Protein Alignment Hel25E and Ddx39a

DIOPT Version :10

• Sequence 1: NP_723089.1
• Gene: Hel25E / 33781
• FlyBaseID: FBgn0014189
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_446015.2
• Gene: Ddx39a / 89827
• RGDID: 619920
• Length: 427
• Species: Rattus norvegicus
• Alignment Length: 425
• Identity: 349/425 - (82%)
• Similarity: 391/425 - (92%)
• Gaps: 4/425 - (0%)

  Fly     1 MADND---DLLDYEDEEQTETTAVENQEAPKKDVKGTYVSIHSSGFRDFLLKPEILRAIVDCGFE 62
            ||:.|   :||||:::|:.:.........|||||||:|||||||||||||||||:||||||||||
  Rat     1 MAEQDVENELLDYDEDEEPQVPQESTPAPPKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFE 65

  Fly    63 HPSEVQHECIPQAVLGMDILCQAKSGMGKTAVFVLATLQQLEPSDNNTCHVLVMCHTRELAFQIS 127
            |||||||||||||:||||:|||||||||||||||||||||:||. |....|||||||||||||||
  Rat    66 HPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPI-NGQVSVLVMCHTRELAFQIS 129

  Fly   128 KEYERFSKYMPTVKVAVFFGGMAIQKDEETLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFVL 192
            |||||||||||:|||:|||||::|:|||:.||...||:|||||||||||:|::.|||:.:|||||
  Rat   130 KEYERFSKYMPSVKVSVFFGGLSIKKDEDVLKKNCPHVVVGTPGRILALVRSRSLNLRNVKHFVL 194

  Fly   193 DECDKMLEQLDMRRDVQEIFRSTPHGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTLH 257
            |||||||||||||||||||||.|||.||.|||||||||:|||||:|||||||||:||||.|||||
  Rat   195 DECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKEIRPVCRKFMQDPMEVFVDDETKLTLH 259

  Fly   258 GLQQHYVNLKENEKNKKLFELLDVLEFNQVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEE 322
            ||||:||.||::|||:|||:||||||||||||||||||||:||:|||.|||||||.|||||.|||
  Rat   260 GLQQYYVKLKDSEKNRKLFDLLDVLEFNQVVIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEE 324

  Fly   323 RLNRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITF 387
            ||:|||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||:||
  Rat   325 RLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAVTF 389

  Fly   388 VSDENDAKILNEVQDRFDVNISELPEEIDLSTYIE 422
            |||||||||||:|||||:||::|||||||:|||||
  Rat   390 VSDENDAKILNDVQDRFEVNVAELPEEIDISTYIE 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel25E	NP_723089.1	DEADc_DDX39	40..248	CDD:350708	174/207 (84%)
		SF2_C_DEAD	259..388	CDD:350174	114/128 (89%)
Ddx39a	NP_446015.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		12/33 (36%)
		DEADc_DDX39	43..250	CDD:350708	174/207 (84%)
		Q motif	44..72		26/27 (96%)
		DECD box	195..198		2/2 (100%)
		SF2_C_DEAD	261..390	CDD:350174	114/128 (89%)