Protein Alignment Lam and gfap

DIOPT Version :9

• Sequence 1: NP_001245892.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_571448.2
• Gene: gfap / 30646
• ZFINID: ZDB-GENE-990914-3
• Length: 444
• Species: Danio rerio
• Alignment Length: 517
• Identity: 142/517 - (27%)
• Similarity: 230/517 - (44%)
• Gaps: 118/517 - (22%)

  Fly     2 SSKSRRAGTATPQPGNTSTPRPPSAGPQPPPPSTHS-----------QTASSPLSPT-------- 47
            ||..:|.||    ||.:     ||.|    ..|.||           ...||||:.:
Zfish     8 SSYRKRFGT----PGGS-----PSVG----VTSRHSTGRLSLHSSPRHLTSSPLTLSTSRLSLGG 59

  Fly    48 ---------------RHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRET 97
                           |.:|..||||:..||||.|:||::||.||.:|..|..|:...|.   :|.
Zfish    60 ERLDFSADSLLKAQYRETRTNEKVEMMGLNDRFASYIEKVRFLEQQNKMLVAELNQLRG---KEP 121

  Fly    98 TNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYES 162
            :.:.:|::.||.|.||.:|.....:||.||:...|..:...||.:|..:|.....||.|:..:
Zfish   122 SRLGDIYQEELRELRRQVDGLNAGKARLEIERDNLASDLGTLKQRLQDETALRQEAENNLNTF-- 184

  Fly   163 RANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREEL 227
                                                    |:::::..|:||.||..|::|::|:
Zfish   185 ----------------------------------------RQDVDEAALNRVQLERKIEALQDEI 209

  Fly   228 SFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYED 292
            :|..::|.:|:.|.......:...:|..:|.   ..|..:|:|:|||:|.....|..|.:..|..
Zfish   210 NFLKKVHEEEMRELHEQLMAQQVHVDLDVSK---PDLTAALKEIRAQFEAMANSNMQETEEWYRS 271

  Fly   293 KIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERH 357
            |...|.:||.|...:..::.:|....|.:|..|..::..|..:|..|..:::::|.:...:...:
Zfish   272 KFADLTDAANRNGEALRQAKQEANDYRRQIQGLTCDLESLRGSNESLERQLKEMEERFAIETAGY 336

  Fly   358 GQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQ 422
            ...:..||.|:..|:|||.:.|:|||||:::|::||:|||.|.|||.|||:|:       |..||
Zfish   337 QDTVARLEDEIQMLKEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEESRI-------TVPVQ 394

  Fly   423 SFSQSLRNSTRATPSRRTPSAAVKRKRAV-VDESEDHSVADYYVSASAKGNVEIKEIDPEGK 483
            :|: :|:....:..::.||.|.|||...| ..|:.|..:              |||...|.|
Zfish   395 NFT-NLQFRDTSMDTKLTPEAHVKRSIVVRTVETRDGEI--------------IKESTTERK 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	103/354 (29%)
		Ax_dynein_light	<283..377	CDD:287215	22/93 (24%)
		LTD	466..572	CDD:279300	5/18 (28%)
gfap	NP_571448.2	Head	1..84		21/88 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..47		14/51 (27%)
		Filament_head	5..79	CDD:282575	18/83 (22%)
		Filament	80..388	CDD:278467	103/355 (29%)
		Coil 1A	85..116		14/30 (47%)
		Linker 1	117..127		2/12 (17%)
		Coil 1B	128..226		31/139 (22%)
		Linker 12	227..242		2/17 (12%)
		Coil 2A	243..264		8/20 (40%)
		Linker 2	265..268		0/2 (0%)
		Coil 2B	269..389		40/119 (34%)
		Tail	390..444		19/67 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910