DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oscillin and GNPDA2

DIOPT Version :9

Sequence 1:	NP_001245894.1	Gene:	Oscillin / 33783	FlyBaseID:	FBgn0031717	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_612208.1	Gene:	GNPDA2 / 132789	HGNCID:	21526	Length:	276	Species:	Homo sapiens

Alignment Length:	259	Identity:	200/259 - (77%)
Similarity:	229/259 - (88%)	Gaps:	0/259 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRLVILETSDSVGKWAAKYVMKRINDFQPSADRYFVLGLPTGSTPLGMYKELIEFHKQGKVSFQY 65
            ||||||:..|...:|||||:..||..|:|..||||.|||||||||||.||:|||:||.|.:||:|
Human     1 MRLVILDNYDLASEWAAKYICNRIIQFKPGQDRYFTLGLPTGSTPLGCYKKLIEYHKNGHLSFKY 65

  Fly    66 VKTFNMDEYVGLARDHHESYHYFMWNNFFKHIDIEPKNVHILDGNAADLVAECNKFEDQIREAGG 130
            ||||||||||||.|:|.||||.:|||||||||||:|.|.||||||||||.|||:.||::|:||||
Human    66 VKTFNMDEYVGLPRNHPESYHSYMWNNFFKHIDIDPNNAHILDGNAADLQAECDAFENKIKEAGG 130

  Fly   131 VELFIGGIGPDGHIAFNEPGSSLVSRTRVKTLAQDTLEANARFFDNDMSKVPKQALTVGVGTVMD 195
            ::||:|||||||||||||||||||||||:||||.||:.|||::||.|:||||..|||||||||||
Human   131 IDLFVGGIGPDGHIAFNEPGSSLVSRTRLKTLAMDTILANAKYFDGDLSKVPTMALTVGVGTVMD 195

  Fly   196 SKEVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHANTLMICDEDATLELRVKTVKYFKGIL 259
            ::|||||||||||||||||||||||||||||||||||..|:.:|||||||||||||||||||::
Human   196 AREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTIFVCDEDATLELRVKTVKYFKGLM 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oscillin	NP_001245894.1	SugarP_isomerase	1..253	CDD:294243	194/251 (77%)
GNPDA2	NP_612208.1	SugarP_isomerase	1..253	CDD:381958	194/251 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160241
Domainoid	1	1.000	374	1.000	Domainoid score	I885
eggNOG	1	0.900	-	-		E1_COG0363
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12381
Inparanoid	1	1.050	428	1.000	Inparanoid score	I1740
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62665
OrthoDB	1	1.010	-	-		D1425290at2759
OrthoFinder	1	1.000	-	-		FOG0003116
OrthoInspector	1	1.000	-	-		otm40730
orthoMCL	1	0.900	-	-		OOG6_102139
Panther	1	1.100	-	-	LDO	PTHR11280
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2549
SonicParanoid	1	1.000	-	-		X2086
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800