGLFLICG 837

  Fly   827 GGVLIGVILGIFEFLWNVQNVAVEERVTPWQAFKAELIFALKFWVRKKPMRISSSSDKSSSRRSS 891
            ...|:.:      ||:.||.:.        |.:             |||...:.:.|:..:..||
plant   838 VACLLAL------FLYFVQIIR--------QLY-------------KKPTDDAIARDQQQNHDSS 875

  Fly   892 GSRRSSK---------EKSRSK 904
             |.||::         ||..||
plant   876 -SMRSTRLQRFLSLMDEKEESK 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..404	CDD:107377	80/495 (16%)
		ANF_receptor	46..386	CDD:279440	71/447 (16%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	99/400 (25%)
		Lig_chan	556..828	CDD:278489	69/289 (24%)
GLR3.3	NP_001322169.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100167
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.770