DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oscillin and GNPDA1

DIOPT Version :9

Sequence 1:	NP_001245894.1	Gene:	Oscillin / 33783	FlyBaseID:	FBgn0031717	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_005268405.1	Gene:	GNPDA1 / 10007	HGNCID:	4417	Length:	318	Species:	Homo sapiens

Alignment Length:	259	Identity:	196/259 - (75%)
Similarity:	225/259 - (86%)	Gaps:	0/259 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRLVILETSDSVGKWAAKYVMKRINDFQPSADRYFVLGLPTGSTPLGMYKELIEFHKQGKVSFQY 65
            |:|:|||......:|||||:..||..|.|..::||.|||||||||||.||:|||::|.|.:||:|
Human    30 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKY 94

  Fly    66 VKTFNMDEYVGLARDHHESYHYFMWNNFFKHIDIEPKNVHILDGNAADLVAECNKFEDQIREAGG 130
            ||||||||||||.|||.||||.||||||||||||.|:|.|||||||.||.|||:.||::|:.|||
Human    95 VKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGG 159

  Fly   131 VELFIGGIGPDGHIAFNEPGSSLVSRTRVKTLAQDTLEANARFFDNDMSKVPKQALTVGVGTVMD 195
            :|||:||||||||||||||||||||||||||||.||:.|||||||.:::|||..|||||||||||
Human   160 IELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMD 224

  Fly   196 SKEVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHANTLMICDEDATLELRVKTVKYFKGIL 259
            ::|||||||||||||||||||||||||||||||||||..|:.:|||||||||:|||||||||::
Human   225 AREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLM 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oscillin	NP_001245894.1	SugarP_isomerase	1..253	CDD:294243	190/251 (76%)
GNPDA1	XP_005268405.1	nagB	30..287	CDD:179028	195/256 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160240
Domainoid	1	1.000	374	1.000	Domainoid score	I885
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	428	1.000	Inparanoid score	I1740
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62665
OrthoDB	1	1.010	-	-		D1425290at2759
OrthoFinder	1	1.000	-	-		FOG0003116
OrthoInspector	1	1.000	-	-		otm40730
orthoMCL	1	0.900	-	-		OOG6_102139
Panther	1	1.100	-	-	O	PTHR11280
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2549
SonicParanoid	1	1.000	-	-		X2086
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.900