Protein Alignment GluRIIA and Ir75c

DIOPT Version :10

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_649013.3
• Gene: Ir75c / 39983
• FlyBaseID: FBgn0261401
• Length: 623
• Species: Drosophila melanogaster
• Alignment Length: 733
• Identity: 141/733 - (19%)
• Similarity: 261/733 - (35%)
• Gaps: 230/733 - (31%)

  Fly   179 LQDLMNIQALNSDYVKLR---NLADYADDYRILWKETDETFHEQRIILDCEPKTLKELLKVSIDF 240
            |.:::|...:.|.|:.::   |||:...:|                 ||.:...|...|.:..|
  Fly    36 LVEMLNQNGIFSQYIDVQNPDNLANVHKEY-----------------LDSDLVRLGVFLDLGCD- 82

  Fly   241 KLQGPFRNWFLTHLDTHNSGLRDIYNEDFKANITSVRLKVVDANPFERKKTRLTKVDQILGNQTM 305
                      ...|.|:.|....:||::
  Fly    83 ----------KAELVTNQSSRARLYNQN------------------------------------- 100

  Fly   306 LPILIYDAVVLFASSARNVIAAMQPFHPPNRHCGSSSPWMLGAFIVNEMKTISEDDVEPHFKTEN 370
            |..|:||       .|.|.....|.|...|....:            ::..:|.:| |..|
  Fly   101 LHWLLYD-------EAGNFTKLTQLFEGANLSLNA------------DVTYVSRED-EERF---- 141

  Fly   371 MKLDEYGQRIHF--NLEIYKPTVNEPMMVWTPDNGIKKRLLNLEL--------ESAGTTQDFSEQ 425
            :..|.|.:..|.  .|.|   ||::.:........:|:.|..|.|        :.:..|...:..
  Fly   142 ILHDVYNKGSHLGGKLNI---TVDQTLQCNRSHCQVKEYLSELHLRPRLQHRMDLSSVTFRLAAL 203

  Fly   426 RKVYTVVTHYEEPYFMMKEDHENFRGREKYEGYAVDLISKL--------SELMEFDYEFMIVNGN 482
            ..|..:.:..||....:..|.::.          :|.||::        .|::.|...::..
  Fly   204 VSVLPINSSEEELLEFLNSDRDSH----------MDSISRIGNRLIMHTQEILGFKLHYIWC--- 255

  Fly   483 GKYNPETKQWDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQF 547
            |.::.: ..:.|.|..|.:..|::  |              |.||:. ..:.|||..|...:.||
  Fly   256 GTWSVQ-DAFGGAIGMLTNESAEL--C--------------TTPFVP-SWNRLHYLHPMTEQAQF 302

  Fly   548 -----------------AFLEPFAVEVWI----YMIFAQLIMTLAFVFIARLSYREWLPPNPAIQ 591
                             .|||||...||.    .:|||.:::.:.|..     .|.|:...
  Fly   303 RAVCMFRTPHNAGIKAAVFLEPFMPSVWFAFAGLLIFAGVLLWMIFHL-----ERHWMQRC---- 358

  Fly   592 DPDELENIWNVNNSTWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALM-----MLSTYTANLAA 651
                |:.|.::.:|..:..|:...||..::|:....|:.     |.|:|     |.:.||:.:.:
  Fly   359 ----LDFIPSLLSSCLISFGAACIQGSYLMPKSAGGRLA-----FIAVMLTSFLMYNYYTSIVVS 414

  Fly   652 FLTSNKWQSSIKSLQDLIEQ------DKVHFGSMRGGSTSLFFSESNDTDYQRAWNQMKDF--NP 708
            .|..:..:|:|:::|.|.:.      |.|.|       |..:...|...|.:..:.|..:.  :|
  Fly   415 TLLGSPVRSNIRTIQQLADSSLDVGFDTVPF-------TKTYLVSSPRPDIRSLYKQKVESKRDP 472

  Fly   709 SAFTSTNKEGVARVRKEKGGYAFLMETTSLTYNIERN------CDLTQIGEQIGEKHYGLAVPLG 767
            ::...:.:|||.||| ::.|:.:..|.:.:.:.:|::      .||.:|..:.....||: |.|.
  Fly   473 NSVWLSPEEGVIRVR-DQPGFVYTSEASFMYHFVEKHYLPREISDLNEIILRPESAVYGM-VHLN 535

  Fly   768 SDYR---TNLSVSILQLSERGELQKMKNKWWKNHNVTCDSYHEVDGDELSIIELG-----GVFLV 824
            |.||   |.|.|.:|:.....:..:..:| .|.|..: :|:         :|::|     .:|:.
  Fly   536 STYRQLLTQLQVRMLETGITSKQSRFFSK-TKLHTFS-NSF---------VIQVGMEYAAPLFIS 589

  Fly   825 LAGGVLIGVILGIFEFLW 842
            |.....:.:::.|.|..|
  Fly   590 LLVAYFLALLILILEICW 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..405	CDD:380605	38/230 (17%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	88/420 (21%)
		Lig_chan	555..828	CDD:459656	66/303 (22%)
Ir75c	NP_649013.3	Lig_chan	328..>508	CDD:459656	44/205 (21%)