DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hel25E and Gem3

DIOPT Version :10

Sequence 1:NP_723089.1 Gene:Hel25E / 33781 FlyBaseID:FBgn0014189 Length:424 Species:Drosophila melanogaster
Sequence 2:NP_524019.1 Gene:Gem3 / 39195 FlyBaseID:FBgn0011802 Length:1028 Species:Drosophila melanogaster


Alignment Length:382 Identity:120/382 - (31%)
Similarity:203/382 - (53%) Gaps:14/382 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 FRDFLLKPEILRAIVDCGFEHPSEVQHECIPQAVLGMDILCQAKSGMGKTAVFVLATLQQLEPSD 107
            |.:..|...:|..:....|..|:::|...||.|:..||::.|:|||.|||.::|:|.:|...|:.
  Fly    27 FEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIAVVQSFNPNI 91

  Fly   108 NNTCHVLVMCHTRELAFQISKEYERFSKYMPTVKVAVFFGGMAIQKDEETLKSGTPHIVVGTPGR 172
            |.. |.:::..|||||.|:...:....|.....|.:.|.||..:.||.:.:...  .:::|||||
  Fly    92 NQP-HAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNES--RVIIGTPGR 153

  Fly   173 ILALIRNKKLNLKLLKHFVLDECDKMLEQLDMRRDVQEIFRSTPHGKQVMMFSATLSKDIRPVCK 237
            :|.|..|:..::..|:..||||.|::.:...::..|.::..:.|..:|::..|||..:::.....
  Fly   154 LLHLYENRVFDVSKLRLLVLDEADQLYQTKSLQHTVSKLIEAMPKNRQIIACSATYDQNLDERLA 218

  Fly   238 KFMQDPMEVYVDDEAKLTLHGLQQHYVNLKENE--------KNKKLFELLDVLEFNQVVIFVKSV 294
            |.|..||.:...:.|.:.| |::|....|.:..        |.:.|.::.:.|.:.|.:||..|.
  Fly   219 KVMDKPMLISNSERATVLL-GIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAIIFASSQ 282

  Fly   295 QRCVALSQLLTEQNFPAIGIHRGMTQEERLNRYQQFKDFQKRILVATNLFGRGMDIERVNIVFNY 359
            .|..:....||........|...|.|.|||:.::.:::|..||||||:|..||:|....|:|.|.
  Fly   283 MRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVINI 347

  Fly   360 DMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNEVQDRFDV--NISELPEE 414
            |.|:|..|||||:.||||||:||:||||::.:.:::...|:..:...  ::.|.|:|
  Fly   348 DPPQDHVTYLHRIGRAGRFGSKGIAITFIASKKESQRFREMSKKIATAWSVLEFPKE 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hel25ENP_723089.1 DEADc_DDX39 40..248 CDD:350708 61/204 (30%)
SF2_C_DEAD 259..388 CDD:350174 51/136 (38%)
Gem3NP_524019.1 SrmB 26..409 CDD:440279 120/382 (31%)

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