Protein Alignment Lam and ifa-1

DIOPT Version :9

• Sequence 1: NP_001245892.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001360640.1
• Gene: ifa-1 / 181316
• WormBaseID: WBGene00002050
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 173/628 - (27%)
• Similarity: 312/628 - (49%)
• Gaps: 84/628 - (13%)

  Fly     2 SSKSRRAGTATPQ----------PGNTSTPRPPSAGPQPPPPSTHSQT----------ASSPLSP 46
            |::|.::.|.|..          ...|.:.|.|..|......::..:.          |.|.|||
 Worm    18 SARSEQSSTRTVNYEVIEKTMSFTSTTPSARAPLGGRTTGNVTSQDRMLKIVTEMRSGAGSGLSP 82

  Fly    47 --------TRHSRVAEKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNI 103
                    .|.||..||.|:.:||||||:||::||.||.:|.:|..::...|....::|.||:|:
 Worm    83 FGQNAASTIRDSREREKKEMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNM 147

  Fly   104 FEAELLETRRLLDDTARDRARAEIDIKRLWEENEELKNKLDKKTK--ECTTAEGNVRM-----YE 161
            :|.||::.::|:|:|.:.|...|..:|::.:|..|::.||:..||  |...|:.:..:     .|
 Worm   148 YEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLE 212

  Fly   162 SRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREE 226
            :..:.|..:..|...:.|::.::....|.||:|       .|.:|:||||:|:|.:|.:|:|.||
 Worm   213 AEISLLKRRIAQLEDEVKRIKQENQRLLSELQR-------ARTDLDQETLNRIDYQNQVQTLLEE 270

  Fly   227 LSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQELRAQYEEQMQINRDEIQSLYE 291
            :.|..::|..||.|.:.:...:.:..:...   :..:|..:::::|.:|::...::|::::|.|.
 Worm   271 IDFLRRVHDNEIKELQTLASRDTTPENREF---FKNELSSAIRDIREEYDQVNNVHRNDMESWYR 332

  Fly   292 DKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRER 356
            .|:|.:|..:||.:.....:.||::..|.::..|...:.:||..|:.|..:|::|..||::|:..
 Worm   333 LKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRS 397

  Fly   357 HGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNI------TPA 415
            :...::..:.::.::|||....:.|.|.|:|.|.:||.|||.|.|:|.|||.|..:      ...
 Worm   398 YEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENRAGLKQLVEQVVK 462

  Fly   416 TNTATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESEDHSVADYYVSASAKGNVEIKEIDP 480
            |:..|.::.::::|.....|.||::                        ...||||||.|.|..|
 Worm   463 THAITQETDTETMRVVKGETASRQS------------------------FQRSAKGNVSIHEASP 503

  Fly   481 EGKFVRLFN-KGSEEVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPS 544
            :|||:.|.| ..:::.|||.|:|:|.|:.| ....|...|...:.....:.:: |..:....||.
 Worm   504 DGKFIVLQNTHRAKDEAIGEWKLKRRIDGK-RENVYTLPRDFVLRAGKTLKIF-ARNQGVASPPD 566

  Fly   545 SLVMKSQ-KWVSADNTRTILLNSEGEAVANLDRIKRIVSQHTS 586
            .||..:: .:.|.:|.:|||.|.|||     :|...|..|.|:
 Worm   567 QLVYDAEDSFGSGNNVQTILFNKEGE-----ERATHIQRQSTA 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	108/361 (30%)
		Ax_dynein_light	<283..377	CDD:287215	24/93 (26%)
		LTD	466..572	CDD:279300	38/107 (36%)
ifa-1	NP_001360640.1	Filament	98..450	CDD:365827	108/361 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I1825
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7818
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D204815at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2618
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950