Protein Alignment Hel25E and CG10333

DIOPT Version :10

• Sequence 1: NP_723089.1
• Gene: Hel25E / 33781
• FlyBaseID: FBgn0014189
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_609888.2
• Gene: CG10333 / 35112
• FlyBaseID: FBgn0032690
• Length: 822
• Species: Drosophila melanogaster
• Alignment Length: 465
• Identity: 135/465 - (29%)
• Similarity: 224/465 - (48%)
• Gaps: 63/465 - (13%)

  Fly     1 MADNDDLLDYEDEEQTETTAVENQEAPKKD-----------VKGTYV-----SIHSSGFRDFLLK 49
            |...:|...::|...:|.   ||.|..::|           :||..:     |.:.|||     .
  Fly   346 MKRKEDKQKWDDRHWSEK---ENDEMTERDWRIFREDYNVTIKGGRIPNPIRSWNESGF-----P 402

  Fly    50 PEILRAIVDCGFEHPSEVQHECIPQAVLGMDILCQAKSGMGKTAVFV---------LATLQQLEP 105
            .||:..|...|::.|:.:|.:.||..:...||:..|::|.|||..|:         |..:::||.
  Fly   403 KEIIDIIDKVGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLED 467

  Fly   106 SDNNTCHVLVMCHTRELAFQISKEYERFSKYMPTVKVAVFFGGMAIQKDEETLKSGTPHIVVGTP 170
            .|... :.::|..|||||.||.:|..:|.:.: .::..|..||::.::....|:.|. .||:.||
  Fly   468 VDQGP-YAIIMAPTRELAQQIEEETTKFGQPL-GIRTVVVVGGLSREEQGFRLRLGC-EIVIATP 529

  Fly   171 GRILALIRNKKLNLKLLKHFVLDECDKMLEQLDMRRDVQEIFRSTP------------------- 216
            ||::.::.|:.|.|....:.||||.|:|:: :....|||:|....|
  Fly   530 GRLIDVLENRYLVLNQCTYIVLDEADRMID-MGFEPDVQKILEYMPVTNLKPDTEEAEDETKLME 593

  Fly   217 ------HGKQVMMFSATLSKDIRPVCKKFMQDPMEVYVDDEAKLTLHGLQQHYVNLKENEKNKKL 275
                  ..:|.:||:||:...:..:.:.:::.|..||:....|.|....|..|: :.||:|.|||
  Fly   594 NFYTKKKYRQTVMFTATMPPAVERLARTYLRRPATVYIGSVGKPTERTEQIVYM-MGENDKRKKL 657

  Fly   276 FELLDVLEFNQVVIFVKSVQRCVALSQLLTEQNFPAIGIHRGMTQEERLNRYQQFKDFQKRILVA 340
            .|:|.......|:|||...:....|::.|.:..:.:..:|.|..||:|.......|...|.||||
  Fly   658 MEILSRKIDPPVIIFVNQKKGADVLAKGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVA 722

  Fly   341 TNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNEVQDRFD 405
            |::.|||:||:.|::|.||||.:..:.|.||:.|.||.|..|.||:||:.::.|...:..|....
  Fly   723 TDVAGRGIDIKDVSLVINYDMAKTIEDYTHRIGRTGRAGKTGCAISFVTKDDSALFYDLKQCVSA 787

  Fly   406 VNISELPEEI 415
            ..:|..|.|:
  Fly   788 SPVSTCPPEL 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hel25E	NP_723089.1	DEADc_DDX39	40..248	CDD:350708	65/241 (27%)
		SF2_C_DEAD	259..388	CDD:350174	49/128 (38%)
CG10333	NP_609888.2	DUF5401	<66..354	CDD:375164	2/7 (29%)
		SrmB	395..783	CDD:440279	121/397 (30%)