DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oscillin and h6pd

DIOPT Version :9

Sequence 1:	NP_001245894.1	Gene:	Oscillin / 33783	FlyBaseID:	FBgn0031717	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_021332932.1	Gene:	h6pd / 569348	ZFINID:	ZDB-GENE-110408-60	Length:	791	Species:	Danio rerio

Alignment Length:	269	Identity:	61/269 - (22%)
Similarity:	109/269 - (40%)	Gaps:	61/269 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TSDSVGKWAAKYVMKRINDFQPSADR------YFVLGLPTGSTPLGMYKELIEFHKQGKVSFQYV 66
            :|:.:..||.:.|.:..:|...:|:.      .|.|.|..||:|:.:.:.|    .....:|.:.
Zfish   552 SSEMISAWAQELVERLASDLLLAAEEAIRREGQFHLALSGGSSPVALLRAL----ALNLYTFPWR 612

  Fly    67 KT--FNMDEYVGLARDHHESYHYF--MWNNFFKHI-----DIEPKNVHIL-------DGNAADLV 115
            .|  :.:||   ....|.||...|  :.:...:||     :|.|..||:.       ||.|
Zfish   613 NTHIWQVDE---RCVPHTESGSNFRSIHDLLLQHIRIPYFNIHPMPVHLTQRLCVEEDGGA---- 670

  Fly   116 AECNKFEDQIRE---AGGVELFIGGIGPDGHIAFNEPGSSLVSRTRVKTLAQDT-LEANA-RFFD 175
               ..:|.:|::   |......:.|:|.|||.|               :|.||| ||::. |...
Zfish   671 ---TLYEKEIQKHVNASSFHYILLGVGQDGHTA---------------SLFQDTKLESDGERLVT 717

  Fly   176 NDMSKV-PKQALTVGVGTVMDSKEVMILITG--AHKAFALYKAIEEGVNHMWTVSAFQQHANTLM 237
            ...|.: |.|.:::....:..::.|.:|:.|  .|:.......| :|.:..:.::..|.:..:|:
Zfish   718 LTESPIKPHQRMSLTFTAINKARRVGVLVMGKSKHELVTQLSRI-KGESSRYPITKVQPNNGSLI 781

  Fly   238 -ICDEDATL 245
             ..|.||.|
Zfish   782 WYIDYDALL 790

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oscillin	NP_001245894.1	SugarP_isomerase	1..253	CDD:294243	61/269 (23%)
h6pd	XP_021332932.1	G6PD_C	43..508	CDD:332184
h6pd	XP_021332932.1	6PGL	561..784	CDD:238694	54/252 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0363
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810