Protein Alignment Hel25E and ddx20

DIOPT Version :10

• Sequence 1: NP_723089.1
• Gene: Hel25E / 33781
• FlyBaseID: FBgn0014189
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001116795.2
• Gene: ddx20 / 556273
• ZFINID: ZDB-GENE-030131-202
• Length: 789
• Species: Danio rerio
• Alignment Length: 430
• Identity: 147/430 - (34%)
• Similarity: 224/430 - (52%)
• Gaps: 41/430 - (9%)

  Fly    14 EQTETTAVENQEAPKK------------DVKGTYVSIHSSG--FRDFLLKPEILRAIVDCGFEHP 64
            |:||.....|..|..|            ||      :.|.|  |...||...:|..:...||:.|
Zfish    19 EETERCRDRNMAASVKAAHELQSRTRTDDV------LISGGVEFSSLLLSKPVLEGLSASGFQRP 77

  Fly    65 SEVQHECIPQAVLGMDILCQAKSGMGKTAVFVLATLQQLEPSDNNTCHVLVMCHTRELAFQISKE 129
            |.:|.:.||....|:|::.|||||.|||.||....|..| ..:|.|..|||:..|||:|.||...
Zfish    78 SPIQLKAIPLGRCGLDLIVQAKSGTGKTCVFTTIALDSL-ILENATTQVLVLAPTREIAVQIHAV 141

  Fly   130 YERFSKYMPTVKVAVFFGGMAIQKDEETLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFVLDE 194
            .......|..::..||.||..|.:|::.||.  .||.:|:||||..||....|.:..::.|||||
Zfish   142 VMAIGSAMEGLECHVFIGGRPISQDKQHLKK--CHIAIGSPGRIKQLIEMGALMVSSIRLFVLDE 204

  Fly   195 CDKMLEQLDMRRDVQE----IFRSTPHGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVD--DEAK 253
            .||:||. |.....||    |:.|.|..||::..|||..:.:.....::|::|..|.::  |...
Zfish   205 ADKLLED-DSSSSFQEQINWIYSSLPANKQMLALSATYPESLAQQLSRYMREPTFVRLNPTDPGL 268

  Fly   254 LTLHGLQQHYVNLKEN--------EKNKKLFELLDVLEFNQVVIFVKSVQRCVALSQLLTEQNFP 310
            |   ||:|:|..:..:        ||.:.|.||...:.|||.::|.....|...|:.:|:.:..|
Zfish   269 L---GLKQYYKIVPSHSLPHKVFEEKVQSLLELFSKIPFNQALVFSNLHTRAQHLADILSSKGLP 330

  Fly   311 AIGIHRGMTQEERLNRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARA 375
            |:.|..|::|::||....:.|.:|.|:|::|:|..||:|.|:||:|.|.|:|:|.:||:||:.||
Zfish   331 AVCISGGLSQDQRLEAMWKLKQYQCRVLISTDLTSRGIDAEKVNLVINLDVPQDWETYMHRIGRA 395

  Fly   376 GRFGTKGLAITFVSDENDAKILNEVQDRFDVNISELPEEI 415
            |||||.|:|:|:.....:...:..:..:..:::..||:.|
Zfish   396 GRFGTLGVAVTYCCHGEEENKMMAIAQKCSLDLMHLPDPI 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel25E	NP_723089.1	DEADc_DDX39	40..248	CDD:350708	80/213 (38%)
		SF2_C_DEAD	259..388	CDD:350174	53/136 (39%)
ddx20	NP_001116795.2	None