Protein Alignment Lam and Krt84

DIOPT Version :10

• Sequence 1: NP_476616.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001008812.2
• Gene: Krt84 / 315320
• RGDID: 1359402
• Length: 608
• Species: Rattus norvegicus
• Alignment Length: 492
• Identity: 119/492 - (24%)
• Similarity: 226/492 - (45%)
• Gaps: 87/492 - (17%)

  Fly    27 GPQPPPPS--THSQTASSPLS-----PTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTI 84
            ||..|..:  |.:|:..:||:     ..:..:..||.:::.||::.|::||:||.||.:|..|..
  Rat   143 GPSAPAITAVTVNQSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLET 207

  Fly    85 EVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKE 149
            :....:|..... :|::.:|:..:...||.||....|:|       ||..|...:::.|
  Rat   208 KWSFLQDQKCAR-SNLEPLFDNYITSLRRQLDVLVSDQA-------RLQAERNHMQDIL------ 258

  Fly   150 CTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRV 214
                ||..:.||...      ..:|||:                   .:|...:|:::...|::.
  Rat   259 ----EGFKKKYEEEV------VFRANAE-------------------NEFVALKKDVDAAFLNKS 294

  Fly   215 DLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSE--IDGRLSSEYDAKLKQSLQELRAQYEE 277
            |||..:.:|.:|:.|...::.:||    ::.|:..||  :..::.:..|..|...:.|::|||||
  Rat   295 DLEANVDALAQEIEFLKALYLEEI----QLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEE 355

  Fly   278 QMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNAR 342
            ..:.:|.:::|.|:.|.:.::..|.:..::...:.:|:......|..|...|...:...|.|.|.
  Rat   356 VARRSRADVESWYQTKYEEMRVTAGQHCDNLRNTRDEINELTRLIQRLKTEIEHTKAQCAKLEAA 420

  Fly   343 IRDLERQLD---NDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLV 404
            :.:.|:|.:   ||.:   .::..||..|.:.:::|.:||:|||:||:.|::||:||..|.|||.
  Rat   421 VAEAEQQGEAALNDAK---CKLTDLEGALQQAKQDMARQLREYQELMNAKLALDIEIVTYRKLLE 482

  Fly   405 GEEARL-------NITPATNTATVQSFSQS------LRNSTRATPSRRTPSAAVKRKRAVVDESE 456
            |||.|:       ||:.:::...|....:|      |.:|...|.|   .|:.::....::..|.
  Rat   483 GEEIRICEGVGPVNISVSSSRGGVLCGPESLVCGSGLSHSGGVTFS---SSSGIRATGGILASSS 544

  Fly   457 DHSVADYYVSASAKGNVEIKE---------IDPEGKF 484
            ..:..|...|.:..|:|.:.:         :..||.|
  Rat   545 LRAGGDLLSSGTRGGSVLVGDACAPSIPCALPTEGGF 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_476616.1	Filament	54..409	CDD:459643	94/359 (26%)
		LTD	467..572	CDD:460003	5/27 (19%)
Krt84	NP_001008812.2	Keratin_2_head	16..173	CDD:465068	7/29 (24%)
		Filament	177..487	CDD:459643	94/359 (26%)