Protein Alignment GluRIIA and GLR3.4

DIOPT Version :10

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_172012.2
• Gene: GLR3.4 / 839268
• AraportID: AT1G05200
• Length: 959
• Species: Arabidopsis thaliana
• Alignment Length: 1033
• Identity: 209/1033 - (20%)
• Similarity: 368/1033 - (35%)
• Gaps: 303/1033 - (29%)

  Fly    30 NEITVGAIF-YEN------EKEIELSFDQAFREVNNMKFSELRFVTIKRYMPTNDS-FLLQQITC 86
            :.:.|||:| |::      :..::.:.|....:.:.:|..:|..:    :..:|.| |:......
plant    59 SSVNVGALFTYDSFIGRAAKPAVKAAMDDVNADQSVLKGIKLNII----FQDSNCSGFIGTMGAL 119

  Fly    87 ELISNGVAAIFGPSSKAASDIVAQIANATGIPHIEYDLKLEATRQEQLNHQMSINVAPSLSVLSR 151
            :|:.|.|.|..||.|...:.:::.:||...:|.:.:.    ||             .|:||.|..
plant   120 QLMENKVVAAIGPQSSGIAHMISYVANELHVPLLSFG----AT-------------DPTLSSLQF 167

  Fly   152 AYF-EIIKSNY-------------EWRTFTLIYETPE----GLARLQDLMNIQALNSDYVKLRNL 198
            .|| ...:::|             .||....|:...|    |::.|.|::         .|.|:.
plant   168 PYFLRTTQNDYFQMHAIADFLSYSGWRQVIAIFVDDECGRNGISVLGDVL---------AKKRSR 223

  Fly   199 ADY-------ADDYRILWKETDETFHEQRI-ILDCEPKTLKELLKVSIDFKLQGPFRNWFLTH-L 254
            ..|       ||...|..........|.|: ::...|.:...:..|:....:......|..|. |
plant   224 ISYKAAITPGADSSSIRDLLVSVNLMESRVFVVHVNPDSGLNVFSVAKSLGMMASGYVWIATDWL 288

  Fly   255 DTHNSGLRDIYNE--DFKANITSVRLKVVDANPFERKKTRLTKVDQILGNQ--TMLPILIYDAVV 315
            .|....:..:.::  |....:.:.|...::::.   |:..:.:...:..|.  ....:..||:|.
plant   289 PTAMDSMEHVDSDTMDLLQGVVAFRHYTIESSV---KRQFMARWKNLRPNDGFNSYAMYAYDSVW 350

  Fly   316 LFASSA-------RNVIAAMQPFHPPNRHCGSSSPWMLGAF-IVNE----MKTI----------- 357
            |.|.:.       .|:..:    :.||.|..:.|...|.|. :.||    ||.|
plant   351 LVARALDVFFRENNNITFS----NDPNLHKTNGSTIQLSALSVFNEGEKFMKIILGMNHTGVTGP 411

  Fly   358 -----SEDDVEPHFKTENMKLDEYGQRI------HFNLE------------------------IY 387
                 ..:.|.|.:  |.:.|:....|.      |..|.                        ||
plant   412 IQFDSDRNRVNPAY--EVLNLEGTAPRTVGYWSNHSGLSVVHPETLYSRPPNTSTANQRLKGIIY 474

  Fly   388 KPTVNEPMMVWT-PDNGIKKRLLNLELESAGTTQDFSEQRKVYTVVTHYEEPYFMMKEDHENFRG 451
            ...|.:|...|. |:||...|:        |.     ..|..||                 ::..
plant   475 PGEVTKPPRGWVFPNNGKPLRI--------GV-----PNRVSYT-----------------DYVS 509

  Fly   452 REK----YEGYAVDLISKLSELMEFDY-EFMIVNGNGKYNPETKQWDGIIRKLIDHHAQIGVCDL 511
            ::|    ..||.:|:.....||:.:.. ...|:.|:||.||   .:|.::.:::..:..:.|.|:
plant   510 KDKNPPGVRGYCIDVFEAAIELLPYPVPRTYILYGDGKRNP---SYDNLVNEVVADNFDVAVGDI 571

  Fly   512 TITQMRRSVVDFTVPFMQLGISIL----HYKSPPEPKNQFAFLEPFAVEVWI----YMIFAQLIM 568
            ||...|...||||.||::.|:.::    ..||.|     ::||:||.:|:|.    :.:|..
plant   572 TIVTNRTRYVDFTQPFIESGLVVVAPVKEAKSSP-----WSFLKPFTIEMWAVTGGFFLFVG--- 628

  Fly   569 TLAFVFIARLSYREWL--PPNPAIQDPDELENIWNVNNSTWLM---VGSIMQQGCDILPRGPHMR 628
              |.|:|....:.:..  ||.      .:|..|:..:.||...   ..::...|          |
plant   629 --AMVWILEHRFNQEFRGPPR------RQLITIFWFSFSTMFFSHRENTVSSLG----------R 675

  Fly   629 ILTGMWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQDLIEQDK---VHFGSMRGGSTSLFFSE 690
            .:..:|.|..|::.|:|||:|.:.||..:..|.|:.:..|:..::   |..|:.   :.:...:|
plant   676 FVLIIWLFVVLIINSSYTASLTSILTIRQLTSRIEGIDSLVTSNEPIGVQDGTF---ARNYLINE 737

  Fly   691 SN-----------DTDYQRAWNQMKDFNPSAFTSTNKEGVARVRKEKGGYAFLMETTSLTYNIER 744
            .|           :..|..|..:          ..|..|||.:..|. .|..::.|.|
plant   738 LNILPSRIVPLKDEEQYLSALQR----------GPNAGGVAAIVDEL-PYIEVLLTNS------- 784

  Fly   745 NCDLTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWKNHNVTCD-SYHEV 808
            ||....:|::.....:|.|....|....::|.:||||||.|||:|:..| |.|:...|. .....
plant   785 NCKFRTVGQEFTRTGWGFAFQRDSPLAVDMSTAILQLSEEGELEKIHRK-WLNYKHECSMQISNS 848

  Fly   809 DGDELSIIELGGVFLVLAGGVLIGVILGIFEFLWNVQNVAVEERVTPWQAFKAELIFALKFWVRK 873
            :..:||:....|:||:..    |...:.:..|.|.|                        ||..:
plant   849 EDSQLSLKSFWGLFLICG----ITCFMALTVFFWRV------------------------FWQYQ 885

  Fly   874 KPMRISSSSDKSS-----SRRSSGSRRSS-------------------KEKSRSKTVS 907
            :.:..|:..:::.     ||...|||..|                   |:||..|..|
plant   886 RLLPESADEERAGEVSEPSRSGRGSRAPSFKELIKVVDKREAEIKEILKQKSSKKLKS 943

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..405	CDD:380605	87/469 (19%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	94/401 (23%)
		Lig_chan	555..828	CDD:459656	67/296 (23%)
GLR3.4	NP_172012.2	PBP1_GABAb_receptor_plant	62..450	CDD:380645	79/426 (19%)
		Lig_chan-Glu_bd	507..591	CDD:463166	24/86 (28%)
		Lig_chan	613..867	CDD:459656	67/300 (22%)