Protein Alignment Lam and lmnb2

DIOPT Version :10

• Sequence 1: NP_476616.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_571077.2
• Gene: lmnb2 / 30196
• ZFINID: ZDB-GENE-990630-13
• Length: 583
• Species: Danio rerio
• Alignment Length: 620
• Identity: 235/620 - (37%)
• Similarity: 358/620 - (57%)
• Gaps: 54/620 - (8%)

  Fly    18 TSTPRPPSAGPQPPPPSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRL 82
            |:||...||             |.:||||.|.||:.||.||:.||||||.||||||.||.||.||
Zfish     3 TATPSRASA-------------AQTPLSPARISRLQEKEELRALNDRLAVYIDRVRALELENDRL 54

  Fly    83 TIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKT 147
            ..:|....:..|||.:.||:::||||.:.||:||:|||:||:.:|::.::..|.||:.....||.
Zfish    55 QFKVSEKEEVTTREVSGIKSLYEAELADARRVLDETARERAKLQIELGKVNSELEEVTRNYKKKD 119

  Fly   148 KECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLS 212
            .:...|...::..|::.|:.....|.|.::...|:.:|.:...:|.:........:|.||.|||.
Zfish   120 GDLAAALVRIKDLEAQYNKNEAALNTALSENASLSAELADLKAQLAKAEDAHGVAKKQLEVETLM 184

  Fly   213 RVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEE 277
            ||||||..|||.|||.|:..:..:|:.|:||..:....|:|..:..:|:.||.|:||:||.|:||
Zfish   185 RVDLENRCQSLTEELEFRKSMFDEEVRETRRRHEKRMVEVDSGMQQDYEFKLSQALQDLRKQHEE 249

  Fly   278 QMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNAR 342
            |:||.::|:|..::.|:...:.::.....:...:.|||:...|||:.|:..::.|::..:....|
Zfish   250 QVQIYKEELQHTFKAKLDNAKVSSDLNDKAVLTAREELQEAHVRIEGLSYQLSALQKQASAAEER 314

  Fly   343 IRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEE 407
            ||:||..|.:||:::.:::|..|:|:..:||.|.|||.|||:|:|:|::||:||.||.|||.|||
Zfish   315 IRELEGLLSSDRDKYRRQLDAKEREMAEMRECMQQQLNEYQELLDVKLALDMEINAYRKLLEGEE 379

  Fly   408 ARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSVADYYV----SAS 468
            .||.::|:.::....|      .:|.::.|..:.|:..||||..::||   |.|...|    .|.
Zfish   380 DRLKLSPSPSSRVTVS------RTTASSTSASSRSSRAKRKRVELEES---STAGPKVQISQQAE 435

  Fly   469 AKGNVEIKEIDPEGKFVRLFNKGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWS 533
            |.|:|.|:|||.|||.|.|.|...::.::|.|:|:|.|.: |....|||.....::....:||||
Zfish   436 ASGSVSIEEIDLEGKSVTLRNNSDKDQSLGSWRLKRQIGD-GEEIVYKFSPKFVLKAGQTVTVWS 499

  Fly   534 ADTKASHEPPSSLVMKSQ-KWVSADNTRTILLNSEGEAVANLDRIKRIVSQHTSSSRLSRRRSVT 597
            ||...||.|||.|:.||| .|.:.:|..|:|:||.||.||     ||.|:           :||.
Zfish   500 ADAGMSHSPPSDLLWKSQSSWGTGENILTLLVNSSGEDVA-----KRTVT-----------KSVI 548

  Fly   598 AVD---------GNEQLYHQQGDPQ-QSNEKCAIM 622
            .::         |:|.|:||||||: |...:||:|
Zfish   549 EMENGDDEEGDFGDEDLFHQQGDPKTQRARECAVM 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_476616.1	Filament	54..409	CDD:459643	140/354 (40%)
		LTD	467..572	CDD:460003	46/105 (44%)
lmnb2	NP_571077.2	Filament	25..381	CDD:459643	140/355 (39%)
		LTD	434..542	CDD:460003	49/113 (43%)