Protein Alignment GluRIIA and Ir7c

DIOPT Version :9

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001245572.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Alignment Length: 713
• Identity: 141/713 - (19%)
• Similarity: 245/713 - (34%)
• Gaps: 229/713 - (32%)

  Fly   251 LTHLDTHNSGLRDIYN-----EDFKANITSVRLKVVDANPFERKKTRLTK--VDQILGNQT---M 305
            :.|...||..|  :|.     :::....||..|.||.. |..|:..||..  :|..||..:   .
  Fly     1 MLHSAVHNVSL--VYALVWAIDNYYGMATSTPLAVVQF-PTSRESRRLHNDLIDAALGRSSGTGR 62

  Fly   306 LPILIYDAVVLFASSARNVIAAMQPFHPPNRHCGSS-SPWMLGAFIVNEMKTISEDDVEPHFKTE 369
            :..|:.|..|....:..:     .|  ||:...|.. :.|.|             |.:..:|:.|
  Fly    63 IQFLLEDDRVEMTETDTD-----PP--PPSGLTGRPIAIWFL-------------DSLRSYFRLE 107

  Fly   370 NMKLDEYG---QRIHFNLEIYKPTVNEPMMVWTPDNGIK---KRLLNLE-------LESAGTT-- 419
             |.|::.|   :|..|.|.||....::||      ..:|   :||||:.       |:..||.
  Fly   108 -MYLNQLGSPYKRNGFFLVIYTGLEDQPM------ESLKIMFRRLLNMYVLNVNVFLQRDGTVHL 165

  Fly   420 ----------------------QDFSE------------QRKV-------YTVVTHYEEPYFMMK 443
                                  ||.:.            .||:       ..|.|....||.:::
  Fly   166 YTYYPYGPHHCQSSLPVYYTAFQDLAAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRPYVIIE 230

  Fly   444 EDHENFRGREKY--EGYAVDLISKLSELMEFDYEFMIV--NGNGKYNPETKQWDGIIRKLIDHHA 504
            :|.:...||..:  ||.   :...|:|.|.|..:.:..  ...|:..|: ..:.||::.::|
  Fly   231 DDPKTPGGRSIHGIEGL---IFRSLAERMNFTIKLVEQKDKNRGEILPD-GNFTGILKMMVD--- 288

  Fly   505 QIGVCDLTITQMRRSVVDFTVPFM------QLGISILHYKSPP-----------EPKNQFAFLEP 552
              |..:||.           |.||      .|.:....|.|.|           .|..:..  .|
  Fly   289 --GEVNLTF-----------VCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISPMGRLT--RP 338

  Fly   553 FAVEVWIYMIFAQLIMTLAFVFI---------------ARLSYREWLPPNPAIQDPDELENIWNV 602
            |.     |:|::.::::|.|.|:               ..|..|..||          ...:|
  Fly   339 FR-----YIIWSCILVSLIFGFVLICLLKITALPGLRNLVLGRRNRLP----------FMGMW-- 386

  Fly   603 NNSTWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQD 667
               ..|:.|..:..     |:....|.:..||....|::.:.||..|...|...:.:|.||||.:
  Fly   387 ---ASLLGGLALYN-----PQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSE 443

  Fly   668 LIEQDKVHFGSMRGGSTSLFFSESNDTDYQ-RAWNQMKDFNPSAFTSTN-------KEGVARVRK 724
            ::.:                       ||: |....::.....:..:||       :|.:.|:|.
  Fly   444 VLAK-----------------------DYEFRILPALRTIFKDSMPTTNFHAVLSLEESLYRLRD 485

  Fly   725 E--KGGYAFLMETTSLTYNIERNCD---LTQIGEQIGEKHYGLAVPL------GSDYRTNLSVSI 778
            |  .|....|::.|...::.....:   ||.:.:.:      :..||      .|.::..:...|
  Fly   486 EDDPGITVALLQPTVNQFDFRSGPNKRHLTVLPDPL------MTAPLTFYMRPHSYFKRRIDRLI 544

  Fly   779 LQLSERGELQKMKNKWWKNHNVTCDSYHEVDGDELSIIELGGVFLVLAGGVLIGVILGIFEFL 841
            :.:...|.:.:.: |.:.:..........::...|||..|.|:|:..||..|:.:|:.|.|.|
  Fly   545 MAMMSSGIVARYR-KMYMDRIKRVSKRRNLEPKPLSIWRLSGIFVCCAGLYLVALIVFILEIL 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..404	CDD:107377	39/166 (23%)
		ANF_receptor	46..386	CDD:279440	35/148 (24%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	79/431 (18%)
		Lig_chan	556..828	CDD:278489	53/305 (17%)
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	15/65 (23%)
		Lig_chan	343..593	CDD:278489	52/299 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740