Protein Alignment Lam and KRT3

DIOPT Version :9

• Sequence 1: NP_001245892.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_024304743.1
• Gene: KRT3 / 3850
• HGNCID: 6440
• Length: 716
• Species: Homo sapiens
• Alignment Length: 435
• Identity: 103/435 - (23%)
• Similarity: 202/435 - (46%)
• Gaps: 76/435 - (17%)

  Fly    15 PGNTSTPR--PPSAGPQPPPPSTHSQTASSPLSPTRHSRVA-----EKVELQNLNDRLATYIDRV 72
            ||:..:|.  .|...|......|.:|:...||:.....::.     |:.:::.||::.|::||:|
Human   240 PGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKV 304

  Fly    73 RNLETENSRLTIE---VQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWE 134
            |.||.:|..|..:   :|....:....|.|::.:||..:...|..||:...:|.|.:.::|.:.:
Human   305 RFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMED 369

  Fly   135 ENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQF 199
            ..|:.|.|.:.:..:.|.||                                          .:|
Human   370 LVEDFKKKYEDEINKRTAAE------------------------------------------NEF 392

  Fly   200 EETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAK- 263
            ...:|:::...:::|:|:..:.:|.:|:.|...::..|:::    .|:..|:....||.:.:..
Human   393 VTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQ----MQSHISDTSVVLSMDNNRSL 453

  Fly   264 -LKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNA 327
             |...:.|:|||||:..|.::.|.::||:.|:..||..|.|..:....:..|:......|..|.|
Human   454 DLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRA 518

  Fly   328 NINELEQANADLNARIRDLERQLDNDRERHGQ--------EIDLLEKELIRLREEMTQQLKEYQD 384
            .|..:::.||:|...|.        :.|:||:        ::..|:..|.:.::::.:.|::||:
Human   519 EIEGVKKQNANLQTAIA--------EAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQE 575

  Fly   385 LMDIKVSLDLEIAAYDKLLVGEEARLN--ITPATNTATVQSFSQS 427
            ||::|::||:|||.|.|||.|||.|::  ...|.:.:.|.|.:.|
Human   576 LMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTS 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	89/367 (24%)
		Ax_dynein_light	<283..377	CDD:287215	22/101 (22%)
		LTD	466..572	CDD:279300
KRT3	XP_024304743.1	Keratin_2_head	<258..282	CDD:318448	4/23 (17%)
		Filament	285..600	CDD:306535	89/368 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910