DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lam and krt98

DIOPT Version :9

Sequence 1:	NP_001245892.1	Gene:	Lam / 33782	FlyBaseID:	FBgn0002525	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	XP_005155788.1	Gene:	krt98 / 100124615	ZFINID:	ZDB-GENE-070822-8	Length:	391	Species:	Danio rerio

Alignment Length:	385	Identity:	103/385 - (26%)
Similarity:	182/385 - (47%)	Gaps:	82/385 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 EKVELQNLNDRLATYIDRVRNLETENSRLTIEVQ---TTRDTVTRETTNIKNIFEAELLETRRLL 115
            :|..:||||.|||:|:::||:||..|:.|..::.   .:.|.||.:.||    |:..:.:.|...
Zfish    49 KKATMQNLNTRLASYLEKVRSLEKANTELEQKISDWYDSHDDVTFDHTN----FQDTIQDLRNEF 109

  Fly   116 DDTARDRARAEIDIKRLWEENEELKNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKK 180
            :..::|.|:..:::     :|.:|                       .|::...||....|.|::
Zfish   110 NTRSQDNAKLILEV-----DNAKL-----------------------AADDFKRKYENELAMRRE 146

  Fly   181 LNEDLNEALKELERLRKQFEETRKNLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIK 245
            :..|..              ..||.|::.:|||.|||..|::|:||.....:.|.:.|
Zfish   147 IEADTG--------------NLRKILDEFSLSRSDLELQIEALKEEFIVLKKNHKENI------- 190

  Fly   246 QTEYSEIDGRLSSEYDA----KLKQSLQELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSN 306
             |...|..|:::...||    .|.|::.|:|..||...|.||:|::|.||.|:..:|:..
Zfish   191 -TLTIETGGQVNVSVDAAPSMDLNQAIDEIRQHYETVTQKNREELESWYESKMAPMQQEV----- 249

  Fly   307 STHKSIEELRSTRVRIDALNANINELE---QANADLNARIRDLERQLDNDRERHGQEIDLLEKEL 368
            |.|.  |||:.:|..:..|.:.:..|:   |.:..:.:   :|:.||::...|:|.::..|:..:
Zfish   250 SNHN--EELQDSRTELKDLTSTLQRLQIELQTHQSMKS---NLDGQLEDTEARYGNQLAGLQTTV 309

  Fly   369 IRLREEMTQ-------QLKEYQDLMDIKVSLDLEIAAYDKLLVGEEARLNITPATNTATV 421
            ..|.::::|       ..:||:.|:|:|..|:.|||.|.:||.||::. |....|.|.||
Zfish   310 SNLEDQLSQFHANIANNKEEYETLLDVKTRLEREIAEYRRLLDGEKSE-NHKLLTKTITV 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	98/371 (26%)
		Ax_dynein_light	<283..377	CDD:287215	23/96 (24%)
		LTD	466..572	CDD:279300
krt98	XP_005155788.1	Filament	50..356	CDD:278467	98/369 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000