Protein Alignment Lam and LMNTD2

DIOPT Version :9

• Sequence 1: NP_001245892.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_016872965.1
• Gene: LMNTD2 / 256329
• HGNCID: 28561
• Length: 722
• Species: Homo sapiens
• Alignment Length: 652
• Identity: 111/652 - (17%)
• Similarity: 210/652 - (32%)
• Gaps: 217/652 - (33%)

  Fly     2 SSKSRRAGTATPQPGNTSTPRPPSAGPQPPPPSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLA 66
            |.:...:|...|..|..:.|..|:..|...|.......::.|           ::.|::|:.|..
Human    79 SEQESVSGHLGPPAGAPAAPETPTCLPDTTPHPAPVVCSADP-----------QLALESLDPRTL 132

  Fly    67 TYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKR 131
            ..:.|.|.||.:..|..|:                |..:|.|.   .:|::.      |.:..||
Human   133 RLLWRQRELEIQALRWAIQ----------------NGEDARLC---HILEEV------AGLPPKR 172

  Fly   132 LWEENEE-LKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERL 195
            .....|: |:|::.|..:|              ..|...:...|.::::|  |.|.|.|.:..|.
Human   173 SSHSQEKLLQNQVQKLIQE--------------LKEQKERAQWALSEQEK--EHLEERLLQTTRT 221

  Fly   196 RKQFEETRKNLEQETLSRVDLEN----------------TIQSLREELSFKDQIHSQEINESRRI 244
            .::.|...:||::..|.::...:                |.::|.:.....:.|.: ...|..|:
Human   222 LQEMEAELQNLQKSCLLQLARSSWVGRMLRSQTGSVEVVTAETLMDPSDLSENIQA-PTGEGFRL 285

  Fly   245 KQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTH 309
            :..:::.:..|..:.: ..::.|.::.:.:...|:....              .|::.:.|...|
Human   286 EDVDWNSVARRYPNLF-TNMEPSSKQKQPRPWPQLDTGS--------------PESSGKHSERHH 335

  Fly   310 KSIE-----------------ELRSTRVRIDALNANIN--------ELEQANADLNARIRDLERQ 349
            |::|                 :..|.|..:.:....|.        ..|||.....:..||.|..
Human   336 KTVEWGSLPCLNTSSSGGADSDSSSCRPGLPSFVQVIGHPPRDHRASSEQALVQAGSYSRDSEDL 400

  Fly   350 LDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITP 414
            ......|||:.:                                                |:..|
Human   401 QKTHSPRHGEPV------------------------------------------------LSPQP 417

  Fly   415 ATNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIKEID 479
            .|:                                      .||...:...|.:   .::|..:.
Human   418 CTD--------------------------------------PDHWSPELLQSPT---GLKIVAVS 441

  Fly   480 PEGKFVRLFNKGSEEVA-IGGWQLQRLINEKG-PSTTYKFHRSVRIEPNGVITVWSADTKASHEP 542
            ...||||:||...|..| :.|..|::|:  :| |...|:|.....:.|...:|||...|:::.:|
Human   442 CREKFVRIFNPSQESTADLSGMVLKQLV--RGFPERLYRFPPGTLLAPRHHVTVWGEATRSAKKP 504

  Fly   543 -PSSLVMKSQKWVSADNTRTILLNSEGE------------AVANLDRIKR-IVSQHTSSSRLSRR 593
             .:|...:....:|.....|:||:.:||            .|...|..:| .||..:.::||..|
Human   505 LRASSSREPVPLLSIRGCATLLLSPKGEVGAGPRWGGRGWGVGVTDAPRRSSVSTGSHAARLRPR 569

  Fly   594 RS 595
            .|
Human   570 GS 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	58/396 (15%)
		Ax_dynein_light	<283..377	CDD:287215	17/118 (14%)
		LTD	466..572	CDD:279300	30/120 (25%)
LMNTD2	XP_016872965.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0977
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810