Protein Alignment GluRIIA and Ir64a

DIOPT Version :9

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Alignment Length: 893
• Identity: 156/893 - (17%)
• Similarity: 280/893 - (31%)
• Gaps: 330/893 - (36%)

  Fly   223 LDCEPKTLKELLKVSIDFKLQGPFRNWFLTHLDTHNSGLRDIYNEDFK--ANIT-----SVRLKV 280
            |.|:.....|||::.:|:.|..|.|...|      .|.|...:::|:|  ..||     ...|:.
  Fly    11 LSCQGLPEHELLELELDYGLAEPQRTSLL------QSSLILQFSQDYKHIPRITYFTCQKPHLQT 69

  Fly   281 VDANP--------FERKKTRLTKVDQILGNQTMLPILIYDAVVLFASSARNVIAAMQPFHPPNRH 337
            .:..|        |..|..:|.|  .:..::..:.|::.|.:....:|.|       |..|.|..
  Fly    70 PNQIPNAAEHRDAFAAKNFQLIK--SLYESELFVRIVLLDVLAQSPTSGR-------PNRPGNGP 125

  Fly   338 CG----------SSSPWMLGAFIVNEMKTISEDDV------------------------------ 362
            .|          |:|.|:.|...:..::.|:..|:
  Fly   126 TGGFSQTPSQAQSNSEWLEGVLRMEALRQIAVVDLACGAVSRRFLELASAKMLYSEKFHWLLIED 190

  Fly   363 ----------EPHFKTENMKLDEY---GQRI---------------------------------- 380
                      |...|.::.:::|.   ||:|
  Fly   191 FAWHGRTQTAEGSGKRDDGEMEEEEPPGQQIQATDDEDLPSIESFLGGMNLYMNTELTLAKRMSE 255

  Fly   381 --HFNL-EIYKPTVNEPMMV-------WTPDNGIKKRLLNLELESAGTTQ---DFSEQR-KVYTV 431
              |:.| :::.|.:|....|       :||..||:   |:....:..|.:   |....| :...|
  Fly   256 AAHYTLFDVWNPGLNYGGHVNLTEIGSFTPTEGIQ---LHTWFRTTSTVRRRMDMQHARVRCMVV 317

  Fly   432 VTHYEEPYFMMKEDHENFRGREKY------EGYAVDLISK--LSELME----FDYEFMIVNGNGK 484
            ||            ::|..|...|      .|: :|.:::  .:.||.    |::.|::......
  Fly   318 VT------------NKNMTGTLMYYLTHTMSGH-IDTMNRFNFNLLMAVRDMFNWTFVLSRTTSW 369

  Fly   485 YNPETKQWDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILHYKSPP-------- 541
            ...:..::||:|..||.:...||...:.....|...:|         ::...:.|.|
  Fly   370 GYVKNGRFDGMIGALIRNETDIGGAPIFYWLERHKWID---------VAGRSWSSRPCFIFRHPR 425

  Fly   542 -EPKNQFAFLEPFAVEVWIYMIFAQLIMTLAFVFIARLSYREW----------------LPPNPA 589
             ..|::..||:||..:|||.::...::......|:..:   ||                .||...
  Fly   426 STQKDRIVFLQPFTNDVWILIVGCGVLTVFILWFLTTI---EWKLVPHDGSALIKPKGGAPPRHH 487

  Fly   590 IQDPDELENI-------------------------------------W-----NVN--------- 603
            .|...:.|.:                                     |     .:|
  Fly   488 YQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAK 552

  Fly   604 ------------NSTWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALMMLSTYTANLAAFLTSN 656
                        .|....||.|.|||..........|.:......|:..:...|:|::...|...
  Fly   553 QKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLLME 617

  Fly   657 KWQSSIKSLQDLIE--------------------QDKVHFGSMRGGSTSLFFSESNDTDYQRAWN 701
            | ..:||:|.||:.                    :|.|.........||:..::.|:.|.    :
  Fly   618 K-PKTIKTLSDLVHSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEADE----D 677

  Fly   702 QMKDFNPSAFTSTN------------------KEGVAR--VRKEKG-----GYAFLMETTSL--- 738
            :..|.||   .||:                  |:..|.  :..|.|     |:||.::..:.
  Fly   678 EPVDPNP---VSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKI 739

  Fly   739 ---TYNIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWKN--- 797
               |::.:..||||::.....:|...: :...|..|..:|..:.:::|.|.|....|.|...
  Fly   740 IAETFSEQDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPP 803

  Fly   798 --HNVTCDSYHEVDGDELSIIELGGVFLVLAGGVLIGVILGIFEFLWN 843
              ..:.....| ||.|.:|    ..:.::|....:..:|||. |.|::
  Fly   804 CVKKIETSDLH-VDMDTVS----SALLILLFSYAITLMILGT-EILYS 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..404	CDD:107377	49/292 (17%)
		ANF_receptor	46..386	CDD:279440	44/267 (16%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	91/521 (17%)
		Lig_chan	556..828	CDD:278489	68/406 (17%)
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	23/125 (18%)
		Lig_chan	563..828	CDD:278489	55/278 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462617
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840