Protein Alignment Lam and lmnb2

DIOPT Version :9

• Sequence 1: NP_001245892.1
• Gene: Lam / 33782
• FlyBaseID: FBgn0002525
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_002940085.2
• Gene: lmnb2 / 100038111
• XenbaseID: XB-GENE-490443
• Length: 623
• Species: Xenopus tropicalis
• Alignment Length: 650
• Identity: 233/650 - (35%)
• Similarity: 373/650 - (57%)
• Gaps: 66/650 - (10%)

  Fly    10 TATPQPGNTSTPRPPSAGPQPPPPSTHSQTASSPLSPTRHSRVAEKVELQNLNDRLATYIDRVRN 74
            ||||....||:.:.|:.|            .|:||||||.||:.||.||::||||||.||||||:
 Frog     3 TATPSRSGTSSMQSPARG------------TSTPLSPTRISRLQEKEELRHLNDRLAVYIDRVRS 55

  Fly    75 LETENSRLTIEVQTTRDTVTRETTNIKNIFEAELLETRRLLDDTARDRARAEIDIKRLWEENEEL 139
            ||.||.||.:::....:..|||.:.|||::|:||.:.|::||:|||:|||.:|::.:...:.:||
 Frog    56 LELENDRLMVKISEKEEVTTREVSGIKNLYESELADARKVLDETARERARLQIELGKFRSDLDEL 120

  Fly   140 KNKLDKKTKECTTAEGNVRMYESRANELNNKYNQANADRKKLNEDLNEALKELERLRKQFEETRK 204
            .....||..:.:||:|.:|..|:..:....:...|..:::.|..::.:...:|.:........:|
 Frog   121 TKNYKKKDADLSTAQGRIRDLEALFHRSEAELGTALGEKRSLEAEVADLRAQLSKAEDAHAVAKK 185

  Fly   205 NLEQETLSRVDLENTIQSLREELSFKDQIHSQEINESRRIKQTEYSEIDGRLSSEYDAKLKQSLQ 269
            .||:|||.|||.||.||||:||:.|:..|:.:|..|:|:..:....|:|.....:||:||.|:|.
 Frog   186 QLEKETLMRVDFENRIQSLQEEMDFRKNIYEEESRETRKRHERRIVEVDRGHQYDYDSKLAQALD 250

  Fly   270 ELRAQYEEQMQINRDEIQSLYEDKIQRLQEAAARTSNSTHKSIEELRSTRVRIDALNANINELE- 333
            |||.|::||:::.::|::..|:.|:..::.::.....:.:.:.|||...|:||:.|:..::.|:
 Frog   251 ELRKQHDEQVKMYKEELEQTYQAKLDNIKRSSDHNDKAANTAREELTEARMRIETLSYQLSGLQK 315

  Fly   334 QANADLNARIRDLERQLDNDRERHGQEIDLLEKELIRLREEMTQQLKEYQDLMDIKVSLDLEIAA 398
            |||| ...|||:||:.|.:||:::.:.:|..|||:..:|::|.|||.|||:|:|:|::||:||.|
 Frog   316 QANA-AEDRIRELEQLLSSDRDKYRKLLDSKEKEMAEMRDQMQQQLTEYQELLDVKLALDMEINA 379

  Fly   399 YDKLLVGEEARLNITPATNT-ATVQSFSQSLRNSTRATPSRRTPSAAVKRKRAVVDESED----- 457
            |.|||.|||.||.::|:..: .||...:.|..::||.:.|        |||| |.:|.|:
 Frog   380 YRKLLEGEEERLKLSPSPQSRVTVSRATSSSSSATRTSRS--------KRKR-VEEEYEEGGAGT 435

  Fly   458 -----------HSVAD----------------YYVS--ASAKGNVEIKEIDPEGKFVRLFNKGSE 493
                       |..|.                :::|  |||.|::.|:|||.|||:|.|.|...:
 Frog   436 GLHTGTSLGLSHITASEGSSRTVTSGQGSSTRFHLSQQASATGSISIEEIDLEGKYVHLKNNSDK 500

  Fly   494 EVAIGGWQLQRLINEKGPSTTYKFHRSVRIEPNGVITVWSADTKASHEPPSSLVMKSQK-WVSAD 557
            :.::|.|:|:|.|.|: ....|||.....::....:.::|||...:|.|||.||.|:|. |.:..
 Frog   501 DQSLGNWRLKRKIGEE-EEIVYKFTPKYVLKAGQSVKIYSADAGVAHSPPSILVWKNQSTWGTGS 564

  Fly   558 NTRTILLNSEGEAVANLDRIKRIVSQHTSSSRLSRRRSVTAVDGNEQLYHQQGDPQQSNEKCAIM 622
            |.||.|:|:|.|.||.....|.|:      ..:.......|..|.|.|:||||||:.::..|::|
 Frog   565 NIRTYLVNTEEEEVAVRTVTKSIL------RNVEEEEDEEADFGEEDLFHQQGDPRTTSRGCSVM 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lam	NP_001245892.1	Filament	54..409	CDD:278467	139/355 (39%)
		Ax_dynein_light	<283..377	CDD:287215	29/94 (31%)
		LTD	466..572	CDD:279300	43/108 (40%)
lmnb2	XP_002940085.2	Filament	34..390	CDD:365827	139/356 (39%)
		LTD	474..581	CDD:395746	44/107 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	276	1.000	Domainoid score	I1707
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7818
Inparanoid	1	1.050	391	1.000	Inparanoid score	I1944
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D204815at33208
OrthoFinder	1	1.000	-	-		FOG0001052
OrthoInspector	1	1.000	-	-		mtm9565
Panther	1	1.100	-	-	O	PTHR45721
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X632
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.160