Protein Alignment Lam and mua-6

DIOPT Version :10

• Sequence 1: NP_476616.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_510648.1
• Gene: mua-6 / 181698
• WormBaseID: WBGene00003485
• Length: 581
• Species: Caenorhabditis elegans
• Alignment Length: 630
• Identity: 172/630 - (27%)
• Similarity: 299/630 - (47%)
• Gaps: 104/630 - (16%)

  Fly     6 RRAGTATPQPGNTSTPRPPSAGPQPPPPS----------THSQTASSPLSP--------TRHSRV 52
            |.:.|:.|....|.|....:.|   .|.|          |||.:.||.|||        .|.:|.
 Worm     8 RSSITSRPSFNRTVTSSSQNYG---APGSGNRVLKIVTETHSSSVSSGLSPYGQNAASTIRDNRE 69

  Fly    53 AEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDD 117
            .||.|:..||||||:||::||.|:.:|.:|..:::..:....:.|.::|.::|.|:.....::..
 Worm    70 REKKEIMELNDRLASYIEKVRFLDAQNRKLDADLKMLQGRFGKSTGSVKVMYEMEITTATNVVKQ 134

  Fly   118 TARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKK-- 180
            |.:|....|.:|::|.::.:||:.|.::..:  ..||..::: :.....|:|...:.|..:::
 Worm   135 TGKDHGETEKEIRKLQDQLDELRKKFEEAQR--GRAEDRLKI-DDLLVTLSNLEAEINLLKRRIA 196

  Fly   181 -LNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRI 244
             |.|::....||..||..:.:..|..|:||||.|:|.:|.::::.||:.|           .:|.
 Worm   197 LLEEEVARLKKENFRLTSELQRVRIELDQETLLRIDNQNKVKTILEEIDF-----------MKRG 250

  Fly   245 KQTEYSEIDGRLSSE--------YDAKLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAA 301
            .:||..|:..:.:.:        :..:|..:::::||:|::.|..||::::|.|:.::|.:...:
 Worm   251 FETELKELQAQAARDTTSENREYFKNELANAMRDIRAEYDQIMNGNRNDMESWYQLRVQEINTQS 315

  Fly   302 ARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEK 366
            .|.:...:...||::..|.:...|...:::||..|..|..:|.||..||::|:..:...::..:.
 Worm   316 NRQNAENNYQKEEVKRLRNQTSELRQKLSDLESRNLLLEKQIEDLNYQLEDDQRSYEAALNDKDA 380

  Fly   367 ELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATVQSFSQSLRNS 431
            ::.:||||....:.|.|.|:|.|.:||.|:..|.::|.|                .|....||..
 Worm   381 QIRKLREECQALMVELQMLLDTKQTLDGELKVYRQMLEG----------------NSEGNGLRQL 429

  Fly   432 TRATPSRRTPSAAVKRKRAVVDESE---------DHSVADYYVSASAKGNVEIKEIDPEGKFVRL 487
            ..          .|.|..|:.:|::         :||....| ..||||||.|||..||||||.|
 Worm   430 VE----------KVVRTSAINEEADTETMRVVKGEHSSRTSY-QRSAKGNVAIKETSPEGKFVIL 483

  Fly   488 FN-KGSEEVAIGGWQLQRLINEKG------PSTTYKFH--RSVRIEPNGVITVWSADTKASHEPP 543
            .| ..::|..:|.|:|:|.|:.|.      || .|..|  :||:|...|         :....||
 Worm   484 ENTHRAKEEPLGDWKLKRKIDGKREIVFTFPS-DYILHPFQSVKIFARG---------QGIANPP 538

  Fly   544 SSLVMKSQKWVSAD-NTRTILLNSEGEAVANLDRIKRIVSQHTSS 587
            ..|:.:..:..... |.:|||.|::||..|.  .|:|...|.|||
 Worm   539 EVLIFEGDETFGVGANVQTILYNNKGEERAT--HIQRQSQQTTSS 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_476616.1	Filament	54..409	CDD:459643	95/365 (26%)
		LTD	467..572	CDD:460003	42/114 (37%)
mua-6	NP_510648.1	Filament	71..419	CDD:459643	94/361 (26%)
		LTD	464..570	CDD:460003	43/117 (37%)