Protein Alignment Hel25E and DBP5

DIOPT Version :10

• Sequence 1: NP_723089.1
• Gene: Hel25E / 33781
• FlyBaseID: FBgn0014189
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_014689.1
• Gene: DBP5 / 854211
• SGDID: S000005572
• Length: 482
• Species: Saccharomyces cerevisiae
• Alignment Length: 463
• Identity: 128/463 - (27%)
• Similarity: 219/463 - (47%)
• Gaps: 73/463 - (15%)

  Fly    12 DEEQTETTAVENQEAPKKDVKGTYVSI-------------------------------------- 38
            |.|:.:|:.|..:|..|...:.|..||
Yeast    18 DNEKEDTSEVSTKETVKSQPEKTADSIKPAEKLVPKVEEKKTKQEDSNLISSEYEVKVKLADIQA 82

  Fly    39 -------HSSGFRDFLLKPEILRAIVDCGFEHPSEVQHECIPQAVLG--MDILCQAKSGMGKTAV 94
                   .:..|.:..|.||:|:.|....|:.||::|...:|..:..  .:::.|::||.||||.
Yeast    83 DPNSPLYSAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAA 147

  Fly    95 FVLATLQQLEPSDNNTCHVLVMCHTRELA---FQISKEYERFSKYMPTVKVAVFFGGMAIQKDEE 156
            |.|..|.::.|.|.:. ..:.:..:||||   .::.:|..:|:|....:.|...|         |
Yeast   148 FSLTMLTRVNPEDASP-QAICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSF---------E 202

  Fly   157 TLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFVLDECDKMLEQLDMRRDVQEIFRSTPHGKQV 221
            ..|.....::|||||.:|.|:|.|.:.|:.:|.|||||.|.||:|..:......:.|..|...|:
Yeast   203 KNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQL 267

  Fly   222 MMFSATLSKDIRPVCKKFM--QDPMEVYVDDEAKLTLHGLQQHYVNLK-ENEKNKKLFELLDVLE 283
            ::||||.:..:|...||.:  .:.:|:..::   :.:..::|.|::.| |.:|...|.||..::.
Yeast   268 VLFSATFADAVRQYAKKIVPNANTLELQTNE---VNVDAIKQLYMDCKNEADKFDVLTELYGLMT 329

  Fly   284 FNQVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEERLNRYQQFKDFQKRILVATNLFGRGM 348
            ....:|||.:.:....|...|..:......:|..:..:||......|::.:.::|:.||:..||:
Yeast   330 IGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLITTNVLARGI 394

  Fly   349 DIERVNIVFNYDMP------EDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNEVQDRF-DV 406
            ||..|::|.|||:|      .|..||:||:.|.||||.||:||:||.|:|...||:.:|..| |:
Yeast   395 DIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFVHDKNSFNILSAIQKYFGDI 459

  Fly   407 NISELPEE 414
            .::.:|.:
Yeast   460 EMTRVPTD 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel25E	NP_723089.1	DEADc_DDX39	40..248	CDD:350708	65/214 (30%)
		SF2_C_DEAD	259..388	CDD:350174	44/135 (33%)
DBP5	NP_014689.1	SrmB	93..482	CDD:440279	119/388 (31%)