DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lam and Krt19

DIOPT Version :9

Sequence 1:NP_001245892.1 Gene:Lam / 33782 FlyBaseID:FBgn0002525 Length:622 Species:Drosophila melanogaster
Sequence 2:NP_955792.1 Gene:Krt19 / 360626 RGDID:619936 Length:403 Species:Rattus norvegicus


Alignment Length:383 Identity:102/383 - (26%)
Similarity:171/383 - (44%) Gaps:95/383 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 EKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDT 118
            ||:.:||||||||:|:|:||.||..|..|.:::   ||...::......                
  Rat    83 EKITMQNLNDRLASYLDKVRALEQANGELEVKI---RDWYQKQGPGPFR---------------- 128

  Fly   119 ARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNE 183
                     |..:.::..|:|::|:...|.|.:.....:......|::...|:....|.|..:..
  Rat   129 ---------DYSQYFKTIEDLRDKILGATIENSKIVLQIDNARLAADDFRTKFETEQALRMSVEA 184

  Fly   184 DLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTE 248
            |:|              ..|:.|::.||:|.|||..|::|:|||::..:.|.:||:..|      
  Rat   185 DIN--------------GLRRVLDELTLARTDLEMQIENLKEELAYLKKNHEEEISALR------ 229

  Fly   249 YSEIDGRLSSEYDA----KLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTH 309
             |::.|::|.|.|:    .|.:.|.|:|:|||...:.||.:.::.|..:|..|            
  Rat   230 -SQVGGQVSVEVDSTPGIDLAKILSEMRSQYEAMAEKNRKDAEAWYLTQIDEL------------ 281

  Fly   310 KSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDND--------------RERHGQE 360
                   :|:|.:......||:.|.  .:|..:::|||.:|.:.              ..|:|.:
  Rat   282 -------NTQVAVHTTQIQINKTEV--TELRRKVQDLEIELQSQLSMKAALEGTVAEIEARYGAQ 337

  Fly   361 -------IDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLN 411
                   |..:|.:|..:|.:..:|.:|||.|||||..|:.|||.|..||.|:||..|
  Rat   338 LSHIQGVISSIEVQLSNVRADTERQNQEYQQLMDIKSRLEQEIATYRSLLEGQEAHYN 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LamNP_001245892.1 Filament 54..409 CDD:278467 100/379 (26%)
Ax_dynein_light <283..377 CDD:287215 20/114 (18%)
LTD 466..572 CDD:279300
Krt19NP_955792.1 Head 1..82
Filament 82..393 CDD:278467 100/379 (26%)
Coil 1A 83..118 19/37 (51%)
Linker 1 119..136 1/41 (2%)
Coil 1B 137..228 27/104 (26%)
Linker 12 229..251 7/28 (25%)
Necessary for interaction with PNN. /evidence=ECO:0000250 247..393 46/166 (28%)
Coil 2 252..390 43/158 (27%)
Rod-like helical tail 391..403 3/5 (60%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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