Protein Alignment GluRIIA and Ir92a

DIOPT Version :9

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Alignment Length: 847
• Identity: 154/847 - (18%)
• Similarity: 248/847 - (29%)
• Gaps: 361/847 - (42%)

  Fly   146 LSVLSRAYFEIIKSNY--EWRTFTLIYE-----TPEGLARLQDL----------MNIQALNSDYV 193
            ||.|.|    ||...|  |:.:..::|.     ||..|..|..|          :.:|.:|..::
  Fly    10 LSQLLR----IIVGQYFAEFPSILIVYNNSASTTPLQLEYLSALELVLRELSKPIRLQWINVAFL 70

  Fly   194 K-LRNLAD---------YADDYRILWKETDETFH--------------EQRIILDCEPKTLKELL 234
            | |.:|.|         ..:.:..:..:|....|              ::|.:..||.::..|||
  Fly    71 KDLNDLEDQVMGALNSSVTEGFITILSQTHHFIHARYYATRNANVRLKDKRYLFLCEDESPAELL 135

  Fly   235 KVSIDFKLQGPFRNWFLTHL------DTHNSGLRDIYNEDFKANITSVRLKVVDANPFERKKTRL 293
            .:.|   ||     ::..||      :|..:|....:.:..:....||..|..|..
  Fly   136 CMDI---LQ-----FYPHHLMVRPGTETAPTGPTGPHPDPRRGGGASVSTKNKDDG--------- 183

  Fly   294 TKVDQILGNQTMLPILIYDAVVLFASSARNVIAAMQPFHPPNRHCGSSSPWMLGAFIVNEMKTIS 358
               :...||:|..|.    ..:.|....:..:.|:          |:....:|.||:.||
  Fly   184 ---EGGAGNKTTSPY----RDINFELWTQKFVGAV----------GNLDALLLDAFLPNE----- 226

  Fly   359 EDDVEPHFKTENMKLDEYGQRIHFNLEIYKPTVNEPMMVWTPDNGIKKRLLNLELESAGTTQDFS 423
                            .:..|:    |:|                 ..:||||
  Fly   227 ----------------TFANRV----ELY-----------------PNKLLNL------------ 242

  Fly   424 EQRKVYTVVTHYEEPYFMMKEDHENFRGREKYEGYAVDLISKLSELMEFDYEFMIVNGNGKYNPE 488
             ||:...|                   |...|..|.:.           :|   :..|.|..:|.
  Fly   243 -QRRSLLV-------------------GSITYVPYTIT-----------NY---VPAGQGDVDPI 273

  Fly   489 TKQW-------DGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQ 546
            ..||       ||....::....|:..|.|.:
  Fly   274 HPQWPNRSLTFDGAEANVMKTFCQVHNCHLRV--------------------------------- 305

  Fly   547 FAFLEPFAVEVW--IY----------MIFAQLI-MTLAFVF------------IARLSYREWLPP 586
                |.:..:.|  ||          .|:.|.: |.:..::            |||.|. ..|.|
  Fly   306 ----EAYGADNWGGIYDNESSDGMLGDIYEQRVEMAIGCIYNWYDGITETSHTIARSSV-TILGP 365

  Fly   587 NPAIQDPDELENIWNVNNSTWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALMMLS---TYTAN 648
            .|| ..|....||...||..||::.|.:              ::.|.:.:| :..:|   .|:..
  Fly   366 APA-PLPSWRTNIMPFNNRAWLVLISTL--------------VICGTFLYF-MKYVSYRLRYSGT 414

  Fly   649 LAAFLTSNKWQSSIKSLQDL----IEQ--------------------------DKVHFGSMRGGS 683
            ...|..|.|.:   ||:.|:    |:|                          :.::.|.::...
  Fly   415 QVKFHHSRKLE---KSMLDIFALFIQQPSAPLSFDRFAPRFFLATILCATITLENIYSGQLKSML 476

  Fly   684 TSLFFSESNDTDYQRAWNQMKDFNPSAF-------TSTNKEGVARVRKEKGGYAFLMETTSLT-- 739
            |..|:|...||..:.|.:..|...||..       :....|.:.....|...|::|...:.:.
  Fly   477 TFPFYSAPVDTIEKWAQSGWKWSAPSIIWVHTVQSSDLETEQILARNFEVHDYSYLSNVSFMPNY 541

  Fly   740 -YNIER-NCDLTQIGEQIG----EKHYGLAVPLGSDYRTNLSVSILQLSERG-----ELQKMKNK 793
             :.||| :.....:|:.:.    |....|...|..||...:|:       ||     ||.|
  Fly   542 GFGIERLSSGSLSVGDYVSTEALENRIVLHDDLYFDYTRAVSI-------RGWILMPELNK---- 595

  Fly   794 WWKNHNVTC--------------DSY---------------HEVDG--DELSIIELGGVFLVLAG 827
                |..||              |.|               |:|.|  ..|.:..:.|...|||.
  Fly   596 ----HIRTCQETGLYFHWELEFIDKYMDKKKQEVLMDLANGHKVKGAPQALDVRNIAGALFVLAF 656

  Fly   828 GV 829
            ||
  Fly   657 GV 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..404	CDD:107377	54/304 (18%)
		ANF_receptor	46..386	CDD:279440	52/286 (18%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	80/454 (18%)
		Lig_chan	556..828	CDD:278489	76/380 (20%)
Ir92a	NP_001097845.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462646
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840