Protein Alignment Lam and ifa-3

DIOPT Version :10

• Sequence 1: NP_476616.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_510649.3
• Gene: ifa-3 / 181699
• WormBaseID: WBGene00002051
• Length: 581
• Species: Caenorhabditis elegans
• Alignment Length: 614
• Identity: 164/614 - (26%)
• Similarity: 292/614 - (47%)
• Gaps: 88/614 - (14%)

  Fly    10 TATPQPGNTSTPRPPSAGPQ--PPPPSTHSQTASSPLSP--------TRHSRVAEKVELQNLNDR 64
            |.|....|..|   |::|.:  .....||:.:.:|.|||        .|..|..||.|:..||||
 Worm    20 TVTSSTQNYGT---PASGNRVLKIVTETHTSSVASGLSPYGQGAASTIRDDREREKKEITELNDR 81

  Fly    65 LATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDI 129
            ||:||.:||.|..:|.:|..::...:....:.|.::|.::|.|:.....::.:|.:|...||.:|
 Worm    82 LASYIGKVRFLAAQNRKLEADLNVLQSRFGKSTGSVKIMYEMEITTATNVVKETGKDHEEAEKEI 146

  Fly   130 KRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKK---LNEDLNEALKE 191
            .::.::.:||:.|.::..|  ..||..:::.|.... |:|...:.|..:::   |.|::....||
 Worm   147 GKIKDQLDELRKKFEEAQK--GRAEDRLKIDELLVT-LSNLEAEINLLKRRIALLEEEVARLKKE 208

  Fly   192 LERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRL 256
            ..||..:.:..|..|:||||.|:|.:|.:.::.||:.|           .:|..:||..::..:.
 Worm   209 NFRLTSELQRVRSELDQETLLRIDNQNKVTTILEEIDF-----------MKRGFETELKDLQAQA 262

  Fly   257 SSE--------YDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIE 313
            :.:        :..:|..|::::||:|:..|..||::::|..:.::|.:       :..|::...
 Worm   263 ARDTTSENREYFKNELMNSIRDIRAEYDRFMAGNRNDLESWSQIRVQEI-------NTQTNRQNA 320

  Fly   314 ELRSTRVRIDALNANINELEQANADLNAR-------IRDLERQLDNDRERHGQEIDLLEKELIRL 371
            |:...|..:..|::.::||:..:|:|.||       :.||..||::|:..:...::..:.::.:|
 Worm   321 EINHKRDEVKRLHSQVSELKSKHAELAARNGLLEKQLEDLNYQLEDDQRSYEAALNDKDAQVRKL 385

  Fly   372 REEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNSTRATP 436
            |||....|.|.|.|:|.|.:||.|:..|.::|.|                    .|..|..|...
 Worm   386 REECQALLVELQMLLDTKQTLDGELKVYRRMLEG--------------------NSEENGLRQLV 430

  Fly   437 SRRTPSAAVKRK------RAVVDESEDHSVADYYVSASAKGNVEIKEIDPEGKFVRLFN-KGSEE 494
            .:...::|:..:      |.|..|   ||....| ..||||||.|||:.||||||.|.| ...:|
 Worm   431 EKVVRTSAINEEVDTETMRVVKGE---HSSRTSY-QRSAKGNVSIKEVSPEGKFVILENTHRDKE 491

  Fly   495 VAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKSQKWVSAD-N 558
            ..:|.|:|:|.|:.| ....:.|.....:.|...:.:::.....:: ||..||.:......|. |
 Worm   492 EPLGDWKLKRKIDGK-REIVFTFPSDYILHPVQTVKIFARGNGVAN-PPEVLVFEGDDTFGAGAN 554

  Fly   559 TRTILLNSEGEAVANLDRIKRIVSQHTSS 587
            .:|||.|:.||..|.  .::|...|.|:|
 Worm   555 VQTILYNNSGEERAT--HMQRQSQQTTTS 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_476616.1	Filament	54..409	CDD:459643	97/372 (26%)
		LTD	467..572	CDD:460003	38/106 (36%)
ifa-3	NP_510649.3	solA	<15..>86	CDD:236887	23/68 (34%)
		Filament	71..419	CDD:459643	96/368 (26%)
		LTD	464..570	CDD:460003	39/109 (36%)