DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lam and krt91

DIOPT Version :9

Sequence 1:	NP_001245892.1	Gene:	Lam / 33782	FlyBaseID:	FBgn0002525	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001003445.1	Gene:	krt91 / 445051	ZFINID:	ZDB-GENE-040801-181	Length:	466	Species:	Danio rerio

Alignment Length:	418	Identity:	106/418 - (25%)
Similarity:	197/418 - (47%)	Gaps:	76/418 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 EKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDT 118
            :|..:||||||||:|:::||:||..|:.|.:::                         |:.||..
Zfish   103 DKATMQNLNDRLASYLEKVRSLEKANADLELKI-------------------------RQFLDSK 142

  Fly   119 ARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNE 183
            ....||   |....:....:|:||:    ::.|...|.:.:      .::|....|:..|.|...
Zfish   143 TSPSAR---DYSAYYATISDLQNKI----QDATRINGGIYL------SIDNAKLAADDFRVKYEN 194

  Fly   184 DLNEALKELERLRKQFEE----TRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRI 244
            :|:        :|:..|.    .||.|::.|::|.|||..|:.|:|||.|..:.|.:|:..:|
Zfish   195 ELS--------MRQSVEADIAGLRKVLDELTMTRSDLEMQIEGLKEELIFLKKNHEEELLAAR-- 249

  Fly   245 KQTEYSEIDGRLSSEYDA----KLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQE---AAA 302
                 .::.|::..|.||    .|.:.:.::|..||:....|:.:::..::.|.:.|.:   |:.
Zfish   250 -----GQMSGQVHVEVDAAPQEDLTKVMADIREHYEQVAAKNQRDLEHWFQSKSESLNKEVAAST 309

  Fly   303 RTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKE 367
            .|..||...|.||:.|   :..|...:.......|.|...:.|.:.:..|....:..::..:|::
Zfish   310 ETLQSTKSEITELKRT---LQGLEIELQSQLSMKASLEGTLADTQARYGNMLNGYQMQVGNMEEQ 371

  Fly   368 LIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNST 432
            |::||.::.:|.:|||.|:|||..|::|||.|.:||.||.:|.:.|.:|...:         :::
Zfish   372 LMQLRADLERQGQEYQMLLDIKTRLEMEIAEYRRLLDGEASRSSQTVSTTKTS---------STS 427

  Fly   433 RATPSRRTPSAAVKRKRAVVDESEDHSV 460
            .:.||..:.|...::...:|:|.:|..|
Zfish   428 SSAPSSTSTSTTTRKVVTIVEEVKDGKV 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	96/365 (26%)
		Ax_dynein_light	<283..377	CDD:287215	19/96 (20%)
		LTD	466..572	CDD:279300
krt91	NP_001003445.1	Filament	102..413	CDD:278467	96/365 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000