Protein Alignment GluRIIA and ATGLR1.2

DIOPT Version :9

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_199651.1
• Gene: ATGLR1.2 / 834895
• AraportID: AT5G48400
• Length: 867
• Species: Arabidopsis thaliana
• Alignment Length: 1042
• Identity: 190/1042 - (18%)
• Similarity: 365/1042 - (35%)
• Gaps: 323/1042 - (30%)

  Fly     1 MRLC---PVVIYAFIIIIGFLEGIIALG----GDDRNEITVGAI--------------------- 37
            :|:|   |:::...::::.|:....|..    .|.|..:.||.:
plant     2 VRICIQTPILLSFLLVLLFFISNCFASSQNNDDDKRIRVRVGLVLDLGSVEGKIVRSSVSMALSD 66

  Fly    38 FYENEKEIELSFDQAFREVNNMKFSELRFVTIKRYMPTNDSF--LLQQITCELISNGVAAIFGPS 100
            ||:|..:.:.......|:.:......|            ||.  |||       :.||.||.|.:
plant    67 FYDNHNDYKTRLSLLVRDSHGEPLLAL------------DSVVDLLQ-------TEGVQAIIGGN 112

  Fly   101 SKAASDIVAQIANATGIPHIEYDLKLEATRQEQLNHQMSINVAPSLSVLSRAYFEIIKS------ 159
            |...:.::|::.....:|.|            .||..||::::        .|..:|::
plant   113 SLLEAKLLAELGEKARVPVI------------SLNSPMSLSLS--------KYTHLIQATHNSAS 157

  Fly   160 ----------NYEWRTFTLIYETPEGLARLQDLMNIQALNSDYVKLRNLADYADDYRILWKET-- 212
                      .::|.:..|:.|                            |:.|     |:|:
plant   158 EVKGITAFLHGFDWNSVALVLE----------------------------DHDD-----WRESMH 189

  Fly   213 --DETFHEQRI----------------ILDCEPKTLKEL--------LKVSIDFKL--------- 242
              .:.|||..:                ::| ..:.||:|        |...|..:|
plant   190 FMVDHFHENNVHVQSKVAFSVTSSEDSLMD-RLRELKDLGTTVFVVHLSEVIATRLFPCAEKLGM 253

  Fly   243 QGPFRNWFLTHLDT---HNSGLRDIYNE------DFKANITSVRLKVVDANPFERKKTRLTKVDQ 298
            .|....|.||....   |:..:.|:..|      .||:.|...:    :.:.|..:..:...|::
plant   254 MGEGFAWILTSRSMSSFHDQFIDDLTKEAMEGVVGFKSYIPMSK----ELHNFTLRWRKTLPVEE 314

  Fly   299 ILGNQ-TMLPI---LIYDAVVLFASSAR-----NVIAAMQPFHPPNRHCGSSSPWMLGAFIVNEM 354
            :.|:: |.|.|   ..:|.....||:|.     .|.:.:......:|..|.|     |.|.:::|
plant   315 VTGSEITRLSISGVWAHDVAWSLASAAEVTRMPTVTSTLLEAIKESRFKGLS-----GNFQLDDM 374

  Fly   355 KTISEDDVEPHFKTENMKLDEYGQRIHFNLEIYKPTVNEPMMVWTPDNGIKKRLL------NLE- 412
            |.:|:     .|:..|| :....:|:.|               |..:.....|..      |||
plant   375 KLLSD-----KFEIVNM-IGSGERRVGF---------------WNSNGSFSNRRQLSSTHDNLET 418

  Fly   413 -LESAGTTQD-------FSEQRKVYTVVTHYEE-PYFMMKEDHENFRGREKYEGYAVDLISKLSE 468
             :...|:.|.       .|.::|:..:||.... |..|..|...........||:.:::..  :.
plant   419 IIWPGGSAQSPKGRSLRESGRKKLRVLVTSSNRFPRLMKVETDPITHEITIVEGFCIEVFQ--AS 481

  Fly   469 LMEFDYEFMIV---NGNGKYNPETKQWDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQL 530
            :..|:||...:   ||..    .||....:..:...:.|.:|  |:|||..|...||||:|:.::
plant   482 IAPFNYEVEYIRWLNGTN----YTKLAYALHSQKDKYDAAVG--DITITSDRSMYVDFTLPYTEM 540

  Fly   531 GISILHYKSPPEPKNQFAFLEPFAVEVWI----YMIFAQLIMTLAFVFIARLSYREWLPPNPAIQ 591
            |:.|:..|.    ::.:.|.:|....:||    :.:...:|:.|    |.|...:|:
plant   541 GLGIVAAKE----RSMWVFFQPLTPNLWITSAAFFVLTGIIVWL----IERAENKEF-------- 589

  Fly   592 DPDELENIW--NVNNSTWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALMMLSTYTANLAAFLT 654
                 :..|  .:....|....:::....:.|.......::| :|.|..|:::::|||.|.:.:|
plant   590 -----QGSWPQQIGVVIWFGFSTLVYAHREKLQHNLSRFVVT-VWVFAVLILVTSYTATLTSMMT 648

  Fly   655 SNKWQSSIKSLQDLIEQDKVHFGSMRGGSTSLFFSESNDTDYQRAW-----NQMKDFNPSAFTST 714
                   ::.::....:|.|  |.:.|   ||..:.:......||.     |..:|:..:....:
plant   649 -------VQQIRFNANEDYV--GHLSG---SLIANAALTNSSLRAMRLLGLNTSEDYAQALMNKS 701

  Fly   715 NKEGVAR------VRKEKGGYAFLMETTSLTYNIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTN 773
            ....|:.      :..|..|: |||..|..|.|                 .:|.....||:...|
plant   702 VSYIVSELPYLKILLGENPGH-FLMVKTQSTTN-----------------GFGFMFQKGSELAPN 748

  Fly   774 LSVSILQLSERGELQKMKNKWW-KNHNVTCDSYHEVDGDELSIIELGGVFLVLAGGVLIGVILGI 837
            :|..|.:|.....|.:|:.:|: |....|.|.    ..:.:::....|:|::.  ||.....|.:
plant   749 VSREIAKLRTSERLNEMERRWFDKQLPYTTDD----TSNPITLYRFRGLFMIT--GVSFAFALAV 807

  Fly   838 FEFLW---------NVQNVAVEERVTPWQAFKAELIFALKFWVRKKPMRISSSSDKSSSRRSSGS 893
            ...||         |..|:...:|:..::     ::|...  :...|:.:.:...:::.:.:..:
plant   808 LLILWLRERWEILVNSVNIYFSQRLRHFR-----ILFTRT--IHPSPLGLDNPIGENAVQMAQRN 865

  Fly   894 RR 895
            ||
plant   866 RR 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..404	CDD:107377	79/464 (17%)
		ANF_receptor	46..386	CDD:279440	73/412 (18%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	80/391 (20%)
		Lig_chan	556..828	CDD:278489	53/289 (18%)
ATGLR1.2	NP_199651.1	PBP1_GABAb_receptor	41..407	CDD:107361	79/468 (17%)
		ANF_receptor	55..387	CDD:279440	74/419 (18%)
		GluR_Plant	440..770	CDD:270404	79/389 (20%)
		Lig_chan	563..801	CDD:278489	55/291 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I1813
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.920