Protein Alignment Hel25E and CG10077

DIOPT Version :10

• Sequence 1: NP_723089.1
• Gene: Hel25E / 33781
• FlyBaseID: FBgn0014189
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_648062.2
• Gene: CG10077 / 38756
• FlyBaseID: FBgn0035720
• Length: 818
• Species: Drosophila melanogaster
• Alignment Length: 414
• Identity: 125/414 - (30%)
• Similarity: 213/414 - (51%)
• Gaps: 20/414 - (4%)

  Fly    15 QTETTAVENQEAPKKD-VKGTYVSIHSSGFRDFLLKPEILRAIVDCGFEHPSEVQHECIPQAVLG 78
            :|||....|:...|.| |....:.....||.|:::. ||.:.    ||..|:.:|.:..|.|:.|
  Fly   135 ETETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMN-EIRKQ----GFAKPTAIQAQGWPIAMSG 194

  Fly    79 MDILCQAKSGMGKTAVFVLATL------QQLEPSDNNTCHVLVMCHTRELAFQISKEYERFSKYM 137
            .|::..|::|.|||..:||..:      .:||..|...  .||:..|||||.||.:....|.. .
  Fly   195 RDLVGVAQTGSGKTLAYVLPAVVHINNQPRLERGDGPI--ALVLAPTRELAQQIQQVAIEFGS-N 256

  Fly   138 PTVKVAVFFGGMAIQKDEETLKSGTPHIVVGTPGRILALIRNKKLNLKLLKHFVLDECDKMLEQL 202
            ..|:....|||....:....|:.|. .||:.||||::..:.....:||...:.||||.|:||: :
  Fly   257 THVRNTCIFGGAPKGQQARDLERGV-EIVIATPGRLIDFLERGTTSLKRCTYLVLDEADRMLD-M 319

  Fly   203 DMRRDVQEIFRSTPHGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTLHGLQQHYVNLK 267
            .....:::|.:.....:||:|:|||..|::|.:.::|:.:.::|.:...:....|.:.|......
  Fly   320 GFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQIVDVCD 384

  Fly   268 ENEKNKKLFELL-DVLEFNQ--VVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEERLNRYQQ 329
            ||||..||.:|| |:...|:  .:|||::.:|...:::.::.|.:.|..||...:|:||......
  Fly   385 ENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSS 449

  Fly   330 FKDFQKRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDA 394
            |::.:..|||||::..||:|::.|..|.|||.|.:|:.|:||:.|.||....|.|.|..:..|..
  Fly   450 FRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHSNAN 514

  Fly   395 KILNEVQDRFDVNISELPEEIDLS 418
            |..:.:|...:.|.:..|:.::::
  Fly   515 KANDLIQVLREANQTINPKLMNMA 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel25E	NP_723089.1	DEADc_DDX39	40..248	CDD:350708	65/213 (31%)
		SF2_C_DEAD	259..388	CDD:350174	47/131 (36%)
CG10077	NP_648062.2	DEAD-like_helicase_N	49..544	CDD:475120	125/414 (30%)