Protein Alignment Lam and ifd-1

DIOPT Version :9

• Sequence 1: NP_001245892.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001024830.1
• Gene: ifd-1 / 187585
• WormBaseID: WBGene00002057
• Length: 575
• Species: Caenorhabditis elegans
• Alignment Length: 589
• Identity: 130/589 - (22%)
• Similarity: 258/589 - (43%)
• Gaps: 73/589 - (12%)

  Fly    14 QPGNTSTPRP-PSAGPQPPPPSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRNLET 77
            :.|.|:.|.. .|||..    |.::|.|:..:   |.:|..||.|:.:||:|||.|:::||.||.
 Worm    19 ESGRTNLPSGITSAGSL----SAYAQAAAVTI---RDNRDREKREIADLNNRLARYVEKVRFLEA 76

  Fly    78 ENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEE------- 135
            :|..|..::...|......|..:::.::||......|:.:.....:.|:.:|::|..|
 Worm    77 QNRVLENDIGLFRQAAHIHTGKVRDYYDAEKTSLATLVREQEAKVSSAKQNIRKLEPEITTAIRT 141

  Fly   136 ---------------NEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDL 185
                           .|:||:..|               .||....:....|..:.::..|..::
 Worm   142 LASSLEHRQRVRSDKKEQLKHLSD---------------LESETAYIKRLINDCDDEKSHLKTEI 191

  Fly   186 NEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYS 250
            :....|::|:....::.|....:...:..||   ::.|...:|..:....:|||::||....:..
 Worm   192 SRIRGEIKRILALRDKERNGFSRSQTAAQDL---LKKLNATISTHEIAIREEINKARRDSTDKNR 253

  Fly   251 EIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEEL 315
            |.       :..:|..|::|:|.|:|...:..|...:..|:.||..:::.:.:.|.:.:::.||:
 Worm   254 EF-------FHRELHMSMKEIRDQFESDSKKARKTWEEWYKKKITEIKKRSEKFSLTQNQAREEV 311

  Fly   316 RSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKEL--IRLREEMTQQ 378
            ...|..::.|...|::.:.....|:.||.|:  :...|.|....|..|.||||  .|:|:|..:.
 Worm   312 LRIRSLLNELRTKISDADSMTQALSKRIEDM--KFREDEELRMFEQSLTEKELAVTRMRDECAKL 374

  Fly   379 LKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATPSRRTPSA 443
            ..|.:.|::.:::|..|||.|.||:  |:|....|...:...:.:.|..:|.|:....|..:.:.
 Worm   375 SVELETLVENQINLRSEIAHYRKLM--EQAENLRTSYQSDFVIDTPSPLMRTSSHHYGSSYSLNV 437

  Fly   444 AVKRKRAVVDESEDHSVAD----YYVSASAKGNVEIKEIDPEGKFVRLFNKGS-EEVAIGGWQLQ 503
            .....:.|..::.|.|.|.    ....:..||:|:|  |:.:.:.:.:.|..| :...:..|::.
 Worm   438 RDTHNKTVHHDNYDISSASTINTQQFRSYGKGDVKI--IEHKDESIVIENSNSYKSKDLSNWKIN 500

  Fly   504 RLINEKGPST-TYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKSQKWVSADNTRTILLNSE 567
            ..:|  |..| |:....:..|.|:..|::.|  .|:.:.....:..:...:..:.||:|:||:..
 Worm   501 HYVN--GALTGTFILPVATHIHPHEKISIHS--LKSPNLMDDIVATQIYSFDFSKNTKTVLLDDV 561

  Fly   568 GEAV 571
            .:.|
 Worm   562 DDEV 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	86/378 (23%)
		Ax_dynein_light	<283..377	CDD:287215	25/95 (26%)
		LTD	466..572	CDD:279300	23/108 (21%)
ifd-1	NP_001024830.1	Filament	53..404	CDD:278467	87/379 (23%)
		MSP1_C	<167..348	CDD:284802	37/192 (19%)
		LTD	465..569	CDD:279300	23/107 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I1825
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7818
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D204815at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920