DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Oscillin and h6pd

DIOPT Version :9

Sequence 1:	NP_001245894.1	Gene:	Oscillin / 33783	FlyBaseID:	FBgn0031717	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_031760646.1	Gene:	h6pd / 100127695	XenbaseID:	XB-GENE-988586	Length:	801	Species:	Xenopus tropicalis

Alignment Length:	284	Identity:	56/284 - (19%)
Similarity:	99/284 - (34%)	Gaps:	97/284 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VGKWAAKYVMKRINDFQPSADR------YFVLGLPTGSTPLGMYKELIEFHKQGKVSFQYVKTF- 69
            |..||.:.:.|...|.|.:|:.      .|.|.|..|||||.:::.|.:.|.    .|.:.:|.
Frog   566 VSNWAEQLIEKLARDIQLAAESAVQHSGVFHLALSGGSTPLALFQRLSKHHH----GFPWKRTHL 626

  Fly    70 ------------------NMDEYVGLARDHHESYHYFMWNNFFKHIDIEPKNVHIL--DGN---- 110
                              |:::|:                  .:|:.:...|:|.:  |.|
Frog   627 WLVDERCVPFTEPDSNFGNIEKYL------------------LQHVRVPYINIHPMPVDRNQRIC 673

  Fly   111 -AADLVAE--CNKFEDQIREAGGVELFIGGIGPDGHIAFNEPGSSLVSRTRVKTLAQDTLEANAR 172
             ..||..|  ..:....:..: ..::.:.|:|.|||.|...||            |||.:|.:..
Frog   674 SEEDLGTEVYAKEISSHVSNS-SFDMVLLGLGNDGHTASIFPG------------AQDGIEGHKF 725

  Fly   173 FFDNDMSKVPKQALTVGVGTVMDSKEVMILI--TGAHKAFALYKAIEE--------GVNH----- 222
            ....:....|.:.:::.:..:..::|:.:|:  .|.|....|....|.        |||.
Frog   726 VLFTESPGKPHRRMSLSLSLINKAREIAVLVLGKGKHDIITLISRAERSPIKWPIFGVNPTFGKL 790

  Fly   223 MWTVSAFQQHANTLMICDEDATLE 246
            :|.:             |.||.|:
Frog   791 VWYI-------------DYDALLK 801

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oscillin	NP_001245894.1	SugarP_isomerase	1..253	CDD:294243	56/284 (20%)
h6pd	XP_031760646.1	PTZ00309	38..518	CDD:240353
h6pd	XP_031760646.1	Glucosamine_iso	570..792	CDD:395940	49/256 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910