DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lam and viml

DIOPT Version :9

Sequence 1:	NP_001245892.1	Gene:	Lam / 33782	FlyBaseID:	FBgn0002525	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_957067.1	Gene:	viml / 393746	ZFINID:	ZDB-GENE-040426-1743	Length:	447	Species:	Danio rerio

Alignment Length:	489	Identity:	133/489 - (27%)
Similarity:	232/489 - (47%)	Gaps:	94/489 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SRRAGTATPQPGNTSTPRPPSAGPQPPP----------------PSTHSQTASSPLSPT-----R 48
            ||.:..::.|..::|.....|.|....|                |...|:|....||..     :
Zfish    14 SRSSALSSRQTFSSSARTRVSFGASSSPVIYASKSAKVRSSAAMPRLTSETLDFNLSDALNTEFK 78

  Fly    49 HSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRR 113
            .:|:.||.::|:||||.|:||::||.||.:|..|:.|::..|.   :.::.|.:::|.|:.:.||
Zfish    79 ANRLNEKAQMQSLNDRFASYIEKVRFLEQQNKILSAELEQLRG---QRSSRIADLYEEEMRDLRR 140

  Fly   114 LLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADR 178
            .:|....::.|||:....|.|:.|.||.||.                                |.
Zfish   141 QVDLLTTEKTRAEVMRDNLAEDVERLKEKLQ--------------------------------DE 173

  Fly   179 KKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRR 243
            ....||...::|..          |::::...|:|||||..::||::||:|...:|.:|:.|.:
Zfish   174 MLQREDAENSMKSF----------RQDVDNAALARVDLERKVESLQDELAFLKNLHDEELAELQ- 227

  Fly   244 IKQTEYSEIDG-RLSSEYD-AK--LKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAART 304
                  ::|.| ::..|.| ||  |..:|:::|.|||.....|..|.:..|:.|...|.|||.|.
Zfish   228 ------TQIQGQQVQVEMDMAKPDLTAALRDVRLQYENLASKNIQESEDWYKSKFADLTEAANRN 286

  Fly   305 SNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKELI 369
            :.:...:.:|....|.::.|:...::.|...|..|..::|::|.....:.......|..||:::.
Zfish   287 NEALRLAKQETNEYRRQVQAITCELDALRGTNESLERQMREMEENFGMESSGFQDTIGRLEEDIG 351

  Fly   370 RLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQ-SLRNS-- 431
            .:::||.:.|:|||||:::|::||:|||.|.|||.|||:|:       .|.:.:||. :||.:
Zfish   352 NMKDEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRI-------AAPLPNFSSFNLRETML 409

  Fly   432 -TRATPSRR-TPSAAVK----RKRAVVDES-EDH 458
             ::..|... |....:|    |...|::|| ::|
Zfish   410 ESKLVPENTFTKKVLIKTIETRDGQVINESTQNH 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	106/358 (30%)
		Ax_dynein_light	<283..377	CDD:287215	21/93 (23%)
		LTD	466..572	CDD:279300
viml	NP_957067.1	Filament_head	1..81	CDD:282575	12/66 (18%)
viml	NP_957067.1	Filament	83..391	CDD:278467	106/359 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0977
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810