DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lam and Krt87

DIOPT Version :10

Sequence 1:NP_476616.1 Gene:Lam / 33782 FlyBaseID:FBgn0002525 Length:622 Species:Drosophila melanogaster
Sequence 2:NP_001095145.1 Gene:Krt87 / 681126 RGDID:1583565 Length:495 Species:Rattus norvegicus


Alignment Length:411 Identity:99/411 - (24%)
Similarity:177/411 - (43%) Gaps:92/411 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 GPQPPPPSTHSQTAS--SPLS----P----TRHSRVAEKVELQNLNDRLATYIDRVRNLETENSR 81
            ||.||..:|.|...|  :||:    |    .:|.   ||.:::.||.|.|.:||:||.||.:|  
  Rat    77 GPSPPCITTVSVNESLLTPLNLEIDPNAQCVKHE---EKEQIKCLNSRFAAFIDKVRFLEQQN-- 136

  Fly    82 LTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKK 146
                                     :||||:                    |:..:         
  Rat   137 -------------------------KLLETK--------------------WQFYQ--------- 147

  Fly   147 TKECTTAEGNVR-MYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEE--------- 201
            .::|  .|.|:. ::|.....|..:.....||..:|..:||...:.:|..:|::||         
  Rat   148 NRKC--CESNLEPLFEGYIETLRREAEYVEADSGRLAAELNHVQEAMEGYKKRYEEEVALRATAE 210

  Fly   202 -----TRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSE--IDGRLSSE 259
                 .:|:::...|.:.|||...::|.:|:.|..:::.:|    .|:.....|:  :..::.:.
  Rat   211 NEFVALKKDVDCAYLRKSDLEANAEALTQEIDFLRRLYEEE----TRLLHAHISDTSVIVKMDNS 271

  Fly   260 YDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDA 324
            .|..:...:.|::|||::....:|.|.:|.|..|.:.::....|...:..::.||:......|..
  Rat   272 RDLNMDCVVAEIKAQYDDIASRSRAEAESWYRTKCEEMKATVIRHGETLRRTREEMNELNRIIQR 336

  Fly   325 LNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIK 389
            |.|.|...:...|.|...:.:.|:|.:........::..||..|.:.:::|...|||||::|:.|
  Rat   337 LTAEIENAKCQRAKLETAVAEAEQQGEAALTDARGKLTELEAALQKAKQDMACLLKEYQEVMNSK 401

  Fly   390 VSLDLEIAAYDKLLVGEEARL 410
            :.||:|||.|.:||.|||.||
  Rat   402 LGLDIEIATYRRLLEGEEHRL 422

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LamNP_476616.1 Filament 54..409 CDD:459643 86/371 (23%)
LTD 467..572 CDD:460003
Krt87NP_001095145.1 Keratin_2_head <45..107 CDD:465068 10/29 (34%)
Filament 110..421 CDD:459643 86/375 (23%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.