Protein Alignment Hel25E and Ddx39b

DIOPT Version :10

• Sequence 1: NP_723089.1
• Gene: Hel25E / 33781
• FlyBaseID: FBgn0014189
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_062667.1
• Gene: Ddx39b / 53817
• MGIID: 99240
• Length: 428
• Species: Mus musculus
• Alignment Length: 426
• Identity: 360/426 - (84%)
• Similarity: 390/426 - (91%)
• Gaps: 5/426 - (1%)

  Fly     1 MADND---DLLDYEDEEQTETTAVENQEAP-KKDVKGTYVSIHSSGFRDFLLKPEILRAIVDCGF 61
            ||:||   :||||||:|.......:..||| ||||||:|||||||||||||||||:|||||||||
Mouse     1 MAENDVDNELLDYEDDEVETAAGADGTEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGF 65

  Fly    62 EHPSEVQHECIPQAVLGMDILCQAKSGMGKTAVFVLATLQQLEPSDNNTCHVLVMCHTRELAFQI 126
            ||||||||||||||:||||:||||||||||||||||||||||||..... .||||||||||||||
Mouse    66 EHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQV-SVLVMCHTRELAFQI 129

  Fly   127 SKEYERFSKYMPTVKVAVFFGGMAIQKDEETLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFV 191
            ||||||||||||.|||||||||::|:||||.||...||||||||||||||.|||.||||.:|||:
Mouse   130 SKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFI 194

  Fly   192 LDECDKMLEQLDMRRDVQEIFRSTPHGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTL 256
            ||||||||||||||||||||||.|||.||||||||||||:|||||:||||||||::||||.||||
Mouse   195 LDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTL 259

  Fly   257 HGLQQHYVNLKENEKNKKLFELLDVLEFNQVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQE 321
            |||||:||.||:||||:|||:||||||||||||||||||||:||:|||.|||||||.|||||.||
Mouse   260 HGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQE 324

  Fly   322 ERLNRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAIT 386
            |||:|||||||||:||||||||||||||||||||.||||||||||||||||||||||||||||||
Mouse   325 ERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAIT 389

  Fly   387 FVSDENDAKILNEVQDRFDVNISELPEEIDLSTYIE 422
            ||||||||||||:|||||:|||||||:|||:|:|||
Mouse   390 FVSDENDAKILNDVQDRFEVNISELPDEIDISSYIE 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel25E	NP_723089.1	DEADc_DDX39	40..248	CDD:350708	179/207 (86%)
		SF2_C_DEAD	259..388	CDD:350174	115/128 (90%)
Ddx39b	NP_062667.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		13/29 (45%)
		DEADc_DDX39	44..251	CDD:350708	179/207 (86%)
		Q motif	45..73		26/27 (96%)
		DECD box	196..199		2/2 (100%)
		SF2_C_DEAD	262..391	CDD:350174	115/128 (90%)