DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lam and Lmntd1

DIOPT Version :9

Sequence 1:	NP_001245892.1	Gene:	Lam / 33782	FlyBaseID:	FBgn0002525	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	XP_017448329.1	Gene:	Lmntd1 / 500362	RGDID:	1560077	Length:	467	Species:	Rattus norvegicus

Alignment Length:	431	Identity:	89/431 - (20%)
Similarity:	171/431 - (39%)	Gaps:	101/431 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 RRIKQTEYSEID------GRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEA 300
            ||.|...|::|.      .|:.|:|..   :|:.|..:.|..........:.|.....:::.::.
  Rat    20 RRAKSPSYTDISFWVPVMHRVGSQYQF---ESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKT 81

  Fly   301 AARTSNSTHKSIE------------ELRSTRVRIDALNANINELEQANADLN--------ARIRD 345
            ...|.:..|.|:.            .|.|.....:| :||.:::..|...|:        :.:..
  Rat    82 GTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEA-SANFHQIPSAQDSLSPGGLLTSKSNVPS 145

  Fly   346 LERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDI----KVSLDLEIAAYDKLLVGE 406
            ..|                 |:.|..::...|.......||.:    |.|.||     |..::|:
  Rat   146 CSR-----------------KDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDL-----DTYVLGD 188

  Fly   407 EARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSVADYYVSASAKG 471
            .              :.:..||...::...|..:.:..|.:..:|:.|.     ...:||:|. |
  Rat   189 G--------------EDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEE-----VGQFVSSSL-G 233

  Fly   472 NVEIKEIDPEGKFVRLFNKGSE-EVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSAD 535
            :::|.|::.:|.||||.|..:| ||.||.:.||:.:|.:..| .|:|..::.::.:|.:|||:|.
  Rat   234 DIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVS-LYRFPHNITMQASGTVTVWAAA 297

  Fly   536 TKASHEPPSSLVMKSQ-KWVSADNTRTILLNSEGEAVA------------------NLDRIKRIV 581
            ::|..:.|:..|.:.| ::.|:.:..|||....|||:|                  ..:|...::
  Rat   298 SEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVI 362

  Fly   582 SQHTSSSRLSRRRSVTAVDGNEQLYHQQGDPQQSNEKCAIM 622
            ....|........||::::..:|...|:..||    .|:::
  Rat   363 PSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQ----VCSVL 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	34/196 (17%)
		Ax_dynein_light	<283..377	CDD:287215	14/113 (12%)
		LTD	466..572	CDD:279300	38/107 (36%)
Lmntd1	XP_017448329.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0977
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810