DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lam and Krt13

DIOPT Version :9

Sequence 1:NP_001245892.1 Gene:Lam / 33782 FlyBaseID:FBgn0002525 Length:622 Species:Drosophila melanogaster
Sequence 2:NP_034792.1 Gene:Krt13 / 16663 MGIID:101925 Length:437 Species:Mus musculus


Alignment Length:392 Identity:106/392 - (27%)
Similarity:175/392 - (44%) Gaps:68/392 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 EKVELQNLNDRLATYIDRVRNLETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDT 118
            ||:.:||||||||:|:|:||.||..|:.|.:::   ||...:::.                    
Mouse    96 EKITMQNLNDRLASYLDKVRALEAANADLEVKI---RDWHLKQSP-------------------- 137

  Fly   119 ARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEG-------NVRMYESRANELNNKYNQANA 176
                |..|.|....::..|||:.|:    .|.||...       |.|:   .|::...||.....
Mouse   138 ----ASPERDYSAYYKTIEELRIKI----LEATTDNNRIILEIDNARL---AADDFRLKYENELT 191

  Fly   177 DRKKLNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINES 241
            .|:.:..|:|              ..|:.|::.||::.|||..|:||.|||::..:.|.:|:.|.
Mouse   192 LRQSVEADIN--------------GLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEEEMKEF 242

  Fly   242 RRIKQTEYSEIDGRLSSEYDA----KLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAA 302
            .       :::.|:::.|.||    .|.:.|.|:|.|||...:.||.:.:..::.|...|.:..:
Mouse   243 S-------NQVVGQVNVEMDATPGIDLTRVLAEMREQYEALAEKNRRDAEEWFQTKSAELNKEVS 300

  Fly   303 RTSNSTHKSIEELRSTRVRIDALNANINELEQANADLNARIRDLERQLDNDRERHGQEIDLLEKE 367
            ..:.....|..|:...|..:..|...:.......|.|.:.:.:.|.:.....::....|..:|.:
Mouse   301 SNAEMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLESTLAETECRYALQLQQIQGLISSIEAQ 365

  Fly   368 LIRLREEMTQQLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARL-NITPATNTATVQSFSQSLRNS 431
            |..||.||..|.:||:.|:|||..|:.|||.|..||.|::|:: ......|..|..:.|.| .||
Mouse   366 LSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMTGFNSGGNNTTTSNGSPS-SNS 429

  Fly   432 TR 433
            .|
Mouse   430 GR 431

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LamNP_001245892.1 Filament 54..409 CDD:278467 98/365 (27%)
Ax_dynein_light <283..377 CDD:287215 17/93 (18%)
LTD 466..572 CDD:279300
Krt13NP_034792.1 Head 1..95
Filament 95..407 CDD:278467 98/365 (27%)
Coil 1A 96..131 19/37 (51%)
Linker 1 132..150 3/41 (7%)
Coil 1B 151..242 30/111 (27%)
Linker 12 243..265 5/28 (18%)
Coil 2 266..404 38/137 (28%)
Tail 405..437 8/28 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 408..437 7/25 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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