Protein Alignment GluRIIA and Ir7b

DIOPT Version :10

• Sequence 1: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_572410.2
• Gene: Ir7b / 31690
• FlyBaseID: FBgn0029965
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 722
• Identity: 123/722 - (17%)
• Similarity: 232/722 - (32%)
• Gaps: 229/722 - (31%)

  Fly   230 LKELLKVSIDFKLQGPFRNWFL-THLDTHNSG--LRDIYNE--------------------DFKA 271
            |.|.|...:.....|.|:..:: ||.::.::|  |.::.::                    ::|.
  Fly    26 LAEALAQVVANSEMGRFKTLYIYTHTNSQSTGGHLEELLDQVLMIVPNNLQARRLLLQQSMEYKP 90

  Fly   272 NITSVRLKVVDANPFERKKTRLTKV-DQILGNQTMLPILIY-----DAV---------VLFASSA 321
            .:.:| |.:||..|      .|:.: .:|...|.:...|||     ||.         .|:..|.
  Fly    91 YVHAV-LALVDGLP------SLSAIYARIRATQDLSHTLIYMSMPTDAYGEEMQATLRFLWRLSV 148

  Fly   322 RNVIAAMQPFHPPNRH--------------CGSSSPWMLGAFIVNEMKTISEDDVEPHFKTENMK 372
            .||...::   ||..|              |...|..::..:.|...:..|:|    :|.:   |
  Fly   149 LNVGVVLR---PPGDHILMVSYFPFSALHGCQVISANVVNRYQVGTKRWASQD----YFPS---K 203

  Fly   373 LDEYGQRIHFNLEIYKPTVNE-PMMVWTPDN-----GIKKRLLNLELESAGTTQDFSEQRKVYTV 431
            |..:     :...:...|..: |.:||.||.     ||:..||....|:...|...
  Fly   204 LGNF-----YGCLLTCATWEDMPYLVWRPDGSGSFVGIEGALLQFMAENLNFTVGL--------- 254

  Fly   432 VTHYEEPYFMMKEDHENFRGREKYEGYAVDLISKLSELMEFDYEFMIVNGNGKYNPETKQWDGII 496
                   |:|.||:                      .|..||       .:|:          |.
  Fly   255 -------YWMNKEE----------------------VLATFD-------ESGR----------IF 273

  Fly   497 RKLIDHHAQIGVCDLTITQMRRSVVDF---TVPFMQLGISILHYKSPPEPKNQFAFLEPFAVEVW 558
            .::..|||...:..........|.:.:   |..||...:.:.:.:|......:.:|  ||...:|
  Fly   274 DEIFGHHADFSLGGFHFKPSAGSEIPYSQSTYYFMSHIMLVTNLQSAYSAYEKLSF--PFTPLLW 336

  Fly   559 IYMIFAQLIMTLAFVFIARLSYREWLPPNP-----AIQDPDELENIWNVNNSTWLMVGSIMQQGC 618
            ..:....::..|..:.:.|..:...||.||     .:.....||:.|
  Fly   337 RAIGLVLILACLLLMLLVRWRHHHELPRNPYYELLVLTMGGNLEDRW------------------ 383

  Fly   619 DILPRGPHMRILTGMWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGS 683
              :|:....|::...|.|..|::.|.|.:.:...|..:..::..:::.:::.|   ||
  Fly   384 --VPQRFPSRLVLLTWLFATLVLRSGYQSGMYQLLRQDTQRNPPQTISEVLAQ---HF------- 436

  Fly   684 TSLFFSESNDTDYQRAWNQMKDFNPSAFT---STNKEGVARVRKEKGGYAFLMETTSLTY----- 740
             ::..:|.|:.   |....:.:..|....   .:..:....:.::.|..|.:...|...|
  Fly   437 -TIQLAEVNEA---RILASLPELRPEQLVYLEGSELQSFPALAQQSGSSARVAILTPYEYFGYFR 497

  Fly   741 ---NIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWKNH---- 798
               .:.|...|  :.|:|..:.....|...|.....|:..|......|.|:    .|.:.:
  Fly   498 KVHPMSRRLHL--VRERIYTQQLAFYVRRHSHLVGVLNKQIQHAHTHGFLE----HWTRQYVSAV 556

  Fly   799 --------NVTCDSYHEVDG---------------------DELSIIELGGVFLVLAGGVLIGVI 834
                    .:...||..:||                     :.||:.||..:|.::....|..|:
  Fly   557 DEKDESVARIASTSYSTLDGIDGDPSLSESEEDQQVAPVRQNVLSMRELAALFWLILWANLGAVV 621

  Fly   835 LGIFEFL 841
            :.:.|.|
  Fly   622 VFVLELL 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..405	CDD:380605	45/232 (19%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	60/388 (15%)
		Lig_chan	555..828	CDD:459656	49/321 (15%)
Ir7b	NP_572410.2	None