Protein Alignment GluRIIA and GLR2.9

DIOPT Version :10

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001325277.1
• Gene: GLR2.9 / 817458
• AraportID: AT2G29100
• Length: 942
• Species: Arabidopsis thaliana
• Alignment Length: 1003
• Identity: 207/1003 - (20%)
• Similarity: 376/1003 - (37%)
• Gaps: 239/1003 - (23%)

  Fly    14 IIGFLEGIIALGGDDRNEITVGAIFYENEKEIELSFDQAFREVNNMKFSELRFVTIKRYMPTNDS 78
            :.|||...:.||.:..:||.||.:       ::|          |..||::...:||  |..:|.
plant    14 VCGFLLMGVGLGQNQTSEIKVGVV-------LDL----------NTTFSKICLTSIK--MAVSDF 59

  Fly    79 F-----LLQQIT-----------------CELI-SNGVAAIFGPSSKAASDIVAQIANATGIPHI 120
            :     .|.::|                 .:|| :..|:||.||.:...:|.:.::||.|.:|.|
plant    60 YADHPNYLTRLTLHVRDSMEDTVQASAAALDLIKTEQVSAIIGPINSMQADFMIKLANKTQVPTI 124

  Fly   121 EYDLKLEATRQEQLNHQMSINVAPSLSVLSRAYF---------------EIIKSNYEWRTFTLIY 170
            .:    .||             :|.|:.:...||               .|.|. :.||....||
plant   125 TF----SAT-------------SPLLTSIKSPYFVRATIDDSSQVRAIASIFKF-FRWRRVVAIY 171

  Fly   171 ---ETPEGLARLQDLMNIQALNSDYVKLRNLADYADDYRILWKETDETFHEQR--IILDCEPKTL 230
               |..||.....    ..||....||...:...|.|..| .||..:....|.  .::..|....
plant   172 VDNEFGEGFMPFL----FDALQDVEVKRSVIPPEAIDDEI-QKELRKLMERQARVFVVHMESSLA 231

  Fly   231 KELLKVSIDFKLQGPFRNWFLTHLDTH-----NSGLRDIYNEDFKANITSVRLKVVDANPFER-- 288
            ..:.:::.|..:......|.:|:..||     |:| |.:...:....:.|...|..:...|..
plant   232 LRVFQIARDIGMMEEGYVWLMTNGMTHMMRHINNG-RSLNTIEGVLGVRSHVPKSKELGDFRLRW 295

  Fly   289 KKTRLTKVDQILGNQTMLPILIYDAVVLFASSARNVIAAMQPFHPPNRHCGSSSPWMLGAFIVNE 353
            |:|...:...:..:..:..:..||::...|.:...              ..:.|.|      .:.
plant   296 KRTFEKENPSMRDDLNVFALWAYDSITALAKAVEK--------------ANTKSLW------YDN 340

  Fly   354 MKTISEDDVEPHFKTE--NMKLDEYG-------QRIHFN-----------------LEIYKPTVN 392
            ..|:|::      :|:  |:.:..||       ..:.||                 .||.....|
plant   341 GSTLSKN------RTDLGNVGVSLYGPSLQKAFSEVRFNGLAGEFKLIDGQLQSPKFEIINFVGN 399

  Fly   393 EPMMV--WTPDNGI------KKRLLNLEL---ESAGTTQDFSEQRKVYTVVTHYEEPYF-MMKED 445
            |..::  |||.:|:      .|:.|...:   :|....:.:....|...|....::.:| .:|..
plant   400 EERIIGFWTPRDGLMDATSSNKKTLGPVIWPGKSKIVPKGWEIPGKKLRVGVPMKKGFFDFVKVT 464

  Fly   446 HENFRGREKYEGYAVDLISKLSELMEFDY----EFMIVNGNGKYN-----PETKQWDGIIRKLID 501
            ......::...|||:::..  :.|.|..|    |::.......||     ...|.||.:
plant   465 INPITNKKTPTGYAIEIFE--AALKELPYLVIPEYVSFESPNNYNNLVYQVYDKTWDAV------ 521

  Fly   502 HHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQFAFLEPFAVEVWIYMIFAQL 566
                  |.|:|||..|....|||:||.:.|:|::......|.|:.:.||||:::|:|:
plant   522 ------VGDITITANRSLYADFTLPFTESGVSMMVPVRDNENKDTWVFLEPWSLELWV------- 573

  Fly   567 IMTLAFVFIARLSYREWL---PPNPAIQDPDELENIWNVNNSTWL----MVGSIMQQGCDILPRG 624
            .....||||   .:..||   ..|...:.|.:    :.:..|.|.    ||.:..:.....|
plant   574 TTGCFFVFI---GFVVWLFEHRVNTDFRGPPQ----YQIGTSLWFSFSTMVFAHRENVVSNL--- 628

  Fly   625 PHMRILTGMWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQDLIE-QDKVHFGSMRGGS----- 683
              .|.:..:|.|..|::..:|||:|.:|||....|.::.::.|||: :|.|.:   :||:
plant   629 --ARFVVVVWCFVVLVLTQSYTASLTSFLTVQSLQPTVTNVNDLIKNRDCVGY---QGGAFVKDI 688

  Fly   684 -TSLFFSESNDTDYQRAWNQMKDFNPSAFTSTNKEGVARVRKEKGGYAFLMETTSLTYNIERNCD 747
             ..|.|.|          :|:|.|:    ::.:.:.:....|.||..|...|...|...:.::|.
plant   689 LLGLGFHE----------DQLKPFD----SAKDADDLLSKGKSKGIAAAFDEVAYLKAILSQSCS 739

  Fly   748 -LTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWKNHNVTCDSYHEVDGD 811
             ...:........:|.|.|..|......|.:||.|::....|:::::|:...|...|....:..:
plant   740 KYVMVEPTFKTGGFGFAFPKNSPLTGEFSRAILNLTQNNVTQQIEDRWFPKKNDCPDPMTALSSN 804

  Fly   812 ELSIIELGGVFLVLAGGVLIGVILGIFEFLWNVQN-VAVEERVTPWQAFKAELIFALKFWVRKKP 875
            .|::....|:||:....:...:::.:..||:..:: :..:...:.|:..|    |..|.:..|.
plant   805 RLNLSSFLGLFLIAGTAISFSLLVFVALFLYEHRHTLGDDSEDSLWRKLK----FLFKIFDEKD- 864

  Fly   876 MRISSSSDKSSSRRSSGSRRSSKEKSRS 903
              ::|.:.|:|:..:..|..:.|..|.|
plant   865 --MNSHTFKNSAIHNISSPMTHKTPSPS 890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..405	CDD:380605	85/455 (19%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	92/394 (23%)
		Lig_chan	555..828	CDD:459656	63/287 (22%)
GLR2.9	NP_001325277.1	PBP1_GABAb_receptor_plant	33..415	CDD:380645	85/450 (19%)
		GluR_Plant	445..788	CDD:270404	91/392 (23%)
		Lig_chan	568..821	CDD:459656	63/288 (22%)