DRSC/TRiP Functional Genomics Resources

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Protein Alignment GluRIIA and Ir7f

DIOPT Version :10

Sequence 1:NP_523484.2 Gene:GluRIIA / 33788 FlyBaseID:FBgn0004620 Length:907 Species:Drosophila melanogaster
Sequence 2:NP_001138177.1 Gene:Ir7f / 7354418 FlyBaseID:FBgn0259188 Length:621 Species:Drosophila melanogaster


Alignment Length:456 Identity:83/456 - (18%)
Similarity:160/456 - (35%) Gaps:103/456 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   430 TVVTHYEEPYFMMKED--HENFRGREKYEGYAVDLISKLSELMEFDYEFM---IVNGNGKYNPET 489
            ||:|.::.|:..:..|  |...||    .|:.:.|:..|:..|.|..|.:   ::..|. |....
  Fly   230 TVLTWHQPPFVELVWDPKHNRSRG----SGFEIQLVEHLARRMNFSLELVNIALLRPNA-YRLAE 289

  Fly   490 KQWDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQFAFLE--- 551
            ...:|.|.||:..:..|.:.....|..|..::  |.|        :.|.|    .|..|.|:   
  Fly   290 GSSEGPIEKLLQRNVNISMGYFRKTARRNQLL--TTP--------MSYYS----ANLVAVLQLER 340

  Fly   552 -----------PFAVEVWIYMIFAQLIMTLAFVFIARLSYREWLPPNPAIQDPDELENIWNVNNS 605
                       ||.:.||:.::.|.||.....:..||....|  .....:|             .
  Fly   341 YRIGSLALLVFPFELSVWMLLLLALLIHLGIHLPSARRGNEE--DGGGGLQ-------------V 390

  Fly   606 TWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQDLIE 670
            ..|::|:.:.:    |||....|.:...|.:.::.:..:|.:.|...:....:.:...||..|:.
  Fly   391 VALLLGAALAR----LPRSWRHRFIAAHWLWASIPLRISYQSLLFHLIRLQLYNTPSFSLDQLLA 451

  Fly   671 QDKVHFGSMRGGSTSLFFSE------------SNDTDYQRAWNQM----KDFNPSAFTSTNKEGV 719
            :.   |..:...:|.....|            |.||.:.  |:.:    ::.|...|...|::  
  Fly   452 EG---FQGICTANTQRLLLEMPQLARDPDSIQSVDTPFD--WDVLNVLTRNRNRKIFAVANQD-- 509

  Fly   720 ARVRKEKGGYAFLMETTSLTYNIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSER 784
                          .|.|..::.........:.:.:..::.|:.:|..|.....:...|.:|...
  Fly   510 --------------VTLSFLHSSAHPNAFHVVKQPVNVEYAGMYMPKHSFLYEKMDDDIRRLDAS 560

  Fly   785 GELQKMKNKWWKNHNVTC----DSYHEVDGDELSIIELGGVFLVLAGGVLIGVILGIFEFLWNVQ 845
            |.:..     |:..:...    :..|......::..:|.|:::|:||..|:..:|...|.|...:
  Fly   561 GFIHA-----WRRASFASVHRKEQVHMTSRRYINHAKLSGIYMVMAGLYLLAGLLFAGEVLLRQR 620

  Fly   846 N 846
            |
  Fly   621 N 621

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GluRIIANP_523484.2 PBP1_iGluR_Kainate 33..405 CDD:380605
PBP2_iGluR_Kainate 426..796 CDD:270432 71/400 (18%)
Lig_chan 555..828 CDD:459656 45/292 (15%)
Ir7fNP_001138177.1 Periplasmic_Binding_Protein_Type_2 231..>358 CDD:473866 31/145 (21%)
Blue background indicates that the domain is not in the aligned region.

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