Protein Alignment GluRIIA and KaiR1D

DIOPT Version :10

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Alignment Length: 866
• Identity: 317/866 - (36%)
• Similarity: 482/866 - (55%)
• Gaps: 90/866 - (10%)

  Fly    32 ITVGAIFYENEKEIELSFDQAFREVNN----MKFSELRFVTIKRYMPTNDSFLLQQITCELISNG 92
            |.:|.:|:..:...||:|.||...:|.    :..|:| ...|:|..|. |||...:..|.|::.|
  Fly    30 IKIGGLFHPADDHQELAFRQAVDRINADRSILPRSKL-VAQIERISPF-DSFHAGKRVCGLLNIG 92

  Fly    93 VAAIFGPSSKAASDIVAQIANATGIPHIE--YDLKLEATRQEQLNHQMSINVAPSLSVLSRAYFE 155
            |||||||.|...:..|..|.:...|||:|  :|.:|   |:|    ...:|:.|..:.||:||.:
  Fly    93 VAAIFGPQSSHTASHVQSICDNMEIPHLENRWDYRL---RRE----SCLVNLYPHPNTLSKAYVD 150

  Fly   156 IIKSNYEWRTFTLIYETPEGLARLQDLMNIQALNSDYVKLRNLADYADDYRILWKETDETFHEQR 220
            |:: ::.|:|||:|||..:|:.|||:|:....:....:.:|.|:| :.|||.|.|:...: .|..
  Fly   151 IVR-HWGWKTFTIIYENNDGIVRLQELLKAHGMTPFPITVRQLSD-SGDYRPLLKQIKNS-AEAH 212

  Fly   221 IILDCEPKTLKELLKVSIDFKLQGPFRNWFLTHLDTHNSGLRDIYNEDFK---ANITSVRL---K 279
            |:|||..:.:.|:||.:....:...:.::.:|.||.|...|     ::|:   .|||..||   |
  Fly   213 IVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNL-----DEFRYGGTNITGFRLINEK 272

  Fly   280 VVDANPFERKKTRLTKVDQ--ILGNQTMLPI-----LIYDAVVLFASSARNVIAAMQ-PFHPPNR 336
            :|.      ...|...:|:  :|.:..:..:     |:||||.|||.:..::..:.| ..||.:
  Fly   273 IVS------DVVRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPIS- 330

  Fly   337 HCGSSSPWMLGAFIVNEMKTISEDDVEPHFKTENMKLDEYGQRIHFNLEIYK--PTVNEPMMVWT 399
             |...|.|..|..::|.||.     ||....|..:|.|..|.|..|.|:|.:  |.....:..|.
  Fly   331 -CDGQSTWQHGFSLINYMKI-----VEMKGLTNVIKFDHQGFRTDFMLDIVELTPAGIRKIGTWN 389

  Fly   400 ---PDNGIKKRLLNLELESAGTTQDFSEQR---------KVYTVVTHYEEPYFMMKEDHENFRGR 452
               || ||            ..|:.||:::         |...|.|....||.|.||......|.
  Fly   390 STLPD-GI------------NFTRTFSQKQQEIEANLKNKTLVVTTILSNPYCMRKESAIPLSGN 441

  Fly   453 EKYEGYAVDLISKLSELMEFDYEFMIV-NGN-GKYNPETKQWDGIIRKLIDHHAQIGVCDLTITQ 515
            :::||||||||.::|:.:.|:|:..:| :|: |..|..|.:|:|:||:|::..|.:.:.|||||.
  Fly   442 DQFEGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITF 506

  Fly   516 MRRSVVDFTVPFMQLGISILHYKSPPEPKNQFAFLEPFAVEVWIYMIFAQLIMTLAFVFIARLSY 580
            .|...||||.|||.||:|||:.|...:|.|.|:||.|.:::|||||..|.|.:::....:|:.:.
  Fly   507 EREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTP 571

  Fly   581 REWLPPNPAIQDP--DELENIWNVNNSTWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALMMLS 643
            .||    ||..|.  :::|:.:.:.|..|..:||:||||||.||:....|::.|:||||.|:|:|
  Fly   572 YEW----PAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMIS 632

  Fly   644 TYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGSTSLFFSESNDTDYQRAWNQMKDFNP 708
            :||||||||||..:..|.|:|.:||.:|.::.:|:::||||:.||.:|..:.|||.|:.|:...|
  Fly   633 SYTANLAAFLTVERMDSPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARP 697

  Fly   709 SAFTSTNKEGVARVRKEKGGYAFLMETTSLTYNIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTN 773
            |.||::|.|||.||.|.||.||||||:||:.|..||||:|||:|..:..|.||:|.|..|.|||.
  Fly   698 SVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVGGMLDTKSYGIATPPNSPYRTA 762

  Fly   774 LSVSILQLSERGELQKMKNKWWKNH--NVTC---DSYHEVDGDELSIIELGGVFLVLAGGVLIGV 833
            ::..||:|.|.|:|..:|.||||..  ...|   .|......:||.:..:||||:||.||:.:..
  Fly   763 INSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVAC 827

  Fly   834 ILGIFEFLWNVQNVAVEERVT 854
            ::.:.||:|..:.||||||::
  Fly   828 VIAVCEFVWKSRKVAVEERLS 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..405	CDD:380605	121/396 (31%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	168/382 (44%)
		Lig_chan	555..828	CDD:459656	124/279 (44%)
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	122/411 (30%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	168/373 (45%)