Protein Alignment Lam and Lmntd2

DIOPT Version :10

• Sequence 1: NP_476616.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001334494.1
• Gene: Lmntd2 / 72000
• MGIID: 1919250
• Length: 674
• Species: Mus musculus
• Alignment Length: 651
• Identity: 132/651 - (20%)
• Similarity: 233/651 - (35%)
• Gaps: 176/651 - (27%)

  Fly    33 PSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRET 97
            |.:..::....:||   :....:.:..:|...:.|.:|||....:::::|.        |.|...
Mouse     3 PKSCQESEDKQVSP---APAGVQPDSSDLGSPVGTPVDRVAPSYSQSAKLY--------TSTPMG 56

  Fly    98 TNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYES 162
            .::|.....|.|:.|.|               :.|||:.|     |:.:........|:...|.|
Mouse    57 CSVKQQLAPETLDPRTL---------------RLLWEQRE-----LEIQALRWAVQNGHNARYSS 101

  Fly   163 RANELNNKYNQANADRKKLNEDLNEALKELERLRKQF-EETRKNLEQETLSRVDLENTIQSLREE 226
            ...|:                    |....||||... ..||.:..|:..    |.|.:|.|..|
Mouse   102 ILQEV--------------------AGVPSERLRGMIAPPTRNSKSQDKF----LRNQVQKLTLE 142

  Fly   227 LSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSL---QELRAQYEEQMQINRDEIQS 288
            |..:.:...||       ||            :.:.||:|:|   |:|.|           |:|:
Mouse   143 LKAQKEQAQQE-------KQ------------QLEEKLQQNLWAKQQLEA-----------ELQT 177

  Fly   289 LYEDKIQRLQEAA--ARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLD 351
            ..:..:.:|..::  .|...|...|:|.: :|.|..|..:.:    |.|....:.....||   |
Mouse   178 FQKSCLLQLARSSWVGRVLRSQTGSVEVV-TTEVLRDPSDFS----ESAEIPTSGEGFPLE---D 234

  Fly   352 NDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAY-----DKLLVGEEARLN 411
            .|.....|....|...|     ......|:.|.......:||.|.|..     .|:|  |.:.|.
Mouse   235 VDWNSIAQRYPNLFSNL-----NFYSDQKQSQPPTSETYTLDSEGATKHTEKPTKIL--EWSALP 292

  Fly   412 ITPATNTATVQSFSQS----LRNSTRAT---PSRRTPSAAVKR----KRAVVDESED----HS-- 459
            :...:::...||.:.|    |.:..:.|   ||:.|..|:.::    .|:....:||    ||
Mouse   293 LLDTSSSERTQSDTSSCPIALHSGAKKTTGHPSQGTNLASSEQMQEHTRSFSGYTEDLCKSHSPS 357

  Fly   460 ----VADYYVSASAKGN----------VEIKEIDPEGKFVRLFNKG-SEEVAIGGWQLQRLINEK 509
                |.:.|........          ::|..:....||:|:.|:. :|.:.:||:.||:|:.:
Mouse   358 CSKTVLESYTDLHHPYTRPQLNPFGCCLKIAAVSHREKFIRVINQSQAETIDLGGFVLQQLVRD- 421

  Fly   510 GPSTTYKFHRSVRIEPNGVITVWSADT-KASHEPPSSLVMKSQKWVSADNTRTILLNSEGEAVAN 573
            .|...|:|.....:.|...||||...| :...:.|.:......::.|:....|:|:|.:|:
Mouse   422 FPVCMYRFPPGTLLAPQHHITVWGEGTSRTKKQLPVASGQDPFQFQSSRGCVTVLVNPQGQ---- 482

  Fly   574 LDRIKRIVSQH------TSSSRLSRRRSVTAVD-------------GNEQLYHQQGDPQQSNEKC 619
                  ::|:|      |..|::....:..::|             |.:|.  :...||:...|.
Mouse   483 ------VLSEHQATPCVTLGSKIFTDNTDWSIDCFPLSESEPDVHPGEQQC--RPSSPQKGRAKD 539

  Fly   620 A 620
            |
Mouse   540 A 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_476616.1	Filament	54..409	CDD:459643	75/365 (21%)
		LTD	467..572	CDD:460003	26/116 (22%)
Lmntd2	NP_001334494.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40		7/39 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..282		6/26 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	296..339		9/42 (21%)
		LTD	395..487	CDD:460003	26/102 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	514..573		6/29 (21%)