Protein Alignment GluRIIA and GLR3.5

DIOPT Version :10

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001324013.1
• Gene: GLR3.5 / 817800
• AraportID: AT2G32390
• Length: 953
• Species: Arabidopsis thaliana
• Alignment Length: 1067
• Identity: 213/1067 - (19%)
• Similarity: 383/1067 - (35%)
• Gaps: 357/1067 - (33%)

  Fly    30 NEITVGAIF-YEN--EKEIELSFDQAFREVNN----MKFSELRFVTIKRYMPTNDS-FLLQQITC 86
            :.:.|||:| |::  .:..:|:|..|..::|.    ::.::|..|    :..||.| |:......
plant    46 SSVNVGALFTYDSFIGRAAKLAFVAAIEDINADQSILRGTKLNIV----FQDTNCSGFVGTMGAL 106

  Fly    87 ELISNGVAAIFGPSSKAASDIVAQIANATGIPHIEYDLKLEATRQEQLNHQMSINVAPSLSVLSR 151
            :|:.|.|.|..||.|.....|::.:||...:|.:.:    .||             .|:||.|..
plant   107 QLMENKVVAAIGPQSSGIGHIISHVANELHVPFLSF----AAT-------------DPTLSSLQY 154

  Fly   152 AYFEIIKSNYEWRTFTLIYETPEGLARLQDLMNIQALNSDYVKLRNLADYADDYRILWKETDETF 216
            .||                              ::...:||.::..:.|:...:|  |:|....|
plant   155 PYF------------------------------LRTTQNDYFQMNAITDFVSYFR--WREVVAIF 187

  Fly   217 HEQR-------IILDCEPKTLKELLKVSIDFKLQGPFRNWFLTHLDTHNSGLRDIYNEDFKANIT 274
            .:..       ::.|...|.     :..|.:|...|        ....||.:.|:.   ...|:.
plant   188 VDDEYGRNGISVLGDALAKK-----RAKISYKAAFP--------PGADNSSISDLL---ASVNLM 236

  Fly   275 SVRLKVVDANPFERKKTRLTKVDQILGNQTMLPILIYDAVVLFASSARNVIAAMQPFHPPNRHCG 339
            ..|:.||..||  .....:..|.:.||......:.|....:|.|      :.:|:|..|
plant   237 ESRIFVVHVNP--DSGLNIFSVAKSLGMMGSGYVWITTDWLLTA------LDSMEPLDP------ 287

  Fly   340 SSSPWMLGAFIVNEMKTISEDDVEPHFK--------TENMKLDE--------------------- 375
            .:...:.|  :|.......|.|.:..||        .|::|.|:
plant   288 RALDLLQG--VVAFRHYTPESDNKRQFKGRWKNLRFKESLKSDDGFNSYALYAYDSVWLVARALD 350

  Fly   376 ----YGQRIHFNLEIYKPTVNEPMMVWTPDNGIK----------KRLLN--LELESAGTTQDF-- 422
                .|..:.|:        |:|.:..|.|:|||          :|.|.  ||:...|.|...
plant   351 VFFSQGNTVTFS--------NDPSLRNTNDSGIKLSKLHIFNEGERFLQVILEMNYTGLTGQIEF 407

  Fly   423 -SEQRKV---YTVV-------------------------THYEEPYFMMKED------------- 445
             ||:.::   |.::                         |.|.:|.....:|
plant   408 NSEKNRINPAYDILNIKSTGPLRVGYWSNHTGFSVAPPETLYSKPSNTSAKDQRLNEIIWPGEVI 472

  Fly   446 ------------------------HENFRGREK----YEGYAVDLISKLSELMEFDY-EFMIVNG 481
                                    ::|:..::|    .:|:.:|:.....:|:.:.. ...|:.|
plant   473 KPPRGWVFPENGKPLKIGVPNRVSYKNYASKDKNPLGVKGFCIDIFEAAIQLLPYPVPRTYILYG 537

  Fly   482 NGKYNPETKQWDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISIL----HYKSPPE 542
            :||.||   .:|.:|.::..:...:.|.|:||...|...||||.||::.|:.::    ..||.|
plant   538 DGKKNP---SYDNLISEVAANIFDVAVGDVTIITNRTKFVDFTQPFIESGLVVVAPVKGAKSSP- 598

  Fly   543 PKNQFAFLEPFAVEVWIYMIFAQLIMTLAFVFIARLSYREWLPPNPAIQDPDELENIWNVNNSTW 607
                ::||:||.:|:|       .:....|:|:..:.   |:           ||:.:|...
plant   599 ----WSFLKPFTIEMW-------AVTGALFLFVGAVI---WI-----------LEHRFNEEF--- 635

  Fly   608 LMVGSIMQQGCDILPRGPHMR-ILTGMW-------------------------WFFALMML-STY 645
                           |||..| |:|..|                         |.|.:::: |:|
plant   636 ---------------RGPPRRQIITVFWFSFSTMFFSHRENTVSTLGRFVLLVWLFVVLIINSSY 685

  Fly   646 TANLAAFLTSNKWQSSIKSLQDLIEQDK---VHFGSMRGGSTSLFFSESNDTDYQRAW----NQM 703
            ||:|.:.||..:..|.|:.:..||..::   |..|:.                   ||    |::
plant   686 TASLTSILTVQQLTSRIEGMDTLIASNEPIGVQDGTF-------------------AWKFLVNEL 731

  Fly   704 KDFNPSAF--TSTNKEGVARVRK--EKGGYAFLME----TTSLTYNIERNCDLTQIGEQIGEKHY 760
             :..||..  ....:|.::.:::  ..||.|.:::    ..:|..|  .||....:|::.....:
plant   732 -NIAPSRIIPLKDEEEYLSALQRGPRGGGVAAIVDELPYIKALLSN--SNCKFRTVGQEFTRTGW 793

  Fly   761 GLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWK-NHNVTCDSYHEVDGDELSIIELGGVFLV 824
            |.|....|....::|.:||||:|.|:|:|::.||.. :|..|. ...:.:..::|:....|:||:
plant   794 GFAFQRDSPLAVDMSTAILQLAEEGKLEKIRKKWLTYDHECTM-QISDTENYQISVQSFWGLFLI 857

  Fly   825 LAGGVLIGVILGIFEFLWNVQNVAVEE------RVTPWQAFKAELIFALKF-----WVRKKPMRI 878
            ......|.:.|..::..|..|.:..||      |.....:.:.:.:.|:.|     .|.|:...|
plant   858 CGVVWFIALTLFCWKVFWQYQRLRPEESDEVQARSEEAGSSRGKSLRAVSFKDLIKVVDKREAEI 922

  Fly   879 SSS-SDKSSSRRSSGSRRSSKEKSRSK 904
            ... .:|||.:...|  :||.|.|:||
plant   923 KEMLKEKSSKKLKDG--QSSAENSQSK 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..405	CDD:380605	80/419 (19%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	95/485 (20%)
		Lig_chan	555..828	CDD:459656	64/315 (20%)
GLR3.5	NP_001324013.1	PBP1_GABAb_receptor_plant	49..444	CDD:380645	91/487 (19%)
		GluR_Plant	485..828	CDD:270404	89/411 (22%)